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WorksheetsDissolution quiz -Practice school
Total questions: 11
Worksheet time: 4mins
Which among the following is the type - 3 dissolution setup, as recommended by US-FDA
Basket type
Reciprocating cylinder
Paddle type
Flow through cell
Drug dissolution is a _____ process involving heterogeneous reactions at the solid–liquid interphase.
None of above
linear steps
single step
Multi-step
Which parameter is primarily measured in a dissolution test?
Integrity of tablet
amount of drug released over time
Drug content/purity
Release of colour from tablet
Which wavelength is typically used to analyze paracetamol during UV spectrophotometric dissolution assay?
234
243
257
220
During the analysis of content from dissolution of paracetamol tablets, if absorbance keeps increasing beyond the calibration range, what should be done?
Continue measurement
Increase wavelength
Dilute the sample appropriately
Change the buffer
Which parameter remains constant in a dissolution test unless intentionally varied?
Time of sampling
Type of medium
Speed of paddle
Surface area of drug
The calibration curve in dissolution helps to:
Set zero in the spectrophotometer
Compare unknown absorbance to known concentrations
Measure the intensity of peaking of drug sample
Validate the drug profile
Why is degassing of dissolution medium done?
To sterilize it
To improve drug solubility
To avoid bubble formation on dosage form
To reduce pH
The term “Q value” in dissolution refers to:
Quantity of drug in tablet
Quality of UV spectrum absorbance predicted
Specified amount (%) of drug release required
Rate of drug absorption
what is the maximum volume of the dissolution media holding bowl in the apparatus (in ml)
1000
1100
500
900
How was the practical session, for the past two days?
Good, wanted more like this
Ok Ok session..
When will you leave us for break/lunch
