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BiTE and CAR T-cell therapy

Total questions: 10

Worksheet time: 4mins

Name
Class
Date
1.

Which type of immunotherapy uses genetically modified immune cells to target specific cancer cells?

a)

Cytokine therapy

b)

Cancer vaccines

c)

Checkpoint inhibitors

d)

CAR T-cell therapy

2.

What is the primary purpose of lymphodepletion prior to CAR-T cell treatment?

a)

To remove T-cells

b)

To kill or slow the growth of cancer cells

c)

To prevent ICANS

d)

To prevent cancer recurrence

3.

Which of the following is a common side effect of CAR T-cell therapy?

a)

Bleeding

b)

Hair loss

c)

Muscle pain

d)

Hepatotoxicty

4.

You're creating a new BiTE therapy. What cancer would be easiest to target?

a)

Breast cancer

b)

Prostate cancer

c)

Multiple myeloma

d)

Melanoma

5.

What is the first medication you would consider giving to a patient with grade 3 CRS?

a)

Aspirin

b)

Methylprednisolone

c)

Dexrazoxane

d)

Prednisone

6.

In what scenario might a doctor choose to use immunotherapy over chemotherapy?

a)

When the cancer is localized and small

b)

When the patient has a strong immune system

c)

When the patient has failed chemotherapy

d)

When the patient prefers not to have any treatment

7.

What is a major limitation for CAR T-cell therapy?

a)

Side effects

b)

Manufacturing time

c)

Training staff

d)

Increased fatigue

8.

How can the effectiveness of immunotherapy be measured in a patient?

a)

By assessing changes in tumor size through imaging

b)

By monitoring hair growth

c)

By evaluating blood pressure

d)

By measuring appetite changes

9.

Which type of cancer is most commonly treated with CAR-T cell therapy?

a)

Skin cancer

b)

Acute lymphoblastic leukemia

c)

Prostate cancer

d)

Breast cancer

10.

Which type of immunotherapy uses antibodies that recognize 2 antigens to help T-cells kill cancer

a)

Checkpoint Inhibitors

b)

CAR T-cell

c)

Vaccines

d)

BiTE therapy