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[LRH] CC Primer Part 2

Total questions: 75

Worksheet time: 43mins

Name
Class
Date
1.

main storage of lipids

a)

triglycerides

b)

cholesterol

c)

phospholipid

2.

precursor of steroid horomone

a)

triglycerides

b)

cholesterol

c)

phospholipid

3.

most abundant lipid in the body

a)

triglycerides

b)

cholesterol

c)

phospholipid

4.

main transporter of exogenous triglycerides

a)

chylomicron

b)

very low density lipoprotein

c)

low density lipoprotein

d)

high density lipoprotein

5.

largest but the least dense

a)

chylomicron

b)

very low density lipoprotein

c)

low density lipoprotein

d)

high density lipoprotein

6.

main transporter of endogenous triglycerides

a)

chylomicron

b)

very low density lipoprotein

c)

low density lipoprotein

d)

high density lipoprotein

7.

main transporter of cholesterol to the peripheral tissue

a)

chylomicron

b)

very low density lipoprotein

c)

low density lipoprotein

d)

high density lipoprotein

8.

bad cholesterol

a)

chylomicron

b)

very low density lipoprotein

c)

low density lipoprotein

d)

high density lipoprotein

9.

reverse cholesterol pathway

a)

chylomicron

b)

very low density lipoprotein

c)

low density lipoprotein

d)

high density lipoprotein

10.

smallest but the most dense

a)

chylomicron

b)

very low density lipoprotein

c)

low density lipoprotein

d)

high density lipoprotein

11.

carries endogenous TAG and cholesterol

a)

intermediate density lipoprotein

b)

lipoprotein A

c)

LIPOPROTEIN X

d)

B-VLDL

12.

Sinking prebeta lipoprotein

a)

intermediate density lipoprotein

b)

lipoprotein A

c)

LIPOPROTEIN X

d)

B-VLDL

13.

it interferes with the clot lysis because it competes with plasmin

a)

intermediate density lipoprotein

b)

lipoprotein A

c)

LIPOPROTEIN X

d)

B-VLDL

14.

obstructive jaundice

a)

intermediate density lipoprotein

b)

lipoprotein A

c)

LIPOPROTEIN X

d)

B-VLDL

15.

floating beta lipoprotein; found in type 3 hyperlipoproteinemia

a)

intermediate density lipoprotein

b)

lipoprotein A

c)

LIPOPROTEIN X

d)

B-VLDL

16.

APO A

a)

HDL

b)

Chylomicrons

c)

LDL, VLDL

d)

Chylomicrons and VLDL

17.

Choose the incorrect match

a)

APO B48: Chylomicrons

b)

APO B100: LDL AND VLDL

c)

APO C1 AND APO C2: HDL

d)

APO E: IDL, CHYLOMICRONS

18.

Characterized by markedly reduced or almost efficient HDL

a)

Tangier

b)

Bassen Kronzweig

c)

andersons disease

d)

sitosterolemia

19.

defective apo-B synthesis

a)

Tangier

b)

Bassen Kronzweig

c)

andersons disease

d)

sitosterolemia

20.

defective apo-B48 synthesis

a)

Tangier

b)

Bassen Kronzweig

c)

andersons disease

d)

sitosterolemia

21.

Familial LPL Deficiency

a)

type I

b)

Type IIA

c)

Type IIB

d)

Type

22.

choose the correct match

a)

Type IIA: Familial hypercholesterolemia

b)

Type IIB: Familial Combined hyperlipidemia

c)

Type III: Familial dysbetalipoproteinemia

d)

Type IV: Familial hypertriglyceridemia

e)

Type V: Familial hyperlipoproteinemia

23.

Familial hyperlipoproteinemia

a)

Increase CM, Increase TAG

b)

Increase TAG and CHOL, Increase CM and VLDL

c)

Increase CHOL, Increase LDL

d)

Increase TAG, Increase VLDL

24.

Familial hypercholesterolemia

a)

Increase CM, Increase TAG

b)

Increase TAG and CHOL, Increase CM and VLDL

c)

Increase CHOL, and LDL

d)

Increase TAG, Increase VLDL

25.

Familial LPL Deficiency

a)

Increase CM, Increase TAG

b)

Increase TAG and CHOL, Increase CM and VLDL

c)

Increase CHOL, and LDL

d)

Increase TAG, Increase VLDL

26.

Familial Combined hyperlipidemia

a)

Increase CM, Increase TAG

b)

Increase TAG and CHOL, Increase CM and LDL

c)

Increase CHOL, and LDL

d)

Increase TAG, Increase VLDL

27.

Lipid profile includes

a)

HDL

b)

VLDL

c)

LDL

d)

CHOLESTEROL

e)

TAG

28.

Reference method for lipoproteins

(a)  

29.

the most anodal

a)

chylomicrons

b)

ldl

c)

vldl

d)

hdl

30.

high cholesterol

a)

> 200 mg/dl

b)

> 200 mmol/l

c)

>240 mg/dl

d)

>240 mmol/l

31.

high TAG

a)

> 500 mg/dl

b)

> 500 mmol/l

c)

>240 mg/dl

d)

>240 mmol/l

32.

high LDL

a)

> 500 mg/dl

b)

> 500 mmol/l

c)

>190 mg/dl

d)

>190 mmol/l

33.

HIGH RISK FOR CHD

a)

40 MG/DL

b)

28 MG/DL

c)

140 MG/DL

d)

120 MG/DL

34.

alpha 1 globulin

a)

a1 antitrypsin, a1 fetoprotein, GC globulin, a1 antichymotrypsin

b)

haptoglobin, alpha 2 macroglobulin, ceruloplasmiin

c)

transferrin, hemopexin, b2-microglobulin

d)

immunoglobulins

35.

alpha 2 globulin

a)

a1 antitrypsin, a1 fetoprotein, GC globulin, a1 antichymotrypsin

b)

haptoglobin, alpha 2 macroglobulin, ceruloplasmiin

c)

transferrin, hemopexin, b2-microglobulin

d)

immunoglobulins

36.

beta globulin

a)

a1 antitrypsin, a1 fetoprotein, GC globulin, a1 antichymotrypsin

b)

haptoglobin, alpha 2 macroglobulin, ceruloplasmiin

c)

transferrin, hemopexin, b2-microglobulin

d)

immunoglobulins

37.

choose the false statement

a)

albumin: detect malnutrition and transports thyroxine

b)

albumin: most abundant plasma protein

c)

alpha 1 antitrypsin: major inhibitor of protease activity

d)

alpha 1 fetoprotein: greatest affinity for progesterone

38.

choose the false statement

a)

albumin: detect malnutrition and transports thyroxine

b)

albumin: most abundant plasma protein

c)

alpha 1 antitrypsin: vitamin d carrier

d)

alpha 1 fetoprotein: tumor marker for liver cancer

39.

choose the false statement

a)

haptoglobin: binds free hemoglobin

b)

alpha 2 microglobulin: increased in nephrosis

c)

ceruloplasmin: transports iron

d)

hemopexin: bind to heme and helps diagnose early hemolysis

40.

choose the false statement

a)

haptoglobin: binds free hemoglobin

b)

b2 microglobulin: increased in nephrosis

c)

transferrin: transports iron

d)

decrease ceruloplasmin: wilson's disease and menkes kinky hair syndrome

41.

cirrhosis

a)

beta gamma bridging

b)

spiked increase of gamma

c)

low albumin, high alpha 2 and increase beta

d)

low or flat curve in gamma region

42.

polyclonal gammopathy

a)

beta gamma bridging

b)

spiked increase of gamma

c)

low albumin, high alpha 2 and increase beta

d)

low or flat curve in gamma region

43.

nephrotic syndrome

a)

beta gamma bridging

b)

spiked increase of gamma

c)

low albumin, high alpha 2 and increase beta

d)

low or flat curve in gamma region

44.

inflammation

a)

beta gamma bridging

b)

spiked increase of gamma

c)

low albumin, high alpha 2 and increase beta

d)

alpha 1, alpha 2 and beta increase

45.

earliest cardiac marker

(a)  

46.

first enzyme to increase during heart attack

(a)  

47.

gold standard for the diagnosis of acute coronary syndrom

(a)  

48.

glycoprotein used to help predict short term risk for premature delivery

a)

fetal fibronectin

b)

plasma fibronectin

c)

alpha fetoprotein

49.

early assessment of changes to GFR

(a)  

50.

help differentiate alzheimers from other forms of dementia.

(a)  

51.

reference method for protein measurement

a)

biuret method

b)

kjeldahl

c)

bromcresol green albumin

52.

not polar

a)

Unconjugated bilirubin

b)

conjugated bilirubin

53.

attached to a protein

a)

Unconjugated bilirubin

b)

conjugated bilirubin

c)

delta bilirubin

54.

RBC Destruction yields what product

a)

heme

b)

water

c)

iron

d)

protein

55.

select the correct order

a)

Heme - B2 - Liver - B1 - Intestines - Urobilinogen - Feces and Urine

b)

Globin - B1 - Liver - B2 - Intestines - Urobilinogen - Feces and Urine

c)

Heme - B1 - Liver - B2 - Intestines - Urobilinogen - Feces and Urine

d)

Heme - B1 - Kidney - B2 - Intestines - Urobilinogen - Feces and Urine

56.

serum bilirubin: increased

urine bilirubin: negative

a)

pre hepatic

b)

hepatic

c)

post hepatic

57.

it is a bilirubin transport disorder

a)

gilbert's syndrome

b)

crigler-najjar syndrome

c)

DUBIN JOHNSON SYNDROME

d)

LUCEY-DRISCOLL SYNDROME

e)

ROTOR SYNDROME

58.

disorder where B1 cannot be conjugated to B2 in the liver cell

a)

gilbert's syndrome

b)

crigler-najjar syndrome

c)

DUBIN JOHNSON SYNDROME

d)

LUCEY-DRISCOLL SYNDROME

e)

ROTOR SYNDROME

59.

it is a bilirubin transport disorder

a)

gilbert's syndrome

b)

crigler-najjar syndrome

c)

DUBIN JOHNSON SYNDROME

d)

LUCEY-DRISCOLL SYNDROME

e)

ROTOR SYNDROME

60.

B2 cannot enter the intestine due to no UDPGT

a)

gilbert's syndrome

b)

crigler-najjar syndrome

c)

dubin johnson syndrome

d)

lucey driscoll syndrome

e)

ROTOR SYNDROME

61.

both b2 and b1 is elevated

a)

gilbert's syndrome

b)

crigler-najjar syndrome

c)

dubin johnson syndrome

d)

lucey driscoll syndrome

e)

ROTOR SYNDROME

62.

there is a circulating inhibitor of bilirubin conjugation in the blood

a)

gilbert's syndrome

b)

crigler-najjar syndrome

c)

dubin johnson syndrome

d)

lucey driscoll syndrome

e)

rotor syndrome

63.

more than 80% damage in the liver

a)

hepatitis

b)

cirrhosis

64.

select the false statement

a)

evelyn malloy uses alkaline pH

b)

The dissociating agent of Jendrassik-Grof is Caffeine sodium benzoate which is also preferred

c)

the diazo product of evelyn mallo is red or reddish purple and read at 560 nm

d)

the diazo product of Jendrassik-Grof is blue which is read at 600nm

65.

select the false statement

a)

inulin clearance is most commonly used

b)

creatinine clearance is directly related to muscle mass

c)

earliest GFR test is the urea clearance test

d)

cystatin C denotes damage of the proximal convoluted tubule

66.

major end product of protein catabolism

(a)  

67.

major end product of muscle metabolism

(a)  

68.

marked elevation of plasma urea and other NPNs accompanied by acidemia and hyperkalemia and associated with renal failure with presence of burr cells

a)

uremia

b)

pre renal azotemia

c)

renal azotemia

d)

post renal azotemia

69.

result of reduced renal blood flow includes shock, hemorrgae, heart failure and dehydratyion

a)

uremia

b)

pre renal azotemia

c)

renal azotemia

d)

post renal azotemia

70.

very high plasma urea concentration accompanied by renal failure

a)

uremia

b)

pre renal azotemia

c)

renal azotemia

d)

post renal azotemia

71.

obstruction anywhere in the urinary tract like renal calculi and tumors of the bladder

a)

uremia

b)

pre renal azotemia

c)

renal azotemia

d)

post renal azotemia

72.

major end product of purine metabolism

(a)  

73.

select false statement

a)

highest protein in nephrotic syndrome

b)

red cells and red cell casts in urine for glomerulonephritis

c)

cholesterol crystals and wacy casts are found in the urine of patients suffering from renal failure

d)

abnormal alteration in the excretion of amino acids is seen in tubular defects

74.

product of amino acids deamination

(a)  

75.

most commonly seen in children with viral infection and takes too much aspirin causing too high ammonia levels

a)

hepatitis

b)

cirrhosis

c)

hepatic and renal failure

d)

reye syndrome