NEW
Font size
WorksheetsKROK 1 Pharmacology Test
Total questions: 23
Worksheet time: 12mins
Which of the following adverse effects is a common reason for discontinuing Metformin therapy in patients with Type 2 Diabetes Mellitus?
Thyroid dysfunction.
Severe hypoglycemia.
Gastrointestinal disturbances (diarrhea, nausea).
Peripheral edema and weight gain.
Persistent dry cough.
A patient on Warfarin therapy develops a significantly elevated International Normalized Ratio (INR) and presents with bleeding. Which agent is the most appropriate initial antidote to rapidly reverse the anticoagulant effect?
Fresh Frozen Plasma (FFP) or Prothrombin Complex Concentrate (PCC).
Protamine sulfate.
Aspirin.
Desmopressin.
Vitamin K (Phytonadione).
A patient who began taking the selective serotonin reuptake inhibitor (SSRI) Fluoxetine is also prescribed a Monoamine Oxidase Inhibitor (MAOI) for a different condition. This combination is absolutely contraindicated due to the high risk of which life-threatening syndrome?
Neuroleptic Malignant Syndrome (NMS).
Hepatic encephalopathy.
Serotonin Syndrome.
Hypertensive crisis.
Agranulocytosis.
Which antipsychotic drug carries a significant risk of agranulocytosis and requires mandatory weekly to biweekly Complete Blood Count (CBC) monitoring?
Quetiapine.
Risperidone.
Olanzapine.
Clozapine.
Haloperidol.
A patient with urolithiasis has unbearable spasmodic pain. To prevent pain shock,
he has been given an injection of atropine along with a narcotic analgesic having
antispasmodic effect. What drug was it?
Morphine hydrochloride
Tramadol
Nalorphine
Ethylmorphine hydrochloride
Promedol
Despite the administration of cardiotonics and a thiazide diuretic a patient with
chronic heart failure has persistent edemata, there is a risk of ascites. What
medication should be administered in order to enhance the diuretic effect of the drugs
used?
Clopamide
Furosemide
Amiloride
Spironolactone
Manithol
A 60-year-old male patient has a 9-year history of diabetes and takes insulin Semi-
lente for the correction of hyperglycemia. 10 days ago he began taking anaprilin for
hypertension. One hour after administration of the antihypertensive drug the patient
developed hypoglycemic coma. What is the mechanism of hypoglycemia in case of
anaprilin use?
Reduction of glucagon half-life
Inhibition of glycogenolysis
Increase of insulin Semilente half-life
Increase of bioavailability of insulin Semilente
Decrease in glucose absorption
A patient has been administered an anti-inflammatory drug that blocks the action
of cyclooxygenase. Specify this anti-inflammatory agent:
Creatine
Analgene
Allopurinol
Thiamin
Aspirin
A pneumonia patient has been administered acetylcysteine as a part of complex
therapy. What principle of therapy was taken into consideration when applying this
drug?
Etiotropic
Symptomatic
Pathogenetic
Antimicrobial
Immunomodulatory
A 26-year-old female patient with bronchitis has been administered a broad
spectrum antibiotic as a causal treatment drug. Specify this drug:
Ambroxol
Interferon
BCG vaccine
Doxycycline
Dexamethasone
A 12-year-old child has a viral infection complicated by obstructive bronchitis.
Bronchospasm can be eliminated by inhalations of a drug from the following
pharmacological group:
M-anticholinergics
B2-agonists
N-cholinomimetics
B2-adrenergic blockers
Analeptics
A patient has recurrent attacks of epileptic seizures and stays unconscious between
them. In order to stop convulsions the drugs of the following group should be used in
the first place:
Tranquilizers
Neuroleptics
Muscle relaxants
Sedatives
Analeptics
A patient with arthritis and varicose veins has been taking a non-steroidal anti-
inflammatory drug for a long time, which caused thrombosis of skin veins. Which of
the following drugs might have caused this complication?
Phenylbutazone
Indomethacin
Aspirin
Celecoxib
Ibuprofen
A patient with bacterial periodontitis has been administered iontophoresis with
the use ofiodine solution. Specify the mechanism of therapeutic action of this agent:
Inhibition of the cell wall formation
Reduction of the nitro group under the effect of nitroreductase
Albumin formation
Changing the surface tension of the bacterial cell membrane
Substitution of hydrogen atoms when the protein amino group contains a nitrogen
atom
A patient has arterial hypertension. What long-acting drug from the group of
calcium channelblockers should be prescribed?
Octadine
Amlodipine
Pyrroxanum
Atenolol
Reserpine
As a result of a home injury, a patient suffered a significant blood loss, which led
to a fall inblood pressure. Rapid blood pressure recovery after the blood loss is
provided by the following hormones:
Adrenaline, vasopressin
Cortisol
Sex hormones
Oxytocin
Aldosterone
A 65-year-old female patient has chronic constipations due to the colon
hypotonia. What drug should be chosen in this case?
Castor oil
Bisacodyl
Magnesium sulfate
Neostigmine methylsulfate
Metoclopramide
Administration of doxycycline hydrochloride caused an imbalance of the
symbiotic intestinalmicroflora. Specify the kind of imbalance caused by the antibiotic
therapy:
Dysbacteriosis
Sensibilization
Idiosyncrasy
Superimposed infection
Bacteriosis
An unconscious patient was delivered to the admission ward. Objectively: the
patient’s skin is cold, pupils are myotic, he has laboured Cheyne-Stokes respiration,
arterial pressure is low, urinary bladder is full. What substance has caused
intoxication?
Tranquilizers
Non-narcotican algetics
Muscarinic receptor blockers
Adrenaline
Narcotic analgetics
A woman works as railway traffic controller. She suffers from seasonal
vasomotor rhinitis and gets treatment in the outpatient setting. She was prescribed an
antihistamine that has no effect upon central nervous system. What drug is it?
Promethazine
Dimedrol
Loratadine
Suprastin
Tavegil
A patient who suffers from insomnia caused by emotional disorder was
prescribed a hypnotic drug with tranquillizing effect. What hypnotic was prescribed?
Nitrazepam
Phenobarbital
Chloralhydrate
Sodiumethaminal
Bromisoval
A 4 year old child was admitted to the orthopaedic department with shin fracture
together with displacement. Bone fragments reposition requires preliminary
analgesia. What medication should be chosen?
Analgin
Promedol
Morphinehydrochloride
Panadol
-
A 65 year old female patient suffers from chronic renal insufficiency
accompanied by evident edemata caused by chronic glomerulonephritis. What
diuretic should be administered for forced diuresis?
Hydrochlorothiazide
Chlorthalidone
Cyclometazide
Acetazolamide
Furosemide
