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Peripheral Nerve and Degenerative Neurologic Disorders

Total questions: 58

Worksheet time: 29mins

Name
Class
Date
1.

Which drug is used to treat Parkinson's disease and decreases the presence of tremor, rigidity, and bradykinesia, and improves motor function?

a)

Baclofen

b)

Levodopa/carbidopa

c)

Interferon beta-1b

d)

IVIG (Intravenous Immunoglobulin)

2.

Baclofen is used to treat _________

a)

multiple sclerosis

b)

hypertension

c)

diabetes mellitus

d)

asthma

3.

Which of the following drugs is used to treat Guillain Barre Syndrome?

a)

IVIG (Intravenous Immunoglobulin)

b)

Baclofen

c)

Corticosteroids

d)

Cogentin (Benztropine)

4.

Interferon beta-1b and corticosteroids are used to treat which disease?

a)

Parkinson's Disease

b)

Multiple Sclerosis

c)

Guillain Barre Syndrome

d)

Alzheimer's Disease

5.

Cogentin (Benztropine) is used as adjunctive therapy for which disease?

a)

Multiple Sclerosis

b)

Guillain Barre Syndrome

c)

Parkinson's Disease

d)

Alzheimer's Disease

6.

Parkinson's disease is named after ________, who first described the syndrome in 1871.

a)

James Parkinson

b)

Jean-Martin Charcot

c)

Alois Alzheimer

d)

Sigmund Freud

7.

What is the main cause of Parkinson's disease?

a)

Excess of dopamine

b)

Depletion of dopamine and excess of acetylcholine

c)

Excess of acetylcholine

d)

Depletion of serotonin

8.

Which of the following is NOT a symptom of Parkinson's disease?

a)

Rigidity

b)

Tremors

c)

Increased salivation

d)

High blood pressure

9.

The TRIAD sign in Parkinson's disease includes tremors, bradykinesia, and _________?

a)

rigidity

b)

ataxia

c)

paralysis

d)

spasticity

10.

Which of the following is a late-stage symptom of Parkinson's disease?

a)

Urinary incontinence

b)

Headache

c)

Fever

d)

Rash

11.

Which treatment is NOT commonly seen in Parkinson's disease?

a)

Physical therapy

b)

Emotional support

c)

Complementary and alternative therapies

d)

Surgical treatment

12.

What is the meaning of Sialorrhea?

a)

salivation

b)

headache

c)

fever

d)

nausea

13.

What is the meaning of Rhinorrhea?

a)

runny nose

b)

headache

c)

sore throat

d)

ear pain

14.

What is the meaning of Diarrhea?

a)

runny ass

b)

headache

c)

broken bone

d)

sore throat

15.

Which of the following is a side effect of anticholinergic drugs used in Parkinson's disease therapy?

a)

Dry mouth

b)

Excessive salivation

c)

Increased dopamine

d)

Hallucinations

16.

Which drug increases dopamine levels in the brain for Parkinson's disease?

a)

Benadryl

b)

Mirapex

c)

Atropine

d)

Demerol

17.

Which dietary item should be avoided when taking MAOIs for Parkinson's disease?

a)

Fresh fruit

b)

Aged cheeses

c)

White bread

d)

Milk

18.

Which of the following drugs works by mimicking the actions of dopamine in Parkinson's disease?

a)

Antiviral

b)

Anticholinergic

c)

Levodopa

d)

Demerol

19.

What does Multiple Sclerosis (MS) do? Fill in the blank: MS is a ________ inflammatory disease.

a)

chronic

b)

temporary

c)

bacterial

d)

acute

20.

What does Multiple Sclerosis (MS) do? Fill in the blank: MS causes ________ in the central nervous system (CNS).

a)

demyelination

b)

calcification

c)

hyperplasia

d)

ossification

21.

Which of the following is NOT a symptom of Multiple Sclerosis (MS)?

a)

Motor dysfunction

b)

Mental changes

c)

Problems of coordination

d)

High blood pressure

e)

Sensory dysfunction

22.

The most common type of MS is characterized by periods of ________ and ________.

a)

remission and exacerbation

b)

weakness and paralysis

c)

fatigue and insomnia

d)

pain and numbness

23.

What is the biggest symptom patients suffer from early on in MS?

a)

Muscle spasms

b)

Fatigue

c)

Blurry vision

d)

Lhermitte’s sign

24.

Which of the following is a biologic response modifier drug used in the treatment of MS?

a)

IV methylprednisolone

b)

Adrenocorticotropic hormone (ACTH)

c)

Immunomodulators

d)

Plasmapheresis

25.

Fill in the blank: The drug of choice when the patient is in an acute episode of MS called an MS flare is ________.

a)

IV methylprednisolone

b)

IV acetaminophen

c)

IV amoxicillin

d)

IV diazepam

26.

Which process filters the blood and removes the harmful antibodies in MS treatment?

a)

Plasmapheresis

b)

Autologous stem cell transplantation

c)

IV methylprednisolone

d)

Adrenocorticotropic hormone (ACTH)

27.

Fill in the blank: Adrenocorticotropic hormone (ACTH) is a ________.

a)

steroid

b)

peptide hormone

c)

enzyme

d)

neurotransmitter

28.

What is the most common clinical progression type of Multiple Sclerosis?

a)

Progressive

b)

Relapsing-remitting

c)

Acute

d)

Chronic

29.

What are the main symptoms of Alzheimer's Disease, also known as Senile Dementia?

a)

Memory loss and confusion

b)

Frequent nosebleeds

c)

Sudden weight gain

d)

Improved vision

30.

Which of the following is NOT a symptom of Alzheimer's Disease?

a)

Pathologic changes in the brain tissue

b)

Unknown cause

c)

Atrophy of the muscles

d)

Slow onset, progresses at varying rates of speed

31.

Alzheimer's Disease can occur during ______ or during the later decades of life.

a)

middle age

b)

childhood

c)

adolescence

d)

early infancy

32.

Considerable research is in progress to better define which disease?

a)

Alzheimer's Disease

b)

Diabetes Mellitus

c)

Hypertension

d)

Asthma

33.

Amyotrophic Lateral Sclerosis (ALS) is characterized by degeneration of gray matter in the ______ of the spinal cord and the lower cranial nerves.

a)

anterior horns

b)

posterior columns

c)

lateral funiculi

d)

dorsal roots

34.

Which two muscles are most important in ALS?

a)

Heart and lungs

b)

Biceps and triceps

c)

Quadriceps and hamstrings

d)

Deltoids and gluteals

35.

Which of the following is a symptom of ALS?

a)

Pathologic changes in the brain tissue

b)

Weakness of the voluntary muscles

c)

Unknown cause

d)

Slow onset

36.

Depression is relatively common in ALS because of the unrelenting progression of ______ and atrophy.

a)

muscle weakness

b)

joint pain

c)

skin lesions

d)

bone fractures

37.

What is a common cause of death in patients with respiratory muscle atrophy?

a)

Heart failure

b)

Respiratory infection and dysfunction

c)

Kidney failure

d)

Liver disease

38.

Which medication is mentioned as a treatment to slow down the progression of muscular atrophy?

a)

Ibuprofen

b)

Riluzole (Rilutek)

c)

Paracetamol

d)

Aspirin

39.

Guillain-Barre’ Syndrome (GBS) is a relatively rare immune-mediated polyneuropathy disease that affects the ________ nervous system.

a)

peripheral

b)

central

c)

autonomic

d)

enteric

40.

Which two viruses have been linked to Guillain-Barre’ Syndrome (GBS)?

a)

Influenza and HIV

b)

Cytomegalovirus and Epstein-Barr virus

c)

Herpes simplex and Varicella zoster

d)

Hepatitis B and C

41.

Guillain-Barre’ Syndrome (GBS) usually follows a simple viral respiratory infection or gastroenteritis in adults within 2 to 4 weeks.

a)

True

b)

False

42.

List two pathologic changes seen in Guillain-Barre’ Syndrome (GBS).

a)

Demyelination, inflammation, edema, and nerve root compression (any two)

b)

Neuronal hyperplasia and increased synaptic transmission

c)

Amyloid plaque formation and neurofibrillary tangles

d)

Cerebral atrophy and Lewy body accumulation

43.

Which of the following is NOT a treatment goal for Guillain-Barre’ Syndrome (GBS)?

a)

Maintain adequate ventilation

b)

Control pain adequately

c)

Increase muscle mass rapidly

d)

Prevent damage from aspiration

44.

What are the three phases of disease management mentioned in the notes? Fill in the blanks: 1. ______ phase 2. Static phase (plateau phase) 3. ______ phase

a)

1. Acute, 3. Rehabilitation

b)

1. Chronic, 3. Recovery

c)

1. Infectious, 3. Terminal

d)

1. Prodromal, 3. Decline

45.

Which phase is described as lasting for a few days up until 2 weeks, with motor loss and paresthesias no longer progressing?

a)

Static phase (plateau phase)

b)

Acute phase

c)

Recovery phase

d)

Prodromal phase

46.

Huntington Disease is characterized by which of the following?

a)

Abnormal movements

b)

Decline in intellectual capacity

c)

Emotional disturbances

d)

All of the above

47.

Huntington Disease is a genetic disorder caused by an abnormal gene on which chromosome?

a)

Short arm of chromosome 4

b)

Long arm of chromosome 7

c)

Short arm of chromosome 15

d)

Long arm of chromosome 21

48.

True or False: There is a known cure for Huntington Disease.

a)

True

b)

False

49.

Myasthenia Gravis is an autoimmune disease affecting which part of the body?

a)

Muscles (neuromuscular junction)

b)

Liver

c)

Kidneys

d)

Lungs

50.

What is the number one characteristic of Myasthenia Gravis?

a)

Ptosis (droopy eyelid)

b)

Tremor

c)

Bradycardia

d)

Jaundice

e)

Polyuria

51.

Which of the following is NOT a diagnostic method for Myasthenia Gravis?

a)

Tension test

b)

Blood test for antibodies to acetylcholine receptors

c)

Electrodiagnostic testing

d)

Urine analysis

52.

What is the treatment mentioned for Myasthenia Gravis?

a)

Anticholinesterase therapy

b)

Beta-blocker therapy

c)

Insulin therapy

d)

Calcium channel blocker therapy

53.

Anticholinesterase agents inactivate ________, a substance that prevents accumulation of acetylcholine at the neuromuscular junction. (Fill in the blank)

a)

acetylcholinesterase

b)

dopamine

c)

serotonin

d)

monoamine oxidase

54.

What is the effect of anticholinesterase agents on muscle strength?

a)

They permanently cure muscle weakness

b)

They temporarily increase muscle strength by allowing acetylcholine to work

c)

They decrease muscle strength

d)

They have no effect on muscle strength

55.

Which of the following is a possible treatment for myasthenia gravis?

a)

Thymus gland removal

b)

Liver transplant

c)

Kidney dialysis

d)

Bone marrow transplant

56.

Patients with myasthenia gravis may also get ________ as a treatment option.

a)

plasmapheresis

b)

chemotherapy

c)

insulin therapy

d)

radiation therapy

57.

Infection, surgery, and other physical and emotional stresses can precipitate a ________ and cause hospitalization in patients with myasthenia gravis. (Fill in the blank)

a)

myasthenic crisis

b)

thyroid storm

c)

asthmatic attack

d)

diabetic coma

58.

What is a key rehabilitation goal for patients and families dealing with myasthenia gravis?

a)

Complete isolation

b)

Education and support for independence

c)

Avoiding all physical activity

d)

No rehabilitation needed

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