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Digoxin toxicity

Total questions: 13

Worksheet time: 7mins

Name
Class
Date
1.

Non-cardiac symptoms of Digoxin toxicity include:

a)

a) CNS and GIT symptoms

b)

b) Respiratory and Renal symptoms

c)

c) Musculoskeletal and Dermatological symptoms

d)

d) Hepatic and Endocrine symptoms

2.

A key lab finding that strongly suggests severe Digoxin toxicity is:

a)

Hyponatremia

b)

Hyperkalemia

c)

Hypokalemia

d)

Hypercalcemia

3.

A patient is considered "clinically toxic" if their Digoxin level, drawn at least 6 hours

a)

above 0.5 ng/ml

b)

above 1 ng/ml

c)

above 2 ng/ml

d)

above 5 ng/ml

4.

...... and ...... can exacerbate CAS cardiotoxicity, even at "therapeutic" digoxin concentration:

a)

Hypocalcemia, Hypophosphatemia

b)

Hypernatremia, Hypocalcemia

c)

Hypomagnesemia, Hypernatremia

d)

Hyperkalemia, Hypokalemia

5.

Prior to the introduction of DSFab, ....... was used for supraventricular bradydysrhythmias, and ....... was used for ventricular tachydysrhythmias:

a)

Lidocaine, Amiodarone

b)

Atropine, phenytoin

c)

Lidocaine,Atropine

d)

Propranolol, Phenytoin

6.

Although ......... is beneficial in most hyperkalemia patients, in the setting of CAS poisoning, it is considered potentially

a)

Insulin

b)

Glucose

c)

Sodium Bicarbonate

d)

Calcium

7.

Gastrointestinal decontamination is rarely performed for digoxin poisoning because:

a)

It increases the risk of aspiration

b)

It is generally ineffective against CAS

c)

Rapid absorption of the drug

d)

can induce fatal arrhythmias

8.

When treating digoxin toxicity, multi-dose ...... can be administered 1g/kg body weight every 2-4 hours (to enhance elimination):

a)

Digoxin-specific Fab (DSFab)

b)

Kayexalate

c)

Activated Charcoal (AC)

d)

Sodium Bicarbonate

9.

Digoxin toxicity is often manifested by conduction problems between the:

a)

SA and AV nodes

b)

AV node and Bundle of His

c)

Bundle of His and Purkinje fibers

d)

SA node and atrial muscle

10.

In non-life-threatening cases, .......... administration generally should be withheld until the hypokalemia is corrected because the cardiotoxicity often resolves when the potassium is normalized:

a)

Atropine

b)

digoxin-specific Fab (DSFab)

c)

Activated Charcoal

d)

Phenytoin

11.

No. of vials of Digoxin-specific Fab = Total body load (mg) / ..... (mg/vial):

a)

0.25

b)

0.5

c)

1

d)

0.1

12.

In the formula for calculating DSFab dosage based on serum levels, what does "SDC" represent?

a)

Serum Digoxin Concentration

b)

Standard Dose Calculation

c)

Serum Dosing Constant

d)

Severe Digoxin Cardiotoxicity

13.

A toxic serum concentration (level) used for calculating DSFab dosage in an acute ingestion for an adult is cited as ......... , and for a child as ........ .

a)

4 ng/ml (adult), 10 ng/ml (child)

b)

5 ng/ml (adult), 2 ng/ml (child)

c)

10 ng/ml (adult), 4 ng/ml (child)

d)

2 ng/ml (adult), 1 ng/ml (child)