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WorksheetsDigoxin toxicity
Total questions: 13
Worksheet time: 7mins
Non-cardiac symptoms of Digoxin toxicity include:
a) CNS and GIT symptoms
b) Respiratory and Renal symptoms
c) Musculoskeletal and Dermatological symptoms
d) Hepatic and Endocrine symptoms
A key lab finding that strongly suggests severe Digoxin toxicity is:
Hyponatremia
Hyperkalemia
Hypokalemia
Hypercalcemia
A patient is considered "clinically toxic" if their Digoxin level, drawn at least 6 hours
above 0.5 ng/ml
above 1 ng/ml
above 2 ng/ml
above 5 ng/ml
...... and ...... can exacerbate CAS cardiotoxicity, even at "therapeutic" digoxin concentration:
Hypocalcemia, Hypophosphatemia
Hypernatremia, Hypocalcemia
Hypomagnesemia, Hypernatremia
Hyperkalemia, Hypokalemia
Prior to the introduction of DSFab, ....... was used for supraventricular bradydysrhythmias, and ....... was used for ventricular tachydysrhythmias:
Lidocaine, Amiodarone
Atropine, phenytoin
Lidocaine,Atropine
Propranolol, Phenytoin
Although ......... is beneficial in most hyperkalemia patients, in the setting of CAS poisoning, it is considered potentially
Insulin
Glucose
Sodium Bicarbonate
Calcium
Gastrointestinal decontamination is rarely performed for digoxin poisoning because:
It increases the risk of aspiration
It is generally ineffective against CAS
Rapid absorption of the drug
can induce fatal arrhythmias
When treating digoxin toxicity, multi-dose ...... can be administered 1g/kg body weight every 2-4 hours (to enhance elimination):
Digoxin-specific Fab (DSFab)
Kayexalate
Activated Charcoal (AC)
Sodium Bicarbonate
Digoxin toxicity is often manifested by conduction problems between the:
SA and AV nodes
AV node and Bundle of His
Bundle of His and Purkinje fibers
SA node and atrial muscle
In non-life-threatening cases, .......... administration generally should be withheld until the hypokalemia is corrected because the cardiotoxicity often resolves when the potassium is normalized:
Atropine
digoxin-specific Fab (DSFab)
Activated Charcoal
Phenytoin
No. of vials of Digoxin-specific Fab = Total body load (mg) / ..... (mg/vial):
0.25
0.5
1
0.1
In the formula for calculating DSFab dosage based on serum levels, what does "SDC" represent?
Serum Digoxin Concentration
Standard Dose Calculation
Serum Dosing Constant
Severe Digoxin Cardiotoxicity
A toxic serum concentration (level) used for calculating DSFab dosage in an acute ingestion for an adult is cited as ......... , and for a child as ........ .
4 ng/ml (adult), 10 ng/ml (child)
5 ng/ml (adult), 2 ng/ml (child)
10 ng/ml (adult), 4 ng/ml (child)
2 ng/ml (adult), 1 ng/ml (child)
