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DNA Replication, Mitosis, and Cancer

Total questions: 35

Worksheet time: 24mins

Name
Class
Date
1.
The enzyme that unzips the DNA to prepare for replication
a)
helicase
b)
replicase
c)
polymerase
d)
synthase
2.
DNA replication results in two DNA molecules,
a)
each one with two original strands
b)
each one with two new strands
c)
each one with one new strand and one original strand
d)
one with two new strands and the other with two original strands
3.

Adds nucleotides to the newly synthesized strand of DNA

a)

DNA polymerase

b)

Okazaki

c)

Helicase

d)

Ligase

4.

DNA replication creates two strands of DNA from one. If pink is parental DNA and blue is new DNA - which picture demonstrates the accepted model of DNA replication after the SECOND replication cycle?

a)
b)
c)
d)
5.

The picture below shows an enzyme unwinding and unzipping DNA.

​

​What is the name of this enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

6.

Many enzymes are involved in DNA replication. Which is the correct order of enzymes involved in DNA replication from beginning to end?

a)

Helicase, DNA primase, DNA polymerase, Ligase

b)

RNA primase, Helicase, DNA polymerase, Ligase

c)

Helicase, RNA primase, DNA polymerase, Ligase

d)

DNA primase, Helicase, RNA polymerase, Ligase

7.
In what phase of the cell cycle does DNA replication take place?
a)
G1
b)
S
c)
G2
d)
M
8.

Which enzyme fixes the Okazaki fragments in the lagging strand?

a)

Helicase

b)

Polymerase

c)

Ligase

d)

Primerase

9.
If a strand reads:
3' A A A T T T C 5'
The matching strand would read...
a)
5' T T T A A A G 3'
b)
3' T T T A A A G 5'
c)
5' A A A T T T C 3'
d)
3' U U U A A A G 5'
10.
This picture is illustrating the ____ nature of DNA.
a)
anti-parallel
b)
deoxyribosic
c)
helical
d)
radioactive
11.

The enzyme that splits open the DNA creates what's called a fork - where the DNA separates into the lagging strand and the ______ strand.

a)

leading

b)

leveraging

c)

Okazaki

d)

ligase

12.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

13.

Which letter in the picture below depicts the lagging strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

14.

Okazaki fragments appear on which strand of DNA during DNA replication?

a)

lagging

b)

leading

15.
A picture of a cell's chromosomes is called a
a)
gene diagram
b)
chromogram
c)
karyotype
d)
genotype
16.
Refer to the illustration above. The cell in diagram 1 is in 
a)
prophase 
b)
metaphase
c)
telophase
d)
anaphase
17.
Refer to the illustration above. Mitosis begins with the stage drawn in diagram 
a)
1
b)
2
c)
3
d)
4
18.
A Goat has 60 chromosomes in its body cells.  What is the haploid number?
a)
60
b)
30
c)
100
d)
120
19.
A human has 46 chromosomes in their body cells.  What is the haploid number?
a)
46
b)
92
c)
23
d)
12
20.
Mitosis produces cells with haploid or diploid number of chromosomes?
a)
Haploid
b)
Diploid
21.
How many cells are produced in Mitosis?
a)
1
b)
2
c)
3
d)
4
22.
Are the cells in Mitosis identical or unique?
a)
Identical 
b)
Unique
c)
It's random
23.
In which phase do chromosomes move away to opposite sides of the cell?
a)
Prophase
b)
Metaphase
c)
Anaphase
d)
Telophase
24.
In mitosis, the end product is...
a)
2 haploid cells
b)
2 diploid cells
c)
4 haploid cells
d)
4 diploid cells
25.
This phase of mitosis lines the chromosomes in the middle of the cell.
a)
Anaphase
b)
Prophase
c)
Metaphase
d)
Telophase
26.
What is the gender of the individual whose karyotype is seen in the image?
a)
Male
b)
Female
27.
A pair of identical chromosomes shown in a karyotype, one inherited from mom, and one inherited from dad are called
a)
sister chromotids
b)
centromeres
c)
homologous chromosomes
d)
autosomes
28.

Which of these is a difference between plant cytokinesis and animal cytokinesis?

a)

animal cells make cleavage furrows, plant cells make cell plates

b)

animal cells divide from the outside in, plant cells divide from the inside out

c)

plant cells can't divide like animal cells because they have a cell wall

d)

All of these are differences between plant and animal cytokinesis

29.

What happens when a cell loses control of its cell cycle?

a)

Cancer

b)

DNA replication

c)

Transcription

d)

Translation

30.

Cancer is defined as the

a)

uncontrolled division of mutated cells

b)

normal division of cells

c)

normal DNA replication

d)

abnormal ATP synthesis

31.

A benign tumor differs from a malignant tumor in that a benign tumor

a)

is cancerous

b)

spreads from the original site

c)

does not metastasize

d)

never causes health problems

32.

The invasion of the bloodstream by a malignant cell that takes up residence in a new location is called.

a)

Metastasis

b)

Metaphase

c)

Benign tumor relocation

d)

cancer relocation

33.

Any substance that is known to cause cancer is called a

a)

Pathogen

b)

Biopsy

c)

Carcinogen

d)

Retrovirus

34.

Which of the following are known carcinogens?

CHOOSE ALL THAT APPLY!

a)

UV rays

b)

X-rays

c)

Certain viruses

d)

Eating fruits

e)

Smoking

35.

Common treatments for cancer include:

CHOOSE ALL THAT APPLY!

a)

chemotherapy

b)

immunotherapy

c)

radiation therapy

d)

psychotherapy

e)

multivitamins

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