Worksheetspretes biokimia 2.2
Total questions: 10
Worksheet time: 5mins
Which of the following best describes the main function of acetylcholine (ACh) in the nervous system?
Inhibits synaptic transmission in the CNS
Acts as a major excitatory neurotransmitter at neuromuscular junctions
Enhances dopamine release in the basal ganglia
Inhibits cardiac muscle contraction
Stimulates serotonin reuptake
Acetylcholine is synthesized in the presynaptic terminal from:
Tyrosine and dopa decarboxylase
Choline and acetyl-CoA via choline acetyltransferase
Tryptophan and monoamine oxidase
Glutamate and choline esterase
Serine and acetyl-CoA via catechol-O-methyltransferase
Which enzyme is primarily responsible for the degradation of acetylcholine in the synaptic cleft?
Monoamine oxidase (MAO)
Catechol-O-methyltransferase (COMT)
Choline acetyltransferase (ChAT)
Acetylcholinesterase (AChE)
Tyrosine hydroxylase
Which of the following correctly matches a catecholamine with its major site of synthesis?
Dopamine – adrenal medulla
Norepinephrine – substantia nigra
Epinephrine – adrenal medulla
Dopamine – sympathetic postganglionic neuron
Epinephrine – hypothalamus
Dopamine is converted to norepinephrine by the enzyme:
Monoamine oxidase
Tyrosine hydroxylase
Dopamine β-hydroxylase
Dopa decarboxylase
Catechol-O-methyltransferase
Serotonin (5-HT) is synthesized from which amino acid?
Phenylalanine
Tyrosine
Tryptophan
Histidine
Glutamine
The main neurotransmitter at the neuromuscular junction in the somatic nervous system is:
Norepinephrine
Dopamine
Acetylcholine
GABA
Serotonin
In the autonomic nervous system, norepinephrine is primarily released by:
Parasympathetic preganglionic neurons
Sympathetic postganglionic neurons
Somatic motor neurons
Sensory afferent fibers
Parasympathetic postganglionic neurons
Decreased dopamine activity in the substantia nigra is mainly associated with which disorder?
Alzheimer’s disease
Depression
Parkinson’s disease
Schizophrenia
Anxiety disorder
Which of the following vitamins is essential for maintaining myelin sheath integrity and neurotransmitter synthesis?
Vitamin A
Vitamin B complex
Vitamin C
Vitamin D
Vitamin K
