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NAPCON JAIPUR QUIZ 3

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.
In IPF, the MUC5B promoter variant confers:
a)
Worse survival
b)
Faster disease progression
c)
Improved survival but increased susceptibility to disease
d)
Resistance to antifibrotic therapy
2.
In Langerhans cell histiocytosis, the diagnostic marker on immunohistochemistry is:
a)
CD1a and Langerin (CD207)
b)
S100 only
c)
CD68
d)
TTF-1
3.
In nintedanib-treated patients with IPF, the most common mechanism of diarrhea is:
a)
Pancreatic insufficiency
b)
VEGF receptor blockade causing mucosal injury
c)
Microbial dysbiosis
d)
Bile acid malabsorption
4.
In PAH, the response to acute vasodilator testing (with nitric oxide) is defined as:
a)
↓ mPAP by ≥10 mmHg to <40 mmHg
b)
↓ mPAP by ≥20%
c)
↓ mPAP ≥10 mmHg to ≤40 mmHg with unchanged/increased CO
d)
↓ PVR >50%
5.
In post-COVID pulmonary fibrosis, the predominant radiologic pattern is:
a)
Centrilobular nodules
b)
Organizing pneumonia evolving to fibrotic NSIP
c)
UIP
d)
Bronchiectasis only
6.
In pulmonary arterial hypertension (PAH), which signaling pathway is most implicated?
a)
Wnt/β-catenin
b)
BMPR2–Smad pathway dysregulation
c)
MAP kinase overactivation
d)
PI3K inhibition
7.
Which of the following is not a biologic used in severe asthma?
a)
Mepolizumab
b)
Dupilumab
c)
Omalizumab
d)
Montelukast
8.
In asthma, FeNO levels are lowest in which phenotype?
a)
Eosinophilic asthma
b)
Aspirin-sensitive asthma
c)
Neutrophilic asthma
d)
Allergic asthma
9.
Time taken by blood to traverse pulmonary capillaries at rest in seconds
a)
1
b)
0.1
c)
0.3
d)
0.75
10.
Compared to gas ventilated lung, liquid ventilated lung
a)
Has reduced airway resistance
b)
Has increased residual volume
c)
Is more compliant
d)
Has more hysteresis