WorksheetsEndocrine System
Total questions: 59
Worksheet time: 31mins
communication in the body through endocrine system
via hormones carried by body fluids
via nerve impulse transmitted through neurons
slower acting, longer lasting
fast acting, short lasting
communication in the body through endocrine system
via hormones carried by body fluids
via nerve impulse transmitted through neurons
slower acting, longer lasting
fast acting, short lasting
secrete hormones directly into blood
small organs distributed throughout the body that produces hormones
highly vascularized
chemical messengers in blood
act of specific targets
affects metabolism of cells and tissues
hormones can only affect those cells with
how many cells can a hormone target?
2k to 100k
3k to 100k
2k to 200k
most endocrine organs are surrounded by _____ allowing hormones easy access to blood
fenestrated myothelium
fenestrated epithelium
fenestrated endothelium
large water-soluble hormones require receptor mediated ____ to get out of circulation
transcytosis
most hormones are regulated by a
negative feedback mechanisms
which chemicals are lipid-soluble?
Amino Acids
Protein Hormones
Steroid Hormones
which chemicals are water-soluble?
Amino Acids
Protein Hormones
Steroid Hormones
enter cells, and change gene expression
new proteins alter cell's activity
protein bound
Amino Acids
Protein Hormones
Steroid Hormones
bind cell membrane receptors, and use second messengers inside produce all the effects.
Amino Acids
Protein Hormones
Steroid Hormones
which is the "releasing hormones" that directs anterior pituitary
Hypothalamus
Pituitary Gland
Adrenal Cortex
controlled via hypophyseal portal system
two capillary networks attached by portal veins
anterior pituitary
posterior pituitary
hypothalamus
"master gland"
releases "tropic hormones"
anterior pituitary
posterior pituitary
hypothalamus
blood vessel system that directly connects hypothalamus and anterior pituitary
allows sending of hormones DIRECTLY
hypophyseal portal system
what are tropic hormones?
target ovaries & testes
for follicle growth (estrogen release)
for sperm production
Follicle Stimulating Hormone (FSH)
Luteinizing Hormone (LH)
Adrenocorticotropic Hormone (ACTH)
Thyroid Stimulating Hormone (TSH)
Growth Hormone
(GH)
target ovaries & testes
stimulates ovulation & testosterone
Follicle Stimulating Hormone (FSH)
Luteinizing Hormone (LH)
Adrenocorticotropic Hormone (ACTH)
Thyroid Stimulating Hormone (TSH)
Growth Hormone
(GH)
target adrenal cortex
to stimulate cortisol & estrogen/testosterone secretion
Follicle Stimulating Hormone (FSH)
Luteinizing Hormone (LH)
Adrenocorticotropic Hormone (ACTH)
Thyroid Stimulating Hormone (TSH)
Growth Hormone
(GH)
target thyroid gland
to stimulate T3 & T4
Prolactin
Luteinizing Hormone (LH)
Adrenocorticotropic Hormone (ACTH)
Thyroid Stimulating Hormone (TSH)
Growth Hormone
(GH)
target most body cells
to stimulate growth & division
Prolactin
Luteinizing Hormone (LH)
Adrenocorticotropic Hormone (ACTH)
Thyroid Stimulating Hormone (TSH)
Growth Hormone
(GH)
not a tropic hormone
target breast
stimulates breast development and milk production
Prolactin
Luteinizing Hormone (LH)
Adrenocorticotropic Hormone (ACTH)
Thyroid Stimulating Hormone (TSH)
Growth Hormone
(GH)
GH is most abundant in which part of the body
does not synthesize (make) hormones
secretes hormones produced in hypothalamus via hypophyseal tracts
target uterus and breast
causes smooth muscle contraction during delivery
milk ejection
target kidney
stimulates reabsorption of water
low urine production and sweating
increased BP
when does osmoreceptors in hypothalamus gets triggered to release ADH
Osmoreceptors are triggered by high osmotic pressure
why do we experience excessive urination and rapid dehydration when drinking alcohol?
Alcohol inhibit vasopressin, leading to increased water excretion by the kidneys.
two lobes connected by an isthmus
produces thyroid hormones & calcitonin
thyroid gland
adrenal glands
pancreas
parathyroid gland
surrounded follicles
produce T3 & T4
follicular cells
parafollicular cells
found between follicles
produce calcitonin
follicular cells
parafollicular cells
storage form of thyroid hormone precursors found in thyroid follicles produced by follicular cells
only released when need
Colloid
a form of colloid
more abundant and longer-lasting
converted to T3 inside the cell
circulating
a form of colloid
4x more potent than T4
cell activating hormone
target most body cells
↑ metabolic rate
↑ body temp
↑ protein synthesis
Thyroid hormones
hyperthyroidism causes
weight loss, muscle tremors, excessive perspiration (sweating), and nervousness
due to excess thyroid hormones
due to thyroid hormones deficiency
produced by parafollicular cells
target bone
lowers blood calcium deposition in bone
antagonist to parathyroid hormone
4-8 pea sized glands embedded in the thyroid gland
parathyroid hormone
increase calcium reabsorption, stimulating bone resorption, and promoting vitamin D activation
responsible for insulin production in the pancreas
regulates sodium levels in the blood and affects blood pressure
decreases calcium levels by promoting excretion in the kidneys
superior pole of kidneys
role in body body metabolism, bp, and stress response
target kidneys
stimulates Na and water reabsorption in the kidney
K secretion
main stress hormone of the body
what are the effects of cortisol?
↑ blood glucose
↑ BP due to vasoconstriction
↑ connective tissue production
↑ protein and lipid breakdown
what is hypocortisolism?
manifestation: weakness in limbs, obesity, moon face, facial redness
to an excess of adrenal hormones.
condition of high cortisol levels.
type of adrenal gland tumor.
condition of low cortisol levels.
sex hormones produced by adrenal cortex
usually have little significance
aldosterone
gonadocorticoids
cortisol
Progestin
hormones produced by adrenal cortex
10% of mass of adrenal gland
released in times of stress to enhance and prolong SNS
adrenal medulla
adrenal cortex
which cells in adrenal medulla produce catecholamines such as norepinephrine and epinephrine?
posterior to stomach
mixed gland
99% exocrine acini
where is endocrine cells of pancreas found?
islets of Langerhans
acini
ducts of the pancreas
stomach lining adjacent to the pancreas
acts on almost all cells of body
increased glucose uptake
insulin
glucagon
what are the roles of insulin in fat, protein, and glucose?
reduces glycogen production
glucose uptake
promotes fat storage
enhances protein synthesis
promotes gluconeogenesis
primarily affects the liver
antagonist of insulin
why is glucagon considered an antagonist of insulin?
promotes glycogen conversion back to glucose and release to blood
both raise blood glucose levels equally
promotes fat storage, while insulin promotes fat breakdown
decreases blood glucose levels, while insulin increases them.
Type 1 Diabetes means
lack of insulin
state of insulin resistance
insulin is overproduced
Type 2 Diabetes means
lack of insulin
state of insulin resistance
insulin is overproduced
