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PRINCIPLES OF INHERITANCE

Total questions: 79

Worksheet time: 40mins

Name
Class
Date
1.

Mendel is known as the father of genetics because he worked on:

a)

Pea plant

b)

Maize

c)

Drosophila

d)

Wheat

2.

A diploid organism has 8 chromosomes. The number of chromosomes in its gametes will be:

a)

2

b)

4

c)

8

d)

16

3.

Test cross is a cross between F1 hybrid and:

a)

Dominant parent

b)

Recessive parent

c)

Any parent

d)

Heterozygous parent

4.

Incomplete dominance was observed by Mendel’s successors in:

a)

Pea

b)

Snapdragon

c)

Maize

d)

Wheat

5.

In dihybrid cross, the phenotypic ratio is:

a)

1:2:1

b)

9:3:3:1

c)

3:1

d)

2:1

6.

The chromosome theory of inheritance was proposed by:

a)

Darwin

b)

Morgan

c)

Sutton and Boveri

d)

Mendel

7.

A gene located on X chromosome is called:

a)

Holandric

b)

Autosomal

c)

Sex-linked

d)

Y-linked

8.

A person with genotype IAIO has blood group:

a)

A

b)

B

c)

AB

d)

O

9.

Sickle-cell anaemia is caused by:

a)

Substitution of amino acid

b)

Deletion

c)

Inversion

d)

Duplication

10.

The law of segregation is also known as:

a)

Law of purity of gametes

b)

Law of dominance

c)

Law of independent assortment

d)

Law of assortment

11.

Haemophilia is:

a)

Autosomal recessive

b)

Sex-linked recessive

c)

Sex-linked dominant

d)

Autosomal dominant

12.

Eye colour in Drosophila shows:

a)

Mendelian inheritance

b)

Sex-linked inheritance

c)

Multiple allelism

d)

Polygenic inheritance

13.

Discontinuous variation is caused by:

a)

Polygenes

b)

Environment

c)

Multiple alleles

d)

Single gene

14.

Polygenic inheritance results in:

a)

Discontinuous variation

b)

Continuous variation

c)

Independent assortment

d)

Epistasis

15.

A colour-blind woman marries a normal man. Sons will be:

a)

All colour blind

b)

Half colour blind

c)

None colour blind

d)

All normal

16.

Barr body is present in:

a)

Male

b)

Female

c)

Both

d)

None

17.

The number of linkage groups in humans is:

a)

23

b)

24

c)

46

d)

22

18.

Recombination is least in:

a)

Linked genes

b)

Unlinked genes

c)

Sex-linked genes

d)

Autosomal genes

19.

Phenylketonuria is caused due to defect in:

a)

Hormone

b)

Enzyme

c)

Protein

d)

Vitamin

20.

A dihybrid F1 plant is:

a)

Homozygous

b)

Heterozygous

c)

Partially dominant

d)

Recessive

21.

When two alleles do not exhibit dominance, it results in:

a)

Multiple alleles

b)

Codominance

c)

Epistasis

d)

Polygenes

22.

ABO blood group system exhibits:

a)

Polygenic inheritance

b)

Incomplete dominance

c)

Multiple allelism

d)

Sex linkage

23.

The physical location of a gene on a chromosome is called:

a)

Allele

b)

Locus

c)

Centromere

d)

Chromatid

24.

Crossing over occurs at:

a)

Centromere

b)

Synaptonemal complex

c)

Telomere

d)

Spindle fibre

25.

Aneuploidy is caused by:

a)

Non-disjunction

b)

Crossing over

c)

Mutation

d)

Independent assortment

26.

Turner's syndrome has karyotype:

a)

XXY

b)

XO

c)

XXX

d)

XY

27.

Klinefelter's syndrome individuals are:

a)

XO

b)

XXY

c)

XYY

d)

XXX

28.

Pedigree analysis is used to study:

a)

Bacteria

b)

Plants

c)

Humans

d)

Viruses

29.

Which shows codominance?

a)

Sickle-cell gene

b)

IA and IB alleles

c)

Eye colour

d)

Skin colour

30.

A man with normal vision marries a colour-blind woman. Daughters will be:

a)

All normal

b)

All carriers

c)

All colour blind

d)

Half colour blind

31.

Sickle-cell trait genotype is:

a)

HbAHbA

b)

HbSHbS

c)

HbAHbS

d)

HbSHbS

32.

The tallness gene (T) is dominant over:

a)

Tall gene

b)

Dwarf gene

c)

Recessive gene

d)

Co-dominant gene

33.

A human with blood group O has genotype:

a)

IAIO

b)

IOIO

c)

IBIO

d)

IAIB

34.

The scientist who discovered linkage was:

a)

Morgan

b)

Mendel

c)

Sutton

d)

Bateson

35.

Independent assortment occurs in:

a)

Linked genes

b)

Unlinked genes

c)

Identical genes

d)

None

36.

Genes controlling different traits assort independently due to:

a)

Meiosis

b)

Mitosis

c)

Mutation

d)

DNA replication

37.

The phenotypic ratio in incomplete dominance is:

a)

3:1

b)

1:2:1

c)

9:3:3:1

d)

2:1

38.

Eye colour in humans is an example of:

a)

Monogenic inheritance

b)

Codominance

c)

Polygenic inheritance

d)

Sex-linked trait

39.

Identical genes are called:

a)

Alleles

b)

Homozygous

c)

Heterozygous

d)

Genotype

40.

Section B: Fill in the blanks. Mendel’s monohybrid ratio is ______.

a)

1:1

b)

3:1

c)

9:3:3:1

d)

1:2:1

41.

Section B: Fill in the blanks. The alternative forms of a gene are called ______.

a)

alleles

b)

loci

c)

traits

d)

genotypes

42.

Section B: Fill in the blanks. The physical expression of a gene is called ______.

a)

genotype

b)

phenotype

c)

allele

d)

karyotype

43.

Section B: Fill in the blanks. ABO blood groups are an example of ______.

a)

multiple alleles

b)

epistasis

c)

pleiotropy

d)

crossing over

44.

Section B: Fill in the blanks. Sex-linked genes are present on ______ chromosomes.

a)

X

b)

Y

c)

autosomes

d)

chloroplast

45.

Section B: Fill in the blanks. Independent assortment occurs during ______.

a)

mitosis

b)

meiosis

c)

fertilization

d)

DNA replication

46.

Section B: Fill in the blanks. A cross between F1 and recessive parent is called ______.

a)

back cross

b)

test cross

c)

reciprocal cross

d)

dihybrid cross

47.

Section B: Fill in the blanks. Turner syndrome individuals have ______ sex chromosomes.

a)

XO

b)

XXY

c)

XXX

d)

XY

48.

Section B: Fill in the blanks. Sickle cell anaemia is caused by a change in ______.

a)

one amino acid

b)

chromosome number

c)

codon count

d)

entire gene deletion

49.

Section B: Fill in the blanks. Genes located on the same chromosome are called ______.

a)

linked genes

b)

allelic genes

c)

complementary genes

d)

lethal genes

50.

Section B: Fill in the blanks. Eye colour in Drosophila is ______ linked.

a)

sex

b)

autosomal

c)

Y

d)

mitochondrial

51.

Section B: Fill in the blanks. Continuous variation is produced by ______.

a)

polygenic inheritance

b)

single-gene mutation

c)

complete dominance

d)

chromosomal deletion

52.

Section B: Fill in the blanks. A carrier female for colour-blindness has genotype ______.

a)

XCXc

b)

XcXc

c)

XY

d)

XCY

53.

Section B: Fill in the blanks. Colour blindness is ______ linked.

a)

X

b)

Y

c)

autosomal

d)

mitochondrial

54.

Section B: Fill in the blanks. Phenylketonuria is an ______ disorder.

a)

autosomal recessive

b)

autosomal dominant

c)

X-linked dominant

d)

mitochondrial

55.

Section B: Fill in the blanks. A Barr body is an ______ chromosome.

a)

inactivated X

b)

duplicated Y

c)

deleted autosome

d)

supernumerary mitochondrial

56.

Section B: Fill in the blanks. Crossing over occurs in ______ stage of meiosis.

a)

zygotene

b)

pachytene

c)

diplotene

d)

metaphase I

57.

Section B: Fill in the blanks. The F2 generation of dihybrid cross gives ______ ratio.

a)

3:1

b)

1:2:1

c)

9:3:3:1

d)

1:1

58.

Section B: Fill in the blanks. Human males are the ______ sex.

a)

homogametic

b)

heterogametic

c)

hemizygous-only

d)

haploid

59.

Section B: Fill in the blanks. Recessive allele expresses only in ______ condition.

a)

homozygous

b)

heterozygous

c)

hemizygous

d)

codominant

60.

Section C: True or False. Mendel worked on pea plants.

a)

True

b)

False

61.

State whether the statement is True or False: The law of segregation states that genes blend during gamete formation.

a)

True

b)

False

62.

State whether the statement is True or False: A carrier female for haemophilia shows symptoms.

a)

True

b)

False

63.

State whether the statement is True or False: Codominance means both alleles express equally.

a)

True

b)

False

64.

State whether the statement is True or False: Colour blindness is Y-linked.

a)

True

b)

False

65.

State whether the statement is True or False: Linked genes show more recombination.

a)

True

b)

False

66.

State whether the statement is True or False: Crossing over increases genetic variation.

a)

True

b)

False

67.

State whether the statement is True or False: XO individuals are infertile.

a)

True

b)

False

68.

State whether the statement is True or False: Incomplete dominance results in 1:2:1 ratio.

a)

True

b)

False

69.

State whether the statement is True or False: All mutations are harmful.

a)

True

b)

False

70.

State whether the statement is True or False: Polygenic traits show continuous variation.

a)

True

b)

False

71.

State whether the statement is True or False: IA and IB exhibit codominance.

a)

True

b)

False

72.

State whether the statement is True or False: Turner's syndrome affects males.

a)

True

b)

False

73.

State whether the statement is True or False: Homozygous dominant and heterozygous individuals show same phenotype.

a)

True

b)

False

74.

State whether the statement is True or False: Sickle-cell anaemia is due to a point mutation.

a)

True

b)

False

75.

State whether the statement is True or False: Females are homogametic in humans.

a)

True

b)

False

76.

State whether the statement is True or False: Multiple alleles occur in a single individual.

a)

True

b)

False

77.

State whether the statement is True or False: Epistasis is interaction between two genes.

a)

True

b)

False

78.

State whether the statement is True or False: Genetic disorders always follow Mendelian inheritance.

a)

True

b)

False

79.

State whether the statement is True or False: Genes located close to each other show linkage.

a)

True

b)

False

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