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WorksheetsUTEP Pharm ISBP Physiology and function of the GI system
Total questions: 74
Worksheet time: 39mins
The digestive system can be divided into the
Alimentary Canal
Accessory Organs
Both
this assists in digestion and consists of organs such as the gallbladder and pancreas
Alimentary Canal
Accessory Organs
Continuous, hollow, muscular tube (about 30 feet long!).
Alimentary Canal
Accessory Organs
Innermost layer. Consists of surface epithelium, lamina propria (connective tissue), a layer of smooth muscle.
The mucosa
The submucosa
The muscularis externa
The serosa
Peristalsis
Consists of more connective tissue that holds mucosa-associated glands, blood vessels, nerve endings, and lymphatic vessels.
The mucosa
The submucosa
The muscularis externa
The serosa
Peristalsis
Consists of inner (circular) and outer (longitudinal) smooth muscle layers. Physically move food down alimentary canal.
The mucosa
The submucosa
The muscularis externa
The serosa
Peristalsis
Outermost layer. Consists of the visceral peritoneum, parietal peritoneum and mesentery. Lining that makes up abdominopelvic cavity.
The mucosa
The submucosa
The muscularis externa
The serosa
Peristalsis
Involuntary wave-like constriction and relaxation of the muscles that propel food down alimentary canal.
The mucosa
The submucosa
The muscularis externa
The serosa
Peristalsis
Boney attachments (e.g., hyoid bone) & fold of mucus membrane (lingual frenulum) that holds it to floor, limits movements.
Tongue
Vestibule
Tonsils
Space between lips/cheeks and teeth/gums.
Tongue
Vestibule
Tonsils
Provide first line of defense for alimentary canal. Part of lymphatic immune system. Trap bacteria, release antibodies.
Tongue
Vestibule
Tonsils
_________________ is contracted to allow for breathing while chewing
upper esophageal sphincter
epiglottis
cardioesophageal sphincter
Lesser esophageal sphincter
The _________________ covers the trachea and the upper esophageal sphincter opens to allow food to enter the alimentary canal.
upper esophageal sphincter
epiglottis
cardioesophageal sphincter
Lesser esophageal sphincter
The __________________________ opens and food enters the stomach.
upper esophageal sphincter
epiglottis
cardioesophageal sphincter
Lesser esophageal sphincter
Stomach
Located on the left side of abdominal cavity.
Located on the right side of abdominal cavity.
Stomach
Food enters from esophagus via the cardia
Food enters from esophagus via the duodenum
Stomach:
top to bottom
Fundus, body, pyloric antrum, pyloric sphincter
body, fundus, pyloric sphincter, pyloric antrum
Stomach
When empty, folds on self and mucosa retreats into rugae (folds of the stomach).
When full, folds on self and mucosa retreats into rugae (folds of the stomach).
rugae are
folds of the stomach.
the smooth parts of the stomach.
Most digestive activity occurs in the ________ region of the stomach and is chemical and mechanical in nature.
pyloric
fundus
body
cardia
Muscularis Externa:
Stomach contains _____ muscle layer (oblique layer) that allows stomach to churn and physically break down food.
1st
2nd
3rd
4th
Muscularis Externa:
Stomach contains 3rd muscle layer (________________) that allows stomach to churn and physically break down food.
longitudinal layer
circular layer
oblique layer
the longitudinal layer, circular layer, and oblique layer make up
muscularis externa
muscularis interna
Gastric glands contain:
Surface epithelial cells
Mucous neck cells
Chief cells
Parietal cells
Enteroendocrine cells
secrete mucus that is bicarbonate rich and protects it from acid and digestive enzymes.
Surface epithelial cells
Mucous neck cells
Chief cells
Parietal cells
Enteroendocrine cells
secrete acidic mucus
Surface epithelial cells
Mucous neck cells
Chief cells
Parietal cells
Enteroendocrine cells
secrete digesting enzymes.
Surface epithelial cells
Mucous neck cells
Chief cells
Parietal cells
Enteroendocrine cells
secrete hydrochloric acid (HCl). HCl breaks down food and activates digestive enzymes.
Surface epithelial cells
Mucous neck cells
Chief cells
Parietal cells
Enteroendocrine cells
secrete local hormones that regulate digestion.
Surface epithelial cells
Mucous neck cells
Chief cells
Parietal cells
Enteroendocrine cells
The _________ intestine has three subdivisions: Duodenum (5%), jejunum (40%), and ileum (60%).
small
large
Ileum connects small intestine to large intestine at ileocecal valve.
true
false
Primary function of the _________ intestine is nutrient absorption via villi (fingerlike projections that increase surface area)
small
large
Five subdivisions: cecum, appendix, colon, rectum, and anal canal.
small intestine
large intestine
Primary function of _________ intestine is water absorption and elimination of food residue as feces.
small
large
Hangs from cecum. Usually twisted, which increases chances of bacteria accumulation and inflammation
appendix
rectum
colon
Colon: Includes
ascending colon->right colic flexure->transverse colon->left colic flexure-> descending colon->sigmoid colon.
ascending colon->left colic flexure->sigmoid colon->right colic flexure-> descending colon->transverse colon.
descending colon->right colic flexure->transverse colon->left colic flexure-> ascending colon->sigmoid colon.
____________ has an internal sphincter (smooth muscle, involuntary) and external sphincter (skeletal muscle, voluntary).
Anal canal
Colon
Cecum
smooth muscle, involuntary
internal sphincter
external sphincter
skeletal muscle, voluntary
internal sphincter
external sphincter
An active, voluntary process.
Ingestion
Mechanical breakdown
Propulsion
Digestion
Absorption
Physical fragmentation of food into smaller particles. Chewing in mouth and churning in the stomach are examples.
Ingestion
Mechanical breakdown
Propulsion
Digestion
Absorption
Propelled of food from one organ to the next. Swallowing in pharynx and peristalsis (involuntary waves of contraction and relaxation) in alimentary canal are two examples.
Ingestion
Mechanical breakdown
Propulsion
Digestion
Absorption
Large food molecules are chemically broken down to their building blocks by enzymes.
Defecation
Mechanical breakdown
Propulsion
Digestion
Absorption
Excretion of food waste from body.
Defecation
Mechanical breakdown
Propulsion
Digestion
Absorption
Mainly metabolic and regulatory roles (e.g., glucose release); however, also aids in digestion (particularly the breakdown of fat) by producing bile, an alkaline compound that includes bile salts, cholesterol, phospholipids, and electrolytes.
Liver
Gallbladder
Pancreas
Hepatopancreatic ampulla
Stores bile (digestive fluid) produced by the liver.
Liver
Gallbladder
Pancreas
Hepatopancreatic ampulla
Secretes important digestive hormones, such as insulin (an endocrine function).
Delivered to the Duodenum through the pancreatic duct.
Liver
Gallbladder
Pancreas
Hepatopancreatic ampulla
Juncture of pancreatic and bile duct. Fluids released into duodenum via duodenal papilla.
Liver
Gallbladder
Pancreas
Hepatopancreatic ampulla
which division of the nervous system activates:
Stimulates digestive activity
stimulates gall bladder
Parasympathetic
Sympathetic
which division of the nervous system activates:
Inhibits digestive activity
stimulates glucose release by the liver
Parasympathetic
Sympathetic
Double layer of peritoneum membrane that covers liver and stomach.
Lesser Omentum
Greater Omentum
Parietal Peritoneum
Double layer of peritoneum membrane that covers other abdominal organs and connects to back of cavity wall.
Lesser Omentum
Greater Omentum
Parietal Peritoneum
Double layer of peritoneum membrane that covers other abdominal organs and connects to back of cavity wall.
Lesser Omentum
Greater Omentum
Parietal Peritoneum
Covers entire abdominal and pelvic cavities (i.e., peritoneal cavity).
Lesser Omentum
Greater Omentum
Parietal Peritoneum
decrease gut activity
Sympathetic
Parasympathetic
increase gut activity
Sympathetic
Parasympathetic
the enteric nervous system can independently regulate gastrointestinal motility and secretion.
true
false
Cells from gut release ______ which stimulates submucosal IPANs.
5-HT
Ach
CGRP
ENS
IPANs release of ____________ and CGRP then activates the ENS responsible for peristaltic and secretory activity.
5-HT (serotonin)
Ach (acetylcholine)
CGRP (calcitonin gene related peptide)
ENS (enteric nervous system)
IPANS (intrinsic primary afferent neurons)
produced by pancreas cells
insulin
secretin
choleystokinin (CKK)
somatostatin
gastrin
Produced by enteroendocrine cells in small intestine
insulin
secretin
choleystokinin (CKK)
somatostatin
gastrin
Released by enteroendocrine cells in stomach
insulin
secretin
choleystokinin (CKK)
somatostatin
gastrin
Food that has been processed in the stomach. It is thick like heavy cream.
chyme
bile
Tube that runs from esophagus to large intestine. Contains various of tissues, muscle, and vessels.
Alimentary canal
Digestion
Peristalsis
Gastric glands cells
Mechanical and/or chemical breakdown of food.
Alimentary canal
Digestion
Peristalsis
Gastric glands cells
Involuntary wave-like constriction and relaxation of the muscles that propel food down alimentary canal.
Alimentary canal
Digestion
Peristalsis
Gastric glands cells
Include epithelial, mucous neck, chief, parietal, and enteroendocrine cells.
Alimentary canal
Digestion
Peristalsis
Gastric glands cells
Exist in 3 layers. Circular, longitudinal, and oblique (oblique found only in stomach).
GI tract muscles
GI sphincters
GI control
Muscular rings that can open or close to separate GI regions. Include upper esophageal, cardioesophageal sphincter, pyloric sphincter, and anal sphincter (external and external).
GI tract muscles
GI sphincters
GI control
GI and accessory organ activities are controlled by autonomic neuronal and hormonal signals.
GI tract muscles
GI sphincters
GI control
Primarily involved in nutrient absorption. Divided into duodenum, jejunum, and ileum.
Small intestine
Large intestine
Accessory Organs
Peritoneal membranes
Primarily involved in water absorption. Divided into cecum, appendix, colon, rectum, and anal canal.
Small intestine
Large intestine
Accessory Organs
Peritoneal membranes
Secrete various compounds that aid in digestion (e.g. bile, insulin). Includes liver, gallbladder, and pancreas.
Small intestine
Large intestine
Accessory Organs
Peritoneal membranes
Several layers that cover and hold GI system in place.
Small intestine
Large intestine
Accessory Organs
Peritoneal membranes
