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WorksheetsBacterial Infections of HL System Oct 25
Total questions: 15
Worksheet time: 8mins
Which of the following is the most common causative species of Brucellosis worldwide, known for its high virulence in humans?
Brucella melitensis
Brucella abortus
Brucella canis
Brucella suis
What is the characteristic Gram stain morphology and property of Brucella species?
Gram-negative diplococci, motile
Gram-positive rods, spore-forming
Gram-positive cocci, non-motile
Gram-negative coccobacilli, non-motile
A farmer presents with fever, night sweats, and joint pain. He frequently consumes raw goat milk. What is the most likely mode of transmission for his suspected Brucellosis?
Inhalation of aerosolized bacteria
Vector-borne transmission via ticks
Direct contact with an infected animal's wound
Ingestion of contaminated dairy products
Which organ system is most commonly affected in focal or chronic Brucellosis?
Central nervous system
Gastrointestinal system
Osteoarticular system
Cardiovascular system
The prozone phenomenon, which can cause a false-negative result in the Serum Agglutination Test (SAT) for Brucellosis, is due to:
Cross-reactivity with other bacteria
Antigen excess
Antibody deficiency
Antibody excess blocking agglutination
The World Health Organization (WHO) recommended first-line treatment regimen for uncomplicated adult Brucellosis is:
Amoxicillin plus clavulanate
Ciprofloxacin
Tetracycline
Doxycycline plus rifampicin
In the pathogenesis of Brucellosis, the bacterium primarily survives and replicates within which host cells?
Macrophages
Neutrophils
B-lymphocytes
Erythrocytes
A common complication of Brucellosis in males, particularly with B. melitensis infection, is:
Epididymo-orchitis
Pneumonia
Meningitis
Endocarditis
What is the primary reservoir for Leptospira species?
Dogs
Pigs
Rodents
Cattle
What is the most common route of transmission of leptospirosis to humans?
Contact with contaminated water or soil
Vector-borne via mosquitoes
Inhalation of droplets
Consumption of contaminated food
Which clinical presentation is characteristic of severe leptospirosis (Weil’s disease)?
Cough, hemoptysis, chest pain
Jaundice, renal failure, hemorrhage
Neuropathy, muscle weakness, paralysis
Skin rash, arthritis, conjunctivitis
Which organ system is most commonly affected in leptospirosis?
Musculoskeletal system
Respiratory system
Nervous system
Renal system
Which diagnostic test is considered the gold standard for leptospirosis?
Microscopic Agglutination Test (MAT)
PCR
Rapid diagnostic test
ELISA
Which antibiotic is commonly used for treating leptospirosis?
Amoxicillin
Doxycycline
Ciprofloxacin
Azithromycin
Which occupational group is at highest risk of leptospirosis?
Office employees
Teachers
Healthcare workers
Farmers and sewer workers
