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Replication, Transcription, and Translation— Biology I (Grade 7)

Total questions: 48

Worksheet time: 24mins

Name
Class
Date
1.

A group of K POP demon hunters—Niamah, Nia, and N'Yah—are gearing up for their next big mission! To heal quickly after epic battles, they need to know how their cells copy DNA. What steps should they write in their training manual about DNA replication?

a)

DNA is cut into pieces and mixed with proteins to form new chromosomes

b)

DNA unwinds; complementary nucleotides are added by DNA polymerase; two identical DNA molecules form

c)

RNA copies DNA directly into proteins in the ribosome

d)

The cell divides first, then DNA is made afterward

2.

Rashed, Pyrce, and Reese are on a mission as K POP demon hunters in their science lab! They're investigating how DNA replicates and stumble upon a mysterious enzyme that acts like a zipper, unzipping the DNA strands. Which enzyme is responsible for this unzipping action?

a)

DNA polymerase

b)

Helicase

c)

Ligase

d)

Ribosome

3.

During a science lab, Eleven, Mike, & Dustin—the Stranger Things crew—along with Stella & Taha from Ms. Solomon's class are building a model of DNA replication. As they separate the DNA strands, they realize something mysterious needs to swoop in and bring the missing parts to fill in the gaps. Which enzyme acts as the hero, bringing in the missing pieces during DNA replication?

a)

RNA polymerase

b)

Helicase

c)

DNA polymerase

d)

Primase

4.

Will, Eleven, and Yari are working together on a science project in Hawkins Lab about DNA replication. They discover that DNA replication is called “semi-conservative.” Can you help them figure out what “semi-conservative” means?

a)

Each new DNA molecule has two completely new strands

b)

Each new DNA molecule keeps one original strand and adds one newly made strand

c)

DNA is partly destroyed during replication

d)

Half of the chromosomes are copied each time

5.

Sam, Serenity, and Noel are on a science adventure as K POP demon hunters! They're trying to uncover the secret location where DNA replication happens inside a cell. Can you help them figure out where this important process takes place?

a)

Nucleus

b)

Cytoplasm

c)

Ribosome

d)

Cell membrane

6.

During a science class in Hawkins Middle School, Eleven, Rylann, and Rosalind are having a friendly debate about where transcription takes place in a cell. Can you help them settle the discussion by choosing the correct location for transcription?

a)

Nucleus

b)

Ribosome

c)

Golgi apparatus

d)

Cell membrane

7.

During their secret mission, Shanda Rose, Spencer, and Michael are helping the K POP demon hunters crack coded messages! In the process of transcription, what is made from what?

a)

mRNA is made from DNA

b)

DNA is made from mRNA

c)

tRNA is made from proteins

d)

rRNA is made from lipids

8.

Marc Jr., Bella Maria, and Bella are joining JISOO and MINHO on a K-POP demon hunting adventure! Before they can unlock the magical scroll, they must solve a genetics puzzle together. Help them fill in the chart: What is the difference in number of strands for DNA and RNA?

a)

DNA has two strands; RNA has one strand

b)

DNA has one strand; RNA has two strands

c)

Both DNA and RNA have two strands

d)

Both DNA and RNA have one strand

9.

Luke, Eleven, and Marcus are on a science quest in Hawkins! They're racing to fill in a chart that compares DNA and RNA to help solve a mystery in the Upside Down. Help them crack the code: What sugar is found in the backbone of DNA, and what sugar is found in RNA?

a)

DNA: ribose; RNA: deoxyribose

b)

DNA: deoxyribose; RNA: ribose

c)

DNA and RNA both use glucose

d)

DNA and RNA both use sucrose

10.

Kenna, Faith, and Calli have teamed up with Hopper and Joyce for a science adventure in Hawkins! To unlock the next clue hidden by the Upside Down, they need to fill in a chart showing the differences between DNA and RNA. Which bases should our Stranger Things squad list as found in DNA versus RNA?

a)

DNA: A, U, C, G; RNA: A, T, C, G

b)

DNA: A, T, C, G; RNA: A, U, C, G

c)

DNA: A, T, C, U; RNA: A, T, C, G

d)

DNA and RNA use the same bases

11.

During their epic science adventure, Lucas, Lucy, and Lila are on a quest to help the K POP demon hunters compare DNA and RNA! They need to fill in the chart to reveal the secrets of these molecules. When it comes to leaving the nucleus, which one has the special pass—DNA or RNA?

a)

DNA can leave; RNA cannot

b)

RNA can leave; DNA cannot

c)

Neither DNA nor RNA can leave

d)

Both DNA and RNA can leave

12.

Drew, Kendall, and Liam are on a secret mission in Hawkins to stop a sneaky science Demigorgon-y creature from the Upside Down! To crack the creature’s code, they need to fill in the chart showing the roles of different RNA agents. What super-important job does mRNA have?

a)

Forms the ribosome and catalyzes peptide bonds

b)

Carries amino acids to the ribosome

c)

Carries the genetic code from DNA to the ribosome

d)

Cuts introns out of DNA

13.

Abigail, Koen, and Briggs are legendary K-POP demon hunters on a wild mission! They're filling out a chart to figure out which team member does what during their epic demon hunt. If one of them acts like tRNA, what is their special job?

a)

Carries special weapons to the battle site

b)

Carries the mission instructions from headquarters to the team

c)

Replicates the team's strategy

d)

Stores secret information back at headquarters

14.

NYAH, ROS, SERENITY, and their squadmates Daniel and Charlotte are K POP demon hunters on a top-secret mission! They're working together to fill in a chart about the roles of different team members in their squad. When it comes to rRNA, what special job does it have in their epic quest?

a)

Forms the main base (like the ribosome) and helps coordinate the creation of new battle strategies (like catalyzing peptide bond formation)

b)

Delivers special weapons to the base (like carrying amino acids to the ribosome)

c)

Brings secret mission codes from headquarters to the base (like carrying the genetic code from DNA to the ribosome)

d)

Repairs damaged equipment after battles (like repairing DNA breaks)

15.

In the mysterious Hawkins lab, DUSTIN, ELEVEN, and LUCAS are on a mission to uncover the secrets of RNA! Diagram A shows what DUSTIN discovered: a ribosome with strange internal squiggles. Diagram B reveals what ELEVEN found: a cloverleaf-shaped molecule. Diagram C displays what LUCAS observed: a long single-stranded chain of nucleotides. Can you help them out by labeling each diagram as mRNA, tRNA, or rRNA?

a)

mRNA

b)

tRNA

c)

rRNA

16.

Mike, Eleven, and Dustin have teamed up with Hopper and Joyce on a mysterious mission in Hawkins! They're decoding a secret message from the Upside Down by analyzing diagrams of strange RNA molecules. Diagram B reveals a cloverleaf-shaped molecule. Can you help the team label each diagram as mRNA, tRNA, or rRNA?

a)

mRNA

b)

tRNA

c)

rRNA

17.

During a biology lab, Eleven, Mike, and Dustin from the Stranger Things group are on a quest to identify mysterious RNA diagrams! Diagram C reveals a long single-stranded chain of nucleotides. Can you help them label each diagram as mRNA, tRNA, or rRNA? What type of RNA is shown in Diagram C?

a)

mRNA

b)

tRNA

c)

rRNA

18.

Mike, Eleven, and Dustin are on a science quest in Hawkins, trying to discover where cells build their proteins! Can you help them answer: Where in the cell does translation happen?

a)

At ribosomes in the cytoplasm

b)

In the nucleus

c)

In the mitochondria matrix

d)

At the cell membrane

19.

During a biology lab, Landon, Lillian, and Lilly—who moonlight as K POP demon hunters—are using their notes to crack the mystery of translation (mRNA to Protein). In this epic process, what is made from what?

a)

Protein is made from amino acids

b)

mRNA is made from proteins

c)

DNA is made from amino acids

d)

Amino acids are made from DNA

20.

During a high-stakes mission briefing, Keyliana, J-Lux, and Jack-Jack—the K POP demon hunters—are racing to decode secret messages. Suddenly, they stumble upon a clue: 3 bases of mRNA are called a(n)... What do they discover?

a)

codon

b)

anticodon

c)

exon

d)

centromere

21.

On a top-secret K POP mission, Chase, Jeankarlys, and Maria are racing to decode how cells make proteins! They stumble upon a clue: 3 bases of tRNA are called a(n)... What do you think it is?

a)

anticodon

b)

codon

c)

intron

d)

polymerase

22.

During a science experiment in Hawkins Middle School, Ms. Scott, Alex, and Jayvon watched as mRNA helped build a protein, just like in their favorite biology lesson. They celebrated when a long chain of amino acids started to form. What is this chain called?

a)

polypeptide

b)

chromosome

c)

nucleotide

d)

centrosome

23.

Bennet, Brayan, and Dominic are on a K-POP-inspired adventure as secret codebreakers! They discover a magical diagram where the first arrow shows a DNA sequence being transformed into an mRNA sequence, and the second arrow reveals the mRNA sequence being decoded into amino acids to build a powerful protein for their next quest. Using your knowledge of protein synthesis, what are the names of these two amazing processes?

a)

Transcription

b)

Translation

c)

Replication

d)

Point mutation

24.

Reese, Christian, and Drew are K POP demon hunters training for their next big battle! To power up, they need to know how their cells make proteins. Using their Protein Synthesis Notes and Review Sheet, they debate: What is the first step in protein synthesis, and what comes next?

a)

Transcription; Translation

b)

Translation; Transcription

c)

Replication; Translation

d)

Replication; Transcription

25.

Evelyn, Briggs, and Kenna are K POP demon hunters on a mission to unlock the secret behind their superpowers! While analyzing mysterious DNA samples, they spot a sneaky change in just one nucleotide base. What type of mutation did our heroes discover?

a)

A change in a single nucleotide base

b)

Insertion of several bases that shifts the reading frame

c)

Loss of large parts of a chromosome

d)

Exchange of entire genes between chromosomes

26.

In Hawkins Middle School, Dustin and Lucas are discussing strange happenings in the Upside Down. Dustin asks Lucas: "If the Demogorgon messed with someone's DNA, causing a frame shift mutation, what exactly does that mean and why is it important in genetics?" What should Lucas say to impress Dustin?

a)

Insertion or deletion of a base that changes the reading frame

b)

A change in one base with no frame change

c)

A mutation occurring only in mitochondria

d)

A temporary change that is immediately repaired

27.

Mike, Eleven, and Dustin are on a science adventure in Hawkins, exploring how mutations travel from parents to children! Which of the following explains how a mutation can be inherited?

a)

It must occur in sex cells (gametes) and be passed on during reproduction

b)

It occurs in skin cells and spreads to the offspring

c)

It is only possible through environmental exposure after birth

d)

Only mutations in the brain are inherited

28.

During a high-energy K POP demon hunter training session, Landon, Drew, and Koen are swapping stories about wild mutations! Using your Mutations Notes in the DNA Notes Packet, what are some causes of mutations that they might mention? Select all that apply.

a)

Errors during DNA replication

b)

Exposure to UV radiation or certain chemicals

c)

Certain viruses

d)

Eating a balanced diet

29.

On their latest adventure, K POP demon hunters Ethan, Aiden, and Eli crack an encrypted message. They notice the secret code changes from AAATACGCG to AATACGCG. What type of mutation did the team discover?

a)

Deletion (frameshift)

b)

Insertion (frameshift)

c)

Substitution (point mutation)

d)

Duplication of a gene

30.

Evelyn, Hadley, and Hadyen are part of a K POP demon hunter squad, and they're on a mission to boost their superpowers by studying DNA mutations! During their research, they notice a DNA segment changes from AAATACGCG to AAAATACGCG. What type of mutation did the squad discover?

a)

Insertion (frameshift)

b)

Deletion (frameshift)

c)

Substitution (point mutation)

d)

Inversion

31.

During a science experiment in Hawkins Lab, Dustin and Eleven were investigating DNA changes. They discovered that a DNA segment switched from AAATACGCG to AAATACGCT. Can you help them figure out what type of mutation occurred?

a)

Substitution (point mutation)

b)

Insertion

c)

Deletion

d)

Duplication

32.

Three K-POP demon hunters—James, Hannah, and Ethan—are teaming up in their training room to crack a magical scroll’s secret code! The scroll is being read by a mystical device, while enchanted messengers rush in with special stones to help build a powerful protective charm. What process is happening in this epic scene? (circle one)

a)

DNA replication

b)

Transcription

c)

Translation

33.

On a top-secret K POP mission, demon hunters MINJI and JISOO team up with Hannah, Sophia, and Charlotte to crack the magical translation diagram! As they race to unlock their powers, they stumble upon a mysterious structure labeled A. Can you help them figure out what it is?

a)

Ribosome

b)

mRNA

c)

tRNA

d)

Polypeptide chain

34.

Abigail, Ava, and Hannah are on a top-secret K POP demon hunter mission! They're decoding a mysterious translation diagram to uncover magical clues. In the diagram, what is the structure labeled B that the team needs to identify?

a)

mRNA

b)

Ribosome

c)

tRNA

d)

Amino acid

35.

Mike, Eleven, and Dustin are investigating a mysterious diagram in the Hawkins lab, trying to decode how the Upside Down communicates with our world. They spot a structure labeled C and start guessing what it could be! Can you help them out? What is the structure labeled C?

a)

tRNA

b)

Amino acid

c)

Codon

d)

Ribosome

36.

During a science adventure in Hawkins Lab, Eleven, Mike, and Dustin are trying to solve the mystery of a translation diagram to help decode a secret message from the Upside Down! In the diagram, what is the structure labeled D?

a)

Amino acid

b)

Anticodon

c)

Codon

d)

Polypeptide chain

37.

Mike, Eleven, and Dustin are in the Hawkins lab, trying to decode a mysterious translation diagram they found while investigating the Upside Down. They spot the feature labeled E and wonder: What is this strange part?

a)

Anticodon on tRNA

b)

Codon on mRNA

c)

Ribosome

d)

DNA

38.

In Hawkins Middle School’s science lab, Dustin, Eleven, and Lucas are investigating a mysterious translation diagram that looks like something straight out of the Upside Down. They notice a three-base codon on the mRNA strand and are trying to figure out what the feature labeled F represents in the diagram. Can you help them solve this biology puzzle?

a)

Codon on mRNA

b)

Anticodon on tRNA

c)

Amino acid

d)

Ribosome

39.

During a special K POP demon hunter training session, Luna, Maya, and Elijah are teaming up to crack the code of a translation diagram! The diagram shows a growing polypeptide chain emerging from the ribosome. The squad is stumped by the structure labeled G. Can you help them out? What is the structure labeled G?

a)

Polypeptide chain

b)

Ribosome

c)

mRNA

d)

tRNA

40.

Abigail, James, and Jackson are on a quest to become legendary K POP demon hunters, but first, they must solve a biology mystery! In class, they spot a diagram showing a DNA double helix with a single-stranded RNA molecule being created from one DNA strand. What epic process are they witnessing in the lower diagram? (circle one)

a)

DNA replication

b)

Transcription

c)

Translation

41.

During a top-secret monster hunt, student detectives Kai, Evelyn, and Ethan are teaming up with K POP demon hunters MINJI and HANI! They're staring at a transcription diagram to crack the genetic code of a mysterious creature. Can you help them figure out: Which molecule in the diagram is the RNA?

a)

The single-stranded green molecule produced alongside the DNA

b)

The double-stranded gray helix

c)

Both strands of the helix

d)

The entire diagram shows only DNA

42.

Emma and Mason, our K POP demon hunters, are on a top-secret mission! They're decoding a mysterious message using a transcription diagram. Can you help them figure out which structure in the diagram is the DNA?

a)

The double-stranded gray helix

b)

The single-stranded green molecule

c)

Only the template strand shown

d)

A tRNA molecule

43.

Charlotte, Aria, and Sophia are on a science adventure! They’re examining the diagram to the right, which shows a DNA double helix being copied. What amazing process are they witnessing? (circle one)

a)

DNA replication

b)

Transcription

c)

Translation

44.

Mike, Eleven, and Dustin are working on a science project in Hawkins! They want to know how many codons are needed to bring in 5 amino acids to build a super cool protein for their experiment. Can you help them figure out how many codons they need?

a)

4

b)

5

c)

6

d)

10

45.

During a lively training session, Henry, Scarlett, and Sophia—the K POP demon hunters—are on a quest to discover how proteins are made in cells. They stumble upon a mysterious clue: the start codon! Can you help them figure out what the start codon is?

a)

AUG

b)

UGA

c)

UAA

d)

UAG

46.

In Hawkins High’s biology class, Mike, Eleven, and Dustin are discussing how proteins are made. They’re wondering: when building a protein, which amino acid does the start codon signal for?

a)

Methionine

b)

Lysine

c)

Proline

d)

Glycine

47.

During a high-energy biology quiz, K POP demon hunters Sophia, Elijah, and Lily are on a mission to crack the genetic code! They're trying to remember the three stop codons that signal the end of protein synthesis. Can you help them out? What are the three stop codons?

a)

UAA

b)

UAG

c)

UGA

d)

AUG

48.

At a K POP demon hunters' strategy meeting, William, Mason, and Charlotte are discussing their next mission. NYAH asks, "When the demon hunters receive a stop signal during their mission, what does it instruct them to do?"

a)

No action; it signals the end of the mission

b)

Start with Methionine

c)

Proceed with Tryptophan

d)

Continue with Proline