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Necrosis and Its Types Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Necrosis is characterized by:

a)

No inflammation

b)

Apoptosis features

c)

Loss of membrane integrity

d)

Cell shrinkage

2.

Coagulative necrosis is typically seen in:

a)

Brain infarct

b)

TB

c)

Ischemic injury to kidney

d)

Lipid-rich tissues

3.

Liquefactive necrosis is classical in:

a)

Liver infarction

b)

Brain infarction

c)

Spleen infarction

d)

Heart infarction

4.

Caseous necrosis is seen in:

a)

Ischemia

b)

Fungal infection

c)

TB

d)

Pancreatitis

5.

Fat necrosis in pancreatitis is due to:

a)

Protein denaturation

b)

Lipase action

c)

ROS

d)

Calcium depletion

6.

Fibrinoid necrosis occurs in:

a)

Brain infarct

b)

TB

c)

Vasculitis

d)

Pneumonia

7.

Dry gangrene is:

a)

Infection plus ischemia

b)

Pure ischemia

c)

Only infection

d)

Immunologic

8.

Wet gangrene includes:

a)

Only ischemia

b)

Bacterial infection only

c)

Ischemia plus infection

d)

Viral infection

9.

Gas gangrene is caused by:

a)

Staph aureus

b)

E. coli

c)

Clostridium perfringens

d)

TB

10.

Caseous appearance is:

a)

Soft and liquid

b)

Firm and dry

c)

Cheese-like

d)

Gelatinous

11.

First biochemical change in reversible injury:

a)

Nuclear pyknosis

b)

ATP depletion

c)

Membrane rupture

d)

Karyolysis

12.

Most important consequence of ATP depletion:

a)

Cell shrinkage

b)

Na/K pump failure

c)

DNA damage

d)

Mitochondrial fission

13.

Mitochondrial permeability transition leads to:

a)

ATP increase

b)

More protein synthesis

c)

ATP failure

d)

Less ROS

14.

Increased cytosolic Ca2+ causes:

a)

Inhibits enzymes

b)

Activates destructive enzymes

c)

Prevents ROS

d)

Stabilizes membranes

15.

Free radicals primarily damage:

a)

Ribosomes

b)

Mitochondria only

c)

All cellular components

d)

Lysosomes only

16.

Lipid peroxidation is caused by:

a)

Calcium

b)

ATP depletion

c)

ROS

d)

Proteases

17.

Membrane damage results in:

a)

Reduced permeability

b)

Cell swelling and enzyme leakage

c)

Increased ATP

d)

Cell shrinkage

18.

Early reversible injury feature:

a)

Nuclear fragmentation

b)

Swelling of ER

c)

Membrane rupture

d)

Karyorrhexis

19.

Lysosomal rupture causes:

a)

Cell protection

b)

Autodigestion

c)

ATP generation

d)

Cell repair

20.

Cytochrome c leakage leads to:

a)

Necrosis only

b)

Apoptosis

c)

Mitosis

d)

Inflammation