WorksheetsInflammation and Wound Healing Quiz
Total questions: 20
Worksheet time: 10mins
Systemic effects of inflammation are collectively called
Local response
Acute phase response
Delayed hypersensitivity
Granulomatous reaction
Major cytokine responsible for fever in inflammation is
IL-10
IL-4
IL-1
TGF-β
Acute phase proteins are synthesized mainly by
Spleen
Lymph nodes
Liver
Bone marrow
C-reactive protein is increased in
Chronic inflammation only
Acute inflammation only
Both acute and chronic inflammation
Allergic reactions
Leukocytosis in acute inflammation is due to
Increased RBC production
Release of neutrophils from bone marrow
Decreased neutrophil death
Increased lymphocyte apoptosis
Healing by first intention is also called
Secondary union
Delayed union
Primary union
Tertiary union
Healing by first intention occurs in
Infected wounds
Large tissue loss
Clean surgical incision
Burn wounds
Most important cell in wound healing is
Neutrophil
Macrophage
Eosinophil
Mast cell
Initial event in wound healing is
Angiogenesis
Collagen deposition
Hemostasis and inflammation
Epithelialization
Epithelialization in first intention healing begins within
24–48 hours
3–5 days
7–10 days
2 weeks
Collagen deposited early in wound healing is mainly
Type I collagen
Type II collagen
Type III collagen
Type IV collagen
Healing by second intention is characterized by
Minimal scar
No granulation tissue
Large granulation tissue and wound contraction
Absence of inflammation
Main mechanism of wound contraction is due to
Neutrophils
Fibroblasts
Myofibroblasts
Macrophages
Compared to first intention, second intention healing has
Smaller scar
Faster healing
Larger scar and more fibrosis
Less angiogenesis
Granulation tissue consists of
Only fibroblasts
New capillaries and fibroblasts
Only inflammatory cells
Only collagen fibers
Factor that delays wound healing
Systemic steroids
Good nutrition
Young age
Good blood supply
Local factor affecting wound healing includes
Age
Anemia
Infection
Diabetes mellitus
Vitamin essential for collagen synthesis is
Vitamin A
Vitamin C
Vitamin D
Vitamin K
Diabetes delays wound healing mainly due to
Increased collagen synthesis
Poor angiogenesis
Reduced inflammation
Enhanced epithelialization
Systemic effect of severe inflammation leading to hypotension is called
Shock
SIRS
Sepsis
Anaphylaxis
