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WorksheetsDermatrophic Viral Disease
Total questions: 43
Worksheet time: 26mins
large family of viruses
means "to creep"
about 100 species known including animal
rubella
measles
herpes
how many human herpes viruses are known
what are the known human herpes virus
Herpes Zoster Virus, Human Papillomavirus 6, 7, 8
Herpes Simplex Virus 3, Herpes Simplex Virus 4, Cytomegalovirus, Human Herpesvirus 6, 7,8.
Herpes Simplex Virus 1, 2, Varicella-Zoster Virus, Epstein-Barr Virus, Cytomegalovirus, Human Herpesvirus 6, 7,8.
what are the common features of the Herpes viruses?
non-enveloped with spikes
icosahedral capsid
enveloped with spikes
dsDNA,
ssDNA
common features of Herpes Viruses in terms of manifestations?
Occasional Recurrence
Latency Periods (hiding)
Incurable
Single outbreak
Chronic
Herpes Simplex Virus has 2 strains which are HSV-1 and HSV2 what are the differences and similarity?
HSV-1 is oral
HSV-2 is genitally
approximately 50% identical
approximately 90% identical
both are symptomatic
HSV-1 and HSV-2 are both the following
infect mucosa
most are asymptomatic
"viral shedding" 5% of the time during latency
"viral shedding" 5% of the time during incubation period
infect URT
characteristic episodes of HSV
formation of painful vesicles (blisters)
tingling or itching sensation
ulceration of vesicles
pus exudation
where do HSV-1 prefers to establish
near ear
near base of spine
sacral ganglion
trigeminal ganglia
where do HSV-2 prefers to establish
near ear
near base of spine
sacral ganglion
trigeminal ganglia
which HSV is more common and what's the statistics?
HSV-1
HSV-2
1 in 5 people
50-80%
factors affecting HSV outbreak?
Stress & Immune Suppression
Site of Infection
Duration of infection
Genetics
Age
HSV-1 infection in childhood makes HSV-2 infection during adolescence less likely
TRUE
FALSE
what are the complications of HSV-1?
Herpes Whiltow / finger infection
Ocular Herpes / pink eye
Herpes encephalitis / brain tissue
Neonetal Herpes / mother to baby
what are the complications of HSV-2?
Herpes Whiltow / finger infection
Ocular Herpes / pink eye
Herpes encephalitis / brain tissue
Neonetal Herpes / mother to baby
Antiviral Treatment for Herpes
Acyclovir, Vidarabine
Lopinavir, Ritonavir
Amantadine, Pimantadine
HSV-2 vaccines targets ______ in phase I to III clinical trials
the viral DNA envelope proteins and spikes
Herpes virus responsible for chicken pox and shingles
transmitted via resp. secretions
Herpes virus responsible for chicken pox and shingles
transmitted via resp. secretions
how long is the incubation period of Varicella-zoster virus (VZV)?
14 to 21 days
Varicella-zoster virus (VZV) is life-threatening
True
False
occurs in 15% of infected population
not new infection
known as shingles
Herpes Zoster is characterized as
a painful vesicles following sensitization of skin
about 20% of Herpes Zoster infection can lead to ______
a pain that can persist for months to years
post herpetic neuralgia
post herpetic pain syndrome
which are true about Varicella vaccine or chicken vaccine
live attenuated given 1-2 years of age
may decreased shingles incidence
increases shingles incidence
boosters at 18 years old
name of the new shingles vaccine
free in Ontario for those 65-70 years old
highly contagious disease transmitted by respiratory droplets
1-2 weeks incubation period
Measles
Mumps
Rubella
viral characteristics of Measles (Rubeola)?
ssRNA
dsDNA
enveloped
non-enveloped
viral characteristics of Mumps?
ssRNA
dsDNA
enveloped
non-enveloped
Aside from Fever, sore throat, hacking cough,
Measles manifestation include
Koplik's Spots
Conjunctivitis
Kypochia Lesions
Skin Rash
skin rash is one of the clinical manifestations of measles. Which are true about them?
appears 1-2 days after oral lesions
begins in head to trunk
red patches turn brown
beings posterior to anterior trunk
brown patches to red
name means "little red" or mild-rash
2-3 weeks incubation period
Measles
Mumps
Rubella
aside from slight fever, mild cold symptoms
manifestations of RUBELLA include
enlarged lymph nodes
painful joints in adults
brown patches
faint rash over face, chest, abdomen
joint pain in Rubella is caused by
Immune response to antigen-antibody complexes.
what is the major concern for Rubella?
Rubella can lead to
Congenital Rubella Syndrome
Miscarriages / Still births
Fetal Malformations
Meningitis
acute viral disease attacking parotid glands (parotitis)
transmission via resp. droplets contact, fomites
2-3 weeks incubation period
Measles
Mumps
Rubella
pathogenesis of mumps involving
ulceration
swelling
blockage
inflammation
mumps infection doesn't always parotid gland
True
False
MUMPS may develop into
multiple sclerosis
nueroglemia
meningitis
amongst MMR viruses, which is the smallest?
amongst MMR viruses, which is the most stable?
amongst MMR viruses, which is not stable?
