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WorksheetsViscerotropic Viruses
Total questions: 44
Worksheet time: 25mins
inflammation of the liver
80-90% viral causes
most infectious
15-50 days incubation
fecal-route
eating drinking
sexual transmission
Hepatitis A
Hepatitis B
Hepatitis C
symptoms of Hepatitis A includes
dark coloured urine, clay coloured stools
jaundice in 10% of patients
flu-like symptoms to life threatening liver failure
jaundice to 30% of patients
cirrchosis, cancer, profound fatigue, jaundice
what are true about Hepatitis A epidemiology?
Sporadic
Low incidence
Acquired in developing countries
More common in adolescents
Self-limiting disease
How to prevent Hepatitis A?
most prevalent reported strain of Hepatitis virus
more difficult to acquire
has mutants
Hepatitis B viral structure
dsDNA
ssDNA
enveloped
non enveloped
Hepatitis A viral structure
ssRNA
dsDNA
enveloped
non enveloped
Hepatitis B has 3 forms such as Full Virion _____ & ___________
Coccus
Spheres and Tubes
Capsomere without genome
Icosahedral
what is the incubation period for Hep B?
3-6 months
2 months
1-4 months
HEP B can be transmitted through the following except
Needles
Sexual Transmission
Birth
Secretions
Fomites
what does Chronic Hepatitis B means?
carrier is asymptomatic
never develops antibodies
no liver injury
rapid destruction of liver but rare
severe hepatitis state for 6-12 months without recovery
what does severe acute Hepatitis B means?
carrier is asymptomatic
never develops antibodies
no liver injury
rapid destruction of liver but rare
severe hepatitis state for 6-12 months without recovery
what does CHRONIC ACTIVE Hepatitis B means?
carrier is asymptomatic
never develops antibodies
no liver injury
rapid destruction of liver but rare
severe hepatitis state for 6-12 months without recovery
% of complete recovery in HEP B with immunity?
80-90%
amongst 3 Hep B vaccines, which is the FIRST developed
vaccine made from plasma of people with HEP B
protein vaccine
HBV genetic material
what is the treatment for chronic hepatitis?
aim to decrease viral level & improve appearance of liver
interferon therapy
liver transplant
corticosteroids for liver inflammation
Hepatitis C viral structure
ssRNA
dsDNA
enveloped
non enveloped
EBOLA structure is
ssRNA
dsDNA
enveloped
non enveloped
filamentous
HIV structure is
ssRNA
dsDNA
enveloped
non enveloped
filamentous
has proteins which prevents host cell death
has never been cultured
infection starts 15 days to 5 months
Hepatitis B
Hepatitis A
Hepatitis C
Hepatitis C is largely transmitted through
Blood Transfusions
Needle Sharing, Tattooing, Body piercing
Tooth brush, razor
Fomites
Respiratory Droplets
Hepatitis C disease can be accelerated by
alcohol consumption
what is the combination drug that can can cure HEP C?
HARVONI is a combination drug include nucleotide analogue and assembly inhibitor for which Hepatitis?
how to prevent Hepatitis C?
screen blood supply
avoid high risk behavior
wash your hands
avoid travelling
There is no vaccination available for Hepatitis C
True
False
why is Ebola a deadly virus?
Ebola is unstoppable and can't be contained.
Ebola is deadly because it affects all cells in the body.
Ebola has a high transmission rate and untreatable symptoms.
Ebola is under which viral family?
how many proteins is Ebola capable of encoding?
incubation period of Ebola
what is considered a serious symptom of Ebola?
Hemorrhagic Fever
Ebola can progress to
what do you call the approved Vaccine in Canada for Ebola?
Ebola vaccine: ERVEBO, is only given to those
which virus cause non-healing wounds and promotion of other infections
possible symptoms of HIV?
opportunistic infections
persistent fever
extensive weight loss
neurological disorders
joint stiffness
HIV lipid envelope contains GP41 and GP120 which are responsible for
GP41 for penetration
G120 for binding
GP41 for replication
G120 for blockage
HIV targets which cells
what happens when CD4 Helper T-cells are targeted by HIV?
CD4 Helper T-cells fail to activate antibody cascade
Body can't mount an immune response through macrophages, T cells, B cells
CD4 Helper T-cells can't release cytokines
AIDS/HIV can only be transmitted through
first 2-3 weeks
disappear in their own in 1-4 weeks
symptomatic
Primary HIV Infection
Latency Infection
AIDS
can last up to 2-15 years
silent struggle between HIV and CD4 cells
asymptomatic
Primary HIV Infection
Latency Infection
AIDS
CD4 count is < 200 cells
Primary HIV Infection
Latency Infection
AIDS
