WorksheetsUnit 3: DNA & Proteins EOC Review
Total questions: 230
Worksheet time: 38hrs 20mins
A portion of one strand of a DNA molecule has the sequence shown below. ACCTGAAGG Assuming there are no mutations in this portion of the DNA, what is the corresponding sequence on the complementary DNA strand?
ACCTGAAGG
GTTCAGGAA
TGGACTTCC
UGGACUUCC
Partial amino acid sequences for a particular protein in three animal species are shown below. Each letter in the sequence stands for an amino acid. For example, Q stands for glutamine, and L stands for leucine. Species Amino Acid Sequence Green junglefowl (bird) QHEPHERKRM Nile crocodile (reptile) SHDPAQQKRL Domestic chicken (bird) QHEPHKRKRM Which of the following statements best explains how these sequence data are evidence for evolution?
All species translate the amino acid sequences of their proteins in a similar way.
The species that are most closely related have the most similar amino acid sequences.
Individual organisms acquire changes in their amino acid sequences over their lifetimes.
The organisms that evolved at the same time in geologic history have identical amino acid sequences.
Based on the information in the table, which of the following changes is least likely to produce a phenotypic change in an organism?
GAU to GGU
GAU to GUU
GAU to GAA
GAU to GAC
An RNA sequence is shown below. AUGCCGAAAACGU Which of the following statements describes how the RNA sequence specifies the production of an amino acid chain?
Each individual RNA base codes for a single amino acid.
Each group of three RNA bases codes for a single amino acid.
Each group of three RNA bases codes for an enzyme that helps join amino acids together.
Each individual RNA base codes for the ribosome location where amino acids are assembled.
Which of the following describes the function of DNA?
encoding genetic information
storing energy in chemical bonds
speeding up biochemical reactions
destroying substances that enter the cell
Based on the data in the table, which two species are most closely related?
Species A and Species B
Species B and Species C
Species A and Species C
Species B and Species D
Which of the following are three forms of scientific evidence that could be used to study the relatedness of four animal species?
DNA sequencing, fossil records, and anatomical comparisons
Weather patterns, migration routes, and food preferences
Color patterns, vocalizations, and habitat types
Population size, geographic range, and reproductive rate
What is the likely effect of a mutation that causes the sequence CGC to become CGG?
A. The reading frame will be shifted.
B. The protein formed will be unchanged.
C. The protein will be translated incorrectly.
D. The translation process will stop prematurely.
A strand of DNA has these bases: AGC CAT GTA TAC. What is the complementary DNA strand?
ACG GAT CTA TAG
TCG GTA CAT ATG
TGC CTA GAT ATC
UCG CUA CAU AUG
A segment of DNA has this sequence: ATA GCA CAT GTA. What is the mRNA sequence transcribed from this segment?
TAT CGT GTA CAT
TAT GCT CTA GAT
UAU CGU GUA CAU
UAU GCU CUA CAU
Which amino acids are coded for by an mRNA segment that reads CAG GUG?
arginine and valine
isoleucine and arginine
glutamine and valine
valine and isoleucine
How does DNA code for proteins in a cell?
by creating a new double helix structure
by using its phosphate and sugar molecules
by adding more hydrogen bonds to its structure
by arranging certain nitrogen bases of the cell in a particular order
Which factor most affects the order of amino acids in a protein?
the DNA located in the nucleus of the cell
the cell in which the protein is located
the amount of ATP available for the cell’s use
the area in a cell where proteins are produced
Which nitrogen base makes RNA different from DNA?
guanine
uracil
adenine
Which base bonds with adenine in DNA?
cytosine
uracil
thymine
The first step in the process of DNA replication as shown in the diagram is:
Unwinding of the DNA double helix
Joining of Okazaki fragments
Formation of new hydrogen bonds
Proofreading of newly synthesized DNA
Which nucleotides pair together in the DNA molecule?
A pairs with T
C pairs with G
A pairs with C
T pairs with G
Fill in the blank: The result of DNA replication is _______.
two complete DNA molecules
one incomplete DNA molecule
three DNA molecules
two RNA molecules
During DNA replication, nucleotides are attached to the original strands to form new DNA molecules.
True
False
A partial DNA sequence for normal hemoglobin and a partial DNA sequence for sickle-cell anemia are shown below. G-G-A-C-T-T-C-T-T Normal hemoglobin G-G-A-C-A-T-C-T-T Sickle-cell anemia Based on the DNA sequences, sickle-cell anemia is caused by
a sex-linked trait.
a dominant nucleotide.
a mutation in the genetic code.
an incomplete separation of chromosomes.
Which of these provides the best evidence of a close evolutionary relationship between two species?
similar sequences of the nucleotides in the DNA molecules
similar processes of replicating DNA molecules during cell division
similar numbers of chromosomes formed by the DNA molecules
similar numbers of mutations that occur in DNA molecules over time
Portions of the DNA sequences from two different animal species are shown below. The DNA sequences of the two species are similar. Based on the similarity in the DNA sequences, which is most likely true?
The two species have the same diet.
The two species live in the same environment.
The two species have a close evolutionary relationship.
The two species are able to mate and produce fertile offspring.
The discovery of which of the following has most directly led to advances in the identification of suspects in criminal investigations and in the identification of genetic diseases?
antibiotics
cell structure
DNA structure
sterile procedures
Which of the following is the template for the production of RNA within a cell?
DNA
ATP
protein
carbohydrate
Which sequence of DNA bases would pair with the ones shown in the partial strand below?
ATG TGA CAG
TAC ACT GTC
GTA AGT GAC
CAT TCA CTG
What molecules do both DNA and RNA contain?
uracil
thymine
nucleotides
deoxyribose
The genetic material of an organism is composed of
lipids.
proteins.
deoxyribonucleic acids.
complex carbohydrates.
Which of the following best describes how DNA and RNA are similar?
They both contain the nitrogen bases thymine and adenine.
They both are formed in a double-helix structure.
They both are composed of five different nucleotides.
They both contain the nitrogen bases cytosine and guanine.
The diagram below shows Rosalind Franklin’s x-ray diffraction image of DNA. How did this evidence affect the work of Watson and Crick?
It was used to determine the physical structure of DNA.
It was used to identify the four bases that make up DNA.
It was used to develop the theory of independent assortment.
It was used to show that DNA was the molecule of inheritance.
Which information was most important to the development of genetic engineering techniques?
the observation of nondominant alleles
the discovery of lethal genes
the formulation of Punnett squares
the structure of a DNA molecule
A strand of mRNA containing the repeating sequence AAGAAGAAGAAG could code for which of the following amino acid sequences?
lys–arg–glu–lys
ser–ser–glu–glu
lys–arg–lys–arg
lys–lys–lys–lys
The above sequence of DNA is part of a gene. How many amino acids are coded for by this segment?
4
8
12
20
A scientist puts nucleotide chains of UUUUUU in a test tube under conditions allowing protein synthesis. Soon the test tube is full of polypeptide chains composed of only the amino acid phenylalanine. What does this experiment indicate?
The amino acid phenylalanine is composed of uracil.
UUU codes for the amino acid phenylalanine.
Protein synthesis malfunctions in test tubes.
Most proteins contain only one type of amino acid.
Which of the following base pair sequences could be produced in DNA replication?
5' AGTCUT 3' 3' TCUGTA 5'
5' AGTCAT 3' 3' TCAGTA 5'
5' AGTCAT 3' 3' CTGACG 5'
5' AGTCAT 3' 3' UCAGUA 5'
A base sequence is shown below. ACAGTGC How would the base sequence be coded on mRNA?
A. TGTCA CG
B. GUGACAU
C. UGUCACG
D. CACUGUA
Semi-conservative replication of DNA refers to the idea that
DNA molecules need to unwind before duplication begins.
each new DNA molecule contains two new single RNA strands.
the two strands of DNA molecules run in opposite directions.
each half of the original DNA molecule is joined with a new complementary DNA strand.
The diagram below shows the procedure scientists used to clone a frog from the nucleus of a skin cell. This procedure is evidence that ________.
the nuclei of the skin cells protect the frog
only skin cells can be used to clone a frog
the skin cells are the reproductive cells of the frog
the nuclei of skin cells contain all the DNA needed for a new frog
What is the relationship between the three structures in the diagram above?
DNA is produced by protein which is produced in the cell.
Protein is composed of DNA which is produced in the cell.
DNA controls the production of protein in the cell.
A cell is composed only of DNA and protein.
Which statement about DNA is correct?
A. A child's DNA will be unrelated to the mother's or father's DNA.
B. A child's DNA will show similarities to both the mother's and father's DNA.
C. A female child's DNA will exactly match the mother's DNA.
D. A male child's DNA will exactly match the father's DNA.
The table shows which mRNA codons code for various amino acids. Which amino acid sequence will be produced by translation of the mRNA sequence UAC UCU ACC?
A. Asn – Pro – Thr
B. Thr – Pro – Asn
C. Thr – Ser – Tyr
D. Tyr – Ser – Thr
Which statement about DNA is correct?
A child's DNA will be unrelated to the mother's or father's DNA.
A child's DNA will show similarities to both the mother's and father's DNA.
A female child's DNA will exactly match the mother's DNA.
A male child's DNA will exactly match the father's DNA.
DNA contains the code for constructing which molecules?
proteins
fats
starches
sugars
The diagram below shows the chromosomes from a cell after they were photographed under a microscope. Which of the following questions may best be answered by studying an organism's chromosomes?
What sex is the organism?
Is the organism endangered?
Where is the organism's ecosystem?
How does the organism obtain its food?
Which of the following best describes the number of chromosomes in a normal human liver cell?
23 pairs of chromosomes
46 different types of chromosomes
46 male chromosomes and 46 female chromosomes
23 original chromosomes and 23 duplicate chromosomes
Genetic information usually flows in one specific direction. Which of the following best represents this flow?
DNA → Protein → RNA
Protein → RNA → DNA
RNA → Protein → DNA
DNA → RNA → Protein
DNA and RNA are similar because they both contain
deoxyribose
nucleotides
thymine
double helices
What process does this diagram represent?
mutation
respiration
transcription
translation
Why is the particular sequence of bases in a segment of DNA important to cells?
Some base sequences code for protein production.
Some base sequences cause the release of lipids from the nucleus.
Some base sequences contain the order of sugars in polysaccharides.
Some base sequences produce electrical signals sent to the cytoplasm.
Which of the following statements best describes a DNA molecule?
It is a double helix.
It contains the sugar ribose.
It is composed of amino acids.
It contains the nitrogenous base uracil.
Which of the following units are repeatedly joined together to form a strand of DNA?
amino acids
fatty acids
nucleotides
polysaccharides
In a molecule of double-stranded DNA, the amount of adenine present is always equal to the amount of
cytosine.
guanine.
thymine.
uracil.
Which of the following models most accurately represents the structure of DNA?
[Diagram A]
[Diagram B]
[Diagram C]
[Diagram D]
Look at the illustration below. This illustration is a model of
RNA
DNA
a lipid
a protein
DNA from four organisms was examined using gel electrophoresis. According to the data, which of these pairs of organisms are most closely related?
1 and 2
2 and 3
2 and 4
3 and 4
What do the G and A represent in the DNA sequence?
sugars
amino acids
phosphates
nitrogen bases
How many nucleotides are needed to code for one amino acid?
1
3
4
6
Which RNA sequence is produced using the DNA sequence AGC-TAC-ACT?
UCG-AUG-UGA
UCG-UAC-ACU
TCG-ATG-TGA
AGC-UAC-ACU
Which of these are the repeating units that form a DNA molecule?
fatty acids
nucleotides
amino acids
chromosomes
Hemoglobin is an important protein in red blood cells. The DNA code for hemoglobin contains the following segment: TGC-GGA-CTC-CTC. Which of these is the messenger RNA code for this segment of DNA?
ACG-CCT-GAA-GAA
TCC-GGT-CTC-CTC
ACG-CCU-GAG-GAG
UGC-GGA-CUC-CUC
According to the diagram, in which step is messenger RNA being constructed?
A. I
B. II
C. III
D. IV
Which step involves transfer RNA?
I
II
III
IV
Which step involves ribosomes?
I
II
III
IV
A researcher recently discovered a species of bacteria. DNA sequences were obtained from it and from several other species of bacteria. The DNA sequences came from the same part of the bacterial chromosome of each species. DNA Sequence Unknown Species: ACT GCA GCC Species I: ACA GCG CCG Species II: ACT GCT GGC Species III: ACA GCC GGG Species IV: ACT GCA GCG According to the data above, the unknown bacteria are most closely related to which species?
Species I
Species II
Species III
Species IV
Which of the following is correctly matched with its function?
rRNA – contains codes to make new ribosomes
DNA – carries the amino acids to the ribosomes
tRNA – combines with proteins to make up ribosomes
mRNA – carries genetic codes from nucleus to the ribosomes
Scientists can insert and remove nucleotides from a DNA strand. Which of these identifies this process?
base pairing
gene splicing
DNA synthesis
DNA transcription
Which of these represents the structure of messenger RNA?
[Diagram of double helix]
A C G A A A C G C G T A
C G G U G U G C M C M A
Proline Valine Glycine Serine
A strand of DNA has a nucleotide base sequence of TAC-CGG-AGT. Which of the following is the complementary mRNA nucleotide sequence produced from the strand of DNA?
UAC-CGG-AGU
ACU-GAA-CGA
AGU-UCC-UAC
AUG-GCC-UCA
A cellular process uses a strand of genetic material to produce a new strand. Parts of the strands are shown below. Original strand ATT CAG New strand UAA GUC This new strand will most likely be used for
gene splicing
DNA synthesis
crossing-over
protein synthesis
The genetic information for making a protein must move from the nucleus to the cytoplasm. Which of these moves this information to the cytoplasm?
a ribosome
DNA
RNA
an amino acid
Which of these is a nucleotide?
1
2
3
4
Which of these is a sugar?
1
2
3
4
The nucleotide base sequence of a strand of DNA is TAC-CCG-AGT. What is the sequence of the complementary DNA strand?
TAC-CCG-AGT
ACT-GAA-CGA
AGT-TCC-TAC
ATG-GCC-TCA
Which of these make up the primary link between a gene and the expression of a trait?
proteins
sugars
lipids
vitamins
Scientists have determined the sequence of most of the human genome. Which of these fields of science will probably benefit the most from this knowledge?
chemistry
geology
physics
medicine
Which was most likely introduced into corn that made it pest-resistant?
gene
lipid
toxin
protein
Both DNA and RNA
contain phosphate
contain amino acids
are a double helix
are inorganic
Based on this information, which two species are most closely related?
the American black bear and the giant panda
the American black bear and the raccoon
the red panda and the raccoon
the red panda and the giant panda
What does DNA sequencing most help taxonomists learn about an organism?
how the organism reproduces
how the organism interacts with its environment
how the organism is related to other species
how the organism fits into the food chain
Which statement best describes a gene?
A gene contains a code for building a carbohydrate.
A gene contains chromosomes inherited during sexual reproduction.
A gene is a segment of protein in the nucleus.
A gene contains a code for building a protein.
The diagram below explains why offspring are more similar to their parents than to other organisms, even though all organisms are made of the same basic substances. Which statement is the best information to include in the third box in the diagram?
RNA is a substance that forms a copy of the DNA.
Every different sequence of amino acids makes a unique protein.
Proteins vary in structure more than any other type of organic molecule.
DNA consists of carbon, hydrogen, oxygen, nitrogen, and phosphorus atoms.
Which trait will the offspring get from the parent beaver?
Eating bark from a tree
Sitting under a tree
Having a flat tail
A strand of DNA is exposed to intense heat. Which of these best describes what will happen to the strand of DNA?
The chemical bonds of the DNA molecule will be broken.
More nitrogen base pairs will add on to the DNA molecule.
The chemical bonds of the DNA molecule will be strengthened.
The nitrogen base pairs in the DNA molecule will switch places.
What is the role of hydrogen bonds in the structure of DNA?
to code for proteins
to synthesize proteins
to separate the strands
to connect the base pairs
Which of these best describes the initial change caused by a DNA mutation?
a change in the sequence of base pairs
a change in the production of enzymes
a change in the number of nucleosomes within a cell
a change in the number of hydrogen bonds between the bases
Which of these shows the steps by which proteins are coded and synthesized?
RNA → DNA → protein
DNA → RNA → protein
protein → RNA → DNA
protein → DNA → RNA
The chromosome structure in a cell accounts for genetic variation based on the order of its
sugar groups
nitrogen bases
hydrogen bonds
phosphate groups
Which of the following is related to a chromosome in a way similar to how a bone is related to a skeleton?
A. A nucleus
B. A gamete
C. A gene
D. A cell
Scientists can genetically alter corn so that it makes a protein that will harm a certain caterpillar that feeds on it. Which of the following is an advantage of producing this type of corn?
The corn will have a better color.
The corn will be able to resist insects.
The insects will reproduce more quickly.
The insects will become immune to the poison.
What would the mRNA complement of the above DNA strand be?
A. AATGCA
B. GGCAUG
C. TTACUT
D. UUACGU
In what part of DNA is genetic information located?
Hydrogen bonds
Nucleotide sequence
Sugar molecules
Enzymes
Watson and Crick’s model of DNA resembles—
interlocking gears.
a boat on a calm lake.
a twisted ladder.
electrical wires.
What structures carry the most genetic information for a leaf cell?
Chromosomes
Ribosomes
Centrioles
Chloroplasts
One way RNA is different from DNA is that RNA contains—
phosphate groups.
hydrogen bonds.
ribose.
bases.
What is photographed to create a karyotype?
Mutations
Genes
Gametes
Chromosomes
Which of the following statements best explains the relationship between the parts of genetic materials?
Each DNA molecule contains genes.
Each gene contains many DNA molecules.
Each DNA molecule contains many chromosomes.
Each chromosome contains DNA molecules.
Which of the following represents a tRNA complement to the codons above?
UAGTGA
ATCACT
AUGACU
TACTCA
Which of the following best describes the order of events that leads to genetic expression?
DNA → RNA → amino acid → protein → genetic expression
RNA → amino acid → DNA → protein → genetic expression
DNA → amino acid → protein → RNA → genetic expression
RNA → protein → DNA → amino acid → genetic expression
What is the region on the chromosome shown above marked by the letter 'Q'?
Chromatin
Centromere
Centriole
Centrosome
Which of these models best represents a DNA molecule?
[Image of double helix]
[Image of parallel lines with circles]
[Image of hexagonal shapes]
[Image of circles connected by dashed lines]
DNA that has been cut by enzymes can separate into segments of different lengths during the process of—
mitosis.
electrophoresis.
gene amplification.
cytokinesis.
The bacterium Agrobacterium tumefaciens infects plants, and a portion of its DNA is inserted into the plant’s chromosomes. This causes the plant to produce gall cells, which manufacture amino acids that the bacterium uses as food. This process is a natural example of
polyploidy.
genetic manipulation.
grafting.
hybridization.
Genetic engineering has produced goats whose milk contains proteins that can be used as medicines. This effect was produced by
mixing foreign genes into the milk.
injecting foreign genes into the goats’ udders.
inserting foreign genes into fertilized goat eggs.
genetically modifying the nutritional needs of the goats’ offspring.
Mutations within a DNA sequence are
natural processes that produce genetic diversity.
natural processes that always affect the phenotype.
unnatural processes that always affect the phenotype.
unnatural processes that are harmful to genetic diversity.
A substitution of thymine with adenine in one DNA codon causes a particular disorder. Which statement explains how the change in DNA leads to this disorder?
The deletion mutation prevents the production of the hemoglobin protein in the body.
The frameshift mutation prevents the production of several proteins found in the blood.
The insertion mutation causes extra hemoglobin proteins to attach to red blood cells.
The point mutation causes a different amino acid to be added to the hemoglobin protein.
A rare genetic condition causes dwarfism and immunodeficiencies. Which of the following is the most likely cause of this condition?
a parasitic infection
a mutation in DNA
a bacterial disease
an excess of ATP
Which of the following best describes the result of a mutation in an organism's DNA?
The mutation may produce a zygote.
The mutation may cause phenotypic change.
The mutation causes damage when it occurs.
The mutation creates entirely new organisms.
In phenylketonuria (PKU), an enzyme that converts one amino acid into another does not work properly. Which of the following is the most likely cause of this genetic condition?
an error in the transcription of the gene for the enzyme
a mutation in the DNA sequence that codes for the enzyme
an excess of the amino acids necessary to produce the enzyme
a structural variation in the amino acid modified by the enzyme
The box below contains a statement about mutations. In many cases throughout geologic history, if mutations in the genetic material of existing species had not occurred, new species would not have appeared. Which of the following conclusions about mutations in the DNA sequence of a gene is most consistent with the statement?
Mutations are always rapidly occurring.
Mutations are always beneficial.
Mutations are the only way new species arise.
Mutations are an important mechanism for the evolution of new species.
A hereditary muscular disease in horses causes abnormal opening and closing of the sodium ion channels in the muscle cells. Which of the following statements describes the most likely origin of this disease?
A virus evolved specifically to attack the muscle cells of horses.
Motor neurons near some of the muscle cells degenerated over time.
High levels of sodium in the blood irreversibly damaged the ion channels.
A mutation occurred in the gene coding for the sodium ion channel protein.
Huntington’s disease (HD) is a hereditary disease that destroys brain cells. In individuals with HD, the functioning of a specific protein is altered, and this leads to the disease’s effects. Which of the following is the most likely cause of the altered protein function in individuals with HD?
a mutation in the DNA sequence that codes for the protein
an increase in the amount of fat rather than protein in the diet
a decrease in the amount of glucose and amino acids in the blood
a structural abnormality in the endoplasmic reticulum of brain cells
During DNA replication, the wrong nucleotide was inserted in the DNA sequence. Which of the following terms describes this situation?
mutation
regeneration
transcription
translation
Crossing-over most commonly results in
new species
new populations
new combinations of genes
new numbers of chromosomes
What technology was made possible by the discovery of the structure of DNA?
organ transplants
antibiotic production
gene splicing
artificial fertilization
Scientists have altered crop plants to make them more resistant to insects and disease. Which of these processes makes it possible for scientists to alter plants?
natural selection
gene splicing
adaptation
chemosynthesis
Which of these is an environmental factor that causes damage to chromosomes?
acid rain
lead paint
methane gas
ultraviolet light
Which of these describes a mutation that can be inherited?
random breakage in a liver cell’s DNA
abnormal lung cells produced by toxins in smoke
a nitrogen base substitution in a gamete cell
ultraviolet radiation damage to skin cells
Which of these results when one nitrogen base replaces another in a segment of genetic material?
an enzyme substrate
a mutation
a feedback loop
an adaptation
A rare disorder is caused by changes in a gene. Parents of individuals with the disorder have only normal copies of this gene. Which of these most likely causes this disorder?
mitosis
gene splicing
mutation
natural selection
Certain plant crops are genetically engineered to grow faster and resist disease. These genetically engineered plant crops cannot reproduce because they have a “terminator” gene that keeps their seeds from sprouting. However, once the genetically engineered plant crops are planted outside, they may cross-pollinate with unaltered plant crops. The use of terminator genes is least likely to result in
increased costs for seeds
decreased varieties of food
terminator genes spreading to other crops
scientists being harmed from working with the terminator genes
In the laboratory, scientists remove the gene for insulin from human chromosomes. They insert the gene into the DNA of bacteria. This causes the bacteria to produce human insulin. The insulin is used to treat diabetes in humans. Which of these describes this process?
meiosis
fertilization
gene splicing
DNA fingerprinting
Two segments of DNA are shown in the diagram below. Normal thymine (T) is found in the old strand. It is replaced by an abnormal molecule (T*) in the new strand. The abnormal molecule (T*) binds to guanine (G) instead of binding to adenine (A). This is an example of
an adaptation
protein synthesis
a mutation
binary fission
Most bacteria do not have the ability to break down oil that is accidentally spilled into the ocean by tankers. However, scientists can insert a gene into the DNA of a bacterium to give it the ability to break down the oil. This technology is an example of
crossing-over
DNA replication
gene splicing
translation
When the segment of human DNA that codes for insulin production is inserted into bacterial DNA, the bacterium begins producing human insulin. Which of these best identifies the process by which human DNA is inserted into bacterial DNA?
gene splicing
crossing-over
mutation
cloning
Scientists can genetically alter corn so that it makes a protein that will harm a certain caterpillar that feeds on it. Which of the following is an advantage of producing this type of corn?
The corn will have a better color.
The corn will be able to resist insects.
The insects will reproduce more quickly.
The insects will become immune to the poison.
Risks of having genetic mutations are increased with excessive exposure to—
high air pressure.
high humidity.
ultraviolet rays.
oxygen.
Red blood cells contain the protein hemoglobin which aids in transportation of the respiratory gases. Most humans have a form of hemoglobin called hemoglobin A. Individuals with sickle cell anemia have a very similar form called hemoglobin S. This hemoglobin is slightly changed in shape and has a reduced ability to transport oxygen. It is the presence of hemoglobin S that results in the signs and symptoms of sickle cell anemia. Which of the following is the expected cause of the production of hemoglobin S?
Translocation of a chromosome
Deletion of part of a chromosome
Duplication of the hemoglobin A gene
A point mutation of the hemoglobin A gene
A botanist inserts a new gene sequence into a pink-flowering plant. He hopes that the genetically modified plant will now produce blue flowers. In nature, which of the following processes would result in this kind of change?
Grafting
Mutation
Photosynthesis
Transpiration
Which of the following chromosome pairs contain the above chromosomes after crossing over is complete?
A. [diagram]
B. [diagram]
C. [diagram]
D. [diagram]
The table shows a mutation in a DNA sequence. Original Sequence: GCA TAGT GCT ATA GCG ACT Mutated Sequence: GCA TTC CTA TAG CGA CT What is the result of this mutation during the translation process?
The translation process will fail to begin.
The mRNA will be translated at a faster rate than normal.
Everything after the mutation will be translated incorrectly.
Some of the proteins formed during translation will be unstable.
Which genetic abnormality can be identified through karyotyping?
point mutation
recessive allele
extra chromosome
sex-linked allele
Which would best allow a species to survive environmental changes?
similar physical features
low mutation rate
small population
genetic diversity
Which would most likely produce a mutation that is passed on to offspring?
radiation changing the DNA sequence in skin cells
a gamete with an extra chromosome forming
tobacco smoke altering the genes in lung cells
exposure to chemicals altering nerve cell function
Which will most likely cause variations to occur within a species?
competition
mutation
mutualism
predation
Instead of using chemicals to destroy some insects, scientists are now able to produce a type of corn that will repel insects. How are scientists able to produce this type of corn?
by not spraying the corn plants
by soaking corn seeds in insect spray
by changing the genetics of the corn plants
Which will most likely cause a gene to mutate?
water
radiation
soil
A mutation occurs in the genes that code for coat color in deer. Which change will most likely result from this mutation?
a change in the selection pressures acting on coat color
a change in the coat-color genes of deer predator species
an increase in coat-color diversity in the population
an increase in the number of genes for coat color in the population
This chart shows a list of messenger RNA codons. A strand of DNA with the sequence AAC AAG CCC undergoes a mutation, and the first A is changed to a C. How will this mutation affect the amino acid sequence?
One amino acid will change.
Two amino acids will change.
All of the amino acids will change.
The amino acids will remain the same.
Which of these would most likely cause a mutation?
the placement of ribosomes on the endoplasmic reticulum
the insertion of a nucleotide into DNA
the movement of transfer RNA out of the nucleus
the release of messenger RNA from DNA
One human disease is caused by a change in one codon in a gene from GAA to GUA. This disease is the result of
a mutation.
a meiosis error.
crossing-over.
polyploidy.
This segment of DNA has undergone a mutation in which three nucleotides have been deleted. A repair enzyme would replace them with
CGT.
GCA.
CTG.
GTA.
Radon is a radioactive gas that is sometimes present in homes. If radon is inhaled, its decay products are deposited in the lungs. Radioactive particles can penetrate cells and cause changes to the cells' DNA. These changes in DNA are an example of which of the following?
homeostasis
mitosis
mutation
transcription
People who inherit hemophilia type A are unable to make a protein required to clot blood. This disorder is directly related to which of the following?
A mutation in one gene
A chromosome that is duplicated
A gene that was incorrectly copied
A trait acquired from the environment
What is the mode of inheritance shown in the pedigree?
A. Autosomal dominant
B. Autosomal recessive
C. Sex-linked carried on the X chromosome
D. Sex-linked carried on the Y chromosome
The pedigree below shows the transmission of a disorder within a family. Which statement describes the offspring that would result if individual 1 has children with a woman that does not carry the allele for this disorder?
None of the daughters will inherit the allele for the disorder.
All of the sons will inherit the allele for the disorder.
All of the daughters will be affected by the disorder.
None of the sons will be affected by the disorder.
One of the dogs has progressive retinal atrophy, a condition that damages the retina. What are the genotypes of dog 1 and dog 2?
Dog 1 is aa and dog 2 is aa.
Dog 1 is aa and dog 2 is Aa.
Dog 1 is Aa and dog 2 is Aa.
Dog 1 is AA and dog 2 is Aa.
What is the genotype of individual 6?
XHXH
XHXb
XHY
XbY
How would overexposure to X-rays affect most animal cells?
It would increase cell specialization in organs.
It would change the sequence of DNA nucleotides in affected cells.
It would produce new nucleotides for DNA molecules.
It would cause an increase in red blood cell production.
A genetic mutation resulted in a change in the sequence of amino acids of a protein, but the function of the protein was not changed. Which statement best describes the genetic mutation?
It was a silent mutation that caused a change in the DNA of the organism.
It was a silent mutation that caused a change in the phenotype of the organism.
It was a nonsense mutation that caused a change in the DNA of the organism.
It was a nonsense mutation that caused a change in the phenotype of the organism.
Which stage in the diagram shows the separation of the original DNA molecule into two complementary strands?
A) Stage 1
B) Stage 2
C) Stage 3
D) None of the above
Fill in the blank: The letters __, __, __, and __ represent the four nucleotides in DNA.
A, T, C, and G
A, U, C, and G
A, T, U, and G
A, T, C, and U
After DNA replication, the result is two complete DNA molecules.
True
False
A partial DNA sequence for normal hemoglobin and a partial DNA sequence for sickle-cell anemia are shown below. G-G-A-C-T-T-C-T-T Normal hemoglobin G-G-A-C-A-T-C-T-T Sickle-cell anemia Based on the DNA sequences, sickle-cell anemia is caused by
a sex-linked trait
a dominant nucleotide
a mutation in the genetic code
an incomplete separation of chromosomes.
The chromosome numbered 1 through 22 are known as
ribosomes
lysosomes
centrosomes
autosomes
The preparation of these charts for individuals A and B is known as
microsurgery
karyotyping
blood typing
chemical screening.
Which genetic disorder in individual A is indicated by the number of chromosomes labeled 21?
phenylketonuria (PKU)
Tay-Sachs
sickle-cell anemia
Down's syndrome.
A change in the sequence of nitrogenous bases in DNA may result in
a gene mutation
sex linkage
polyploidy
nondisjunction.
A change that alters the base sequence in an organism's DNA is called a
synapsis
mutation
disjunction
replication.
Down syndrome is a genetic disorder caused by the presence of an extra chromosome number 21 in the body cells of humans. This extra chromosome most likely is a result of
mitotic cell division in the brain
development of an unfertilized egg
multiple allelic pairs of genes
nondisjunction during meiosis
Select the technique, chosen from the list below, that is best described by the statement shown. This technique involves the use of a photograph to study the homologous pairs of chromosomes of an individual in order to detect genetic disorders.
Chemical analysis of body fluids
Cloning
Genetic engineering
Karyotyping
Certain genetic disorders can be detected by preparing and studying an enlarged photograph of paired chromosomes from a cell. The preparation of this photograph is known as
genetic screening
karyotyping
genetic counseling
amniocentesis
The diagram shown represents a photographic enlargement of replicated chromosomes from a fetal cell. For which technique would this photograph be used to determine if the chromosomes of the fetus exhibit any genetic abnormalities?
cleavage
plasmolysis
chemosynthesis
karyotyping
Down syndrome in humans may result from
the presence of an extra chromosome in a zygote
the absence of a single chromosome in a zygote
a mutation of one gene in a zygote
failure of a chromosome to replicate in a zygote
X rays, formaldehyde and asbestos fibers are all similar in that they are
animal preservatives
used to treat diseases
used to diagnose diseases
mutagenic agents
The preparation of an enlarged photograph showing paired homologous chromosomes is known as
amniocentesis
blood screen
karyotyping
urine analysis
An analysis of chromosomes may show the loss of a portion of a chromosome. This type of chromosomal change is known as
nondisjunction
an addition
translocation
a deletion
The use of chemicals such as formaldehyde and asbestos has decreased because they have been
found to cause sterility in plants
replaced by more toxic chemicals
linked to uncontrolled meiotic cell division
found to increase the incidence of mutations
Select the term, chosen from the list below, that is best described by the statement shown. A photograph of paired human chromosomes is prepared.
Karyotyping
Cloning
Deletion
Translocation
Which genetic disorder is usually detected by analyzing a karyotype?
phenylketonuria
Tay-Sachs
Down syndrome
sickle-cell anemia
Select the genetic technique, chosen from the list below, that is best described by the statement shown. Enlarged photographs of homologous chromosomes are prepared for examination to detect chromosomal defects.
Screening
Karyotyping
Cloning
Genetic engineering
The diagram represents a
deletion
synapsis
karyotype
disjunction
The chromosomes are arranged to show
homologus pairs
tetrads
independent assortment
nucleotides
The individual from whom these chromosomes were taken is a
male
female
hermaphrodite
polyploid
This chromosomal arrangement indicates that the individual has
phenylketonuria
Down syndrome
sickle-cell anemia
Tay-Sachs disease
Substances that increase the chance of gene alterations are known as
mutagenic agents
genetic agents
chromosomal agents
adaptive agents
In humans, Down syndrome is often a result of the
disjunction of homologous chromosomes during meiotic cell divisions
nondisjunction of chromosome number 21 in one of the parents
combination of an egg and sperm, each carrying a recessive allele for this disorder
fusion of two 2n gametes during fertilization
Which phrase best describes a human with the chromosomes represented in the diagram shown?
a female who exhibits Down syndrome
a male who exhibits Down syndrome
a female who does not exhibit Down syndrome
a male who does not exhibit Down syndrome
The technique known as karyotyping is used to detect abnormalities in
chromosomes
ribosomes
blood and urine
amniotic fluid
The addition, removal, or substitution of nitrogenous bases in a DNA molecule may be caused by
mutagenic agents
cloning
vegetative propagation
nondisjunction
Mutations can be transmitted to the next generation only if they are present in
brain cells
sex cells
body cells
muscle cells
A karyotype is shown in the diagram. Information in this karyotype indicates that the individual is a
female with sickle-cell anemia
male with Tay-Sachs disease
female with Down syndrome
male with phenylketonuria
Genetic information is shown in the diagram. This type of diagram is used to
reveal chromosome disorders
determine the number of genes in a human genotype
detect sickle-cell anemia
correct the disorder known as PKU
The arrangement of chromosomes shown in the diagram is known as
a karyotype
a urine analysis
amniocentesis
blood typing
Examination of the diagram indicates that these are the chromosomes of a
female with Down syndrome
male with Down syndrome
female without Down syndrome
male without Down syndrome
The genetic disorder shown in the diagram most likely resulted from
crossing-over
nondisjunction
polyploidy
segregation
Which technique was used to organize the chromosomes as shown in the diagram?
screening
chromatography
karyotyping
grafting
For each phrase in the following question(s), select the genetic disorder that is most closely associated with that phrase. Changes in speech patterns and mental retardation due to the presence of an extra chromosome
Tay-Sachs
Phenylketonuria
Sickle-cell anemia
Down syndrome
A single change in the sequence of nitrogenous bases in a DNA molecule would most likely result in
crossing-over
polyploidy
nondisjunction of chromosomes
a gene mutation
The chromosomes of a person with a genetic disorder are shown in the diagram below. This genetic disorder resulted from
hybridization
nondisjunction
polyploidy
segregation
Question 40.
Question 41.
Question 42.
Question 43.
Question 44.
Question 45.
Question 46.
Question 47.
Question 48.
Question 49.
Question 50. (No question text or options provided.
Question 51.
Why is artificial insemination used in breeding cattle?
It is the most economical way to produce cattle of good quality.
It results in the production of only female offspring.
It can be used at any time in the estrous cycle in cattle.
It increases the probability that advantageous mutants will develop.
Genetic engineering in corn allows genes from bacteria to be added to the genetic material of corn. In traditional breeding, genes of only closely related types of corn can be exchanged. What is one risk of genetically engineering corn plants?
decreases the amount of pesticide needed to grow corn.
increases the length of time corn can be stored before it rots
increases the chance of adding a trait to corn that causes allergies
decreases the number of corn plants a farmer can grow in a season
Which of these is best demonstrated by the experiment above?
Differentiated cells contain a complete set of genes.
All frogs are genetically identical.
Embryonic development is controlled by the cytoplasm.
The nucleus of a tadpole cell is unspecialized.
The bacterium Agrobacterium tumefaciens infects plants, and a portion of its DNA is inserted into the plant’s chromosomes. This causes the plant to produce gall cells, which manufacture amino acids that the bacterium uses as food. This process is a natural example of:
polyploidy.
genetic manipulation.
grafting.
hybridization.
Genetic engineering has produced goats whose milk contains proteins that can be used as medicines. This effect was produced by:
mixing foreign genes into the milk.
injecting foreign genes into the goats’ udders.
inserting foreign genes into fertilized goat eggs.
genetically modifying the nutritional needs of the goats’ offspring.
Two farmers plant different varieties of corn on neighboring farms. Farmer A plants genetically modified corn. Farmer B plants a non-modified variety of corn. What would be farmer B’s primary concern if she plans to gather seed for next year’s crop?
loss of genetic variability in the non-modified variety
that mutation rates will increase in the non-modified variety
that insects will only pollinate the genetically modified corn
unintended transfer of modified genes to her crop by cross-pollination
DNA from four organisms was examined using gel electrophoresis. The results are shown in the diagram below. According to the data, which of these pairs of organisms are most closely related?
A. 1 and 2
B. 2 and 3
C. 2 and 4
D. 3 and 4
Scientists create “transgenic” organisms when they transfer genes from one organism to a different kind of organism. Many people marvel at this technology, while others are concerned about its consequences and its effects on society. Which of these is not a realistic concern about the formation of “transgenic” organisms?
Transgenic plants may produce chemicals that are harmful to wildlife.
Humans will acquire harmful transgenic traits by consuming transgenic foods.
Eating fruit from transgenic plants could trigger allergies in sensitive individuals.
This technology may be misused or unintentionally used to make products harmful to humans and other organisms.
What technology was made possible by the discovery of the structure of DNA?
organ transplants
antibiotic production
gene splicing
artificial fertilization
Which of these is not a use for DNA fingerprinting?
to determine how individuals are related
to make messenger RNA
to determine a genetic sequence
to study inherited diseases
Certain plant crops are genetically engineered to grow faster and resist disease. These genetically engineered plant crops cannot reproduce because they have a “terminator” gene that keeps their seeds from sprouting. However, once the genetically engineered plant crops are planted outside, they may cross-pollinate with unaltered plant crops. The use of terminator genes is least likely to result in
increased costs for seeds
decreased varieties of food
terminator genes spreading to other crops
scientists being harmed from working with the terminator genes
A scientist cloned a goat. Which of these is a true statement about the cloned goat?
It has new genes and traits.
It lacks the genes for reproduction.
It has genes that are identical to the original goat.
It looks the same as the original goat but has different genes.
Scientists have determined the sequence of most of the human genome. Which of these fields of science will probably benefit the most from this knowledge?
chemistry
geology
physics
medicine
Which was most likely introduced into corn that made it pest-resistant?
gene
lipid
toxin
protein
When the segment of human DNA that codes for insulin production is inserted into bacterial DNA, the bacterium begins producing human insulin. Which of these best identifies the process by which human DNA is inserted into bacterial DNA?
gene splicing
crossing-over
mutation
cloning
Certain disorders, such as sickle cell anemia, are linked to specific genes. Some scientists would like to use gene therapy to cure such disorders. Gene therapy involves replacing the nonworking cells with cells that have been genetically altered. Which of these is a logical argument against gene therapy?
A. Changing one gene may negatively affect other genes.
B. Changing one gene may lead to the formation of a new species.
C. Scientists may not be able to distinguish one gene from another.
D. Drugs may already exist to cure these diseases, so there is no need for risky therapy.
Which of these is an example of selective breeding?
Cutting a stem from a plant so that a new plant grows from the stem
Taking a skin cell from a sheep and making an exact clone of the sheep
Replacing DNA of a plant with DNA that allows the plant to grow in little water
Selecting two horses and having them mate in order to produce stronger offspring
Sean is studying the advantages of selective breeding in plants. He made the following list of possible advantages: 1) Can produce corn that attracts grasshoppers 2) Can develop grass that can grow with less water 3) Can develop wheat that can grow in different types of soil 4) Can produce oranges that are not affected by freezing temperatures Which items on the list provide logical arguments in favor of selective breeding?
1, 2, 3
2, 3, 4
2, 4
3, 4
Scientists want to create citrus trees that are tolerant of cold weather. Currently, if the fruit from a citrus tree has not been picked and a freeze occurs, the fruit is damaged and cannot be sold. The scientists are studying how to alter the tree’s cells so that they are not damaged by the freezing temperatures.
Plants that can tolerate the cold would be less likely to become infected by fungi.
Plants that can tolerate the cold could allow citrus trees to grow in colder climates.
The research could make it easier to preserve the picked fruit during storage and shipping.
The research could help scientists alter human cells so that human skin is not damaged by frostbite.
Scientists at a research center are studying plants that have a natural resistance to insects. Which of these is a logical justification for continuing this research?
Insect-resistant plants grow faster than plants that are not insect resistant, making larger-producing crops.
Studying the genes of insect-resistant plants could help in the development of crops resistant to insects.
Finding these genes could help lead to finding the genes that allow a plant to survive with little water.
The research could lead to development of new kinds of food crops with different nutrients.
Scientists found an organism that can live without water for long periods of time. The scientists made copies of its DNA, then injected this new DNA into corn.
Cloning
Selective breeding
Genetic engineering
Asexual reproduction
A bacterium, Bacillus thuringiensis (Bt), makes a toxin that destroys the larvae of insects that threaten corn crops. Scientists engineered corn plants, known as Bt-corn. Bt-corn can make a toxin to destroy the larvae that eat the corn.
Bt-corn pollen may harm helpful insects that pollinate the corn, such as bees.
Bt-corn kernels may attract unwanted animals that can damage the crop, such as crows.
Bt-corn plants use much less pesticide than unmodified corn plants.
Bt-corn seed is more expensive than unmodified corn seed.
Which activity is an example of selective breeding?
Collecting wild saplings from a forest and replanting them
Cross-pollinating plants that produce large numbers of fruit
Allowing a population of laboratory mice to mate randomly
Raising sheep that have been cloned from adult sheep tissues
A single isolated gene can be cloned most rapidly using genetically engineered—
bacteria.
nematodes.
sea anemones.
pea plants.
The diagram below represents DNA fingerprints which are the result of gel electrophoresis done on several DNA samples found at a crime scene. Which suspect is linked to the crime scene by this DNA analysis?
A. Suspect A
B. Suspect B
C. Suspect C
D. Suspect D
As scientists have developed more productive crop varieties, farmers have switched from growing many traditional varieties to new high-yield varieties. For example, in India, the 10,000 varieties of rice once grown have been reduced to 10 major ones for most of the rice crop. Besides the varieties of rice being reduced, what else is reduced by this practice?
types of soil nutrients
the gene pool for rice
food chains that include rice
human dietary choices
This diagram represents samples of DNA that were cut with a restriction enzyme during DNA fingerprinting in a crime lab. Which technique was used to produce these bands?
cloning
gel electrophoresis
gene splicing
genetic engineering
Which is the best way to determine if two people are genetically related?
DNA fingerprinting
blood typing
karyotyping
Use the circle graphs below to answer the question. Changes in Allele Frequency Over Time The graphs illustrate change in a lizard population over time. Which process most likely led to the change in the lizard population?
natural selection acting on a harmful trait
natural selection acting on a beneficial trait
natural selection acting on a dominant trait
natural selection acting on a recessive trait
The diagram below shows the procedure scientists used to clone a frog from the nucleus of a skin cell. The tadpole produced by the cloning process will be genetically ________.
most similar to the frog the egg cell came from
most similar to the frog the skin cell came from
different from both frogs that the cells came from
identical to both frogs that the cells came from
