WorksheetsCoagulation Pathways Quiz
Total questions: 20
Worksheet time: 10mins
Blood coagulation is best defined as
Conversion of fibrin into fibrinogen
Conversion of liquid blood into a solid clot
Aggregation of platelets
Lysis of blood cells
Which is the first factor activated in the intrinsic pathway?
Factor XI
Factor IX
Factor XII
Factor X
The intrinsic pathway is also called
Tissue factor pathway
Contact activation pathway
Final common pathway
Platelet pathway
The extrinsic pathway is initiated by
Exposure of collagen
Platelet aggregation
Release of tissue thromboplastin
Activation of factor XII
Tissue thromboplastin is also known as
Factor II
Factor IV
Factor III
Factor VII
Which factor is common to both intrinsic and extrinsic pathways?
Factor VIII
Factor IX
Factor X
Factor XII
Formation of prothrombin activator occurs in
Only intrinsic pathway
Only extrinsic pathway
Only common pathway
Both intrinsic and extrinsic pathways
Conversion of prothrombin to thrombin requires
Factor XII
Prothrombin activator
Fibrinogen
Factor XIII
Which factor converts fibrinogen into fibrin?
Prothrombin
Thrombin
Factor X
Factor XIII
Stabilization of fibrin clot is done by
Factor V
Factor VIII
Factor X
Factor XIII
Calcium is designated as
Factor III
Factor IV
Factor V
Factor VII
Which of the following is vitamin K dependent?
Factor V
Factor VIII
Factor IX
Factor XII
The fastest pathway of coagulation is
Intrinsic pathway
Extrinsic pathway
Common pathway
Platelet pathway
Time taken for extrinsic pathway activation is approximately
1–6 minutes
5–10 minutes
15–30 seconds
10–15 seconds
Which test assesses the intrinsic pathway?
PT
BT
aPTT
CT
Which test assesses the extrinsic pathway?
aPTT
Bleeding time
Prothrombin time
Clot retraction time
Factor VIII deficiency causes
Hemophilia A
Hemophilia B
Von Willebrand disease
Christmas disease
Which factor acts as a cofactor for factor IXa?
Factor V
Factor VIII
Factor X
Factor XI
Thrombin has a positive feedback effect on
Factors I and II
Factors V and VIII
Factors IX and X
Factors XII and XIII
Final stable clot formation requires
Fibrinogen only
Thrombin only
Fibrin with factor XIII
Platelets only
