NEW
Font size
WorksheetsPathphysio 1 101- 125
Total questions: 25
Worksheet time: 13mins
What is the missing link in the pathogenesis of endemic goiter: Iodine deficiency → decreased synthesis of thyroid hormones (T3, T4) → decreased concentration of T3, T4 in the blood →? → hyperplasia of the thyroid gland:
increased secretion of thyrotropin
increased secretion of somatostatin
increased secretion of somatomedins
decreased secretion of thyroliberin
decreased secretion of corticoliberin
Where is the pathological process localized?
pituitary gland
hypothalamus
cerebral cortex
thalamus
thyroid gland
What manifestation of hypothyroidism is typical for childhood?
mental retardation
accelerated physical development
early closure of growth zones
early closure of fontanelles
premature puberty
The missing link in the pathogenesis of hyperpigmentation of the skin and mucous membranes in Addison's disease: Cortisol deficiency → by a feedback mechanism, increased secretion of …? → increased deposition of melanin in the skin and mucous membranes → hyperpigmentation
ACTH
ADH
STH
TSH
LH
In gigantism, after immunohistochemical examination, the most common is
somatotropinoma
prolactosomatotropinoma
prolactinoma
adenomas secreting GH, LH, FSH
pheochromocytoma
In the pathogenesis of this hyperglycemia, the most important is:
activation of gluconeogenesis
activation of lipogenesis
activation of glycogenogenesis
inhibition of glycogenolysis
inhibition of lipolysis
In the development of polyuria in the diabetes insipidus, an important role is played by:
activation of the sympathoadrenal system
development of secondary aldosteronism
calcium metabolism disorder
increased permeability of aquaporins
glycosuria
The main link in the pathogenesis of Cushing's disease is:
decreased ACTH levels
decreased sensitivity of hypothalamic-pituitary system to corticosteroids
development of severe electrolyte disturbances
development of invasive pituitary macroadenoma
hyperglycemia
Thyroid cells that secrete thyroxine and triiodothyronine are called:
parafollicular cells
A cells
D cells
C cells
B cells
Hyperthyroidism is caused by increased production of thyroid hormones in:
chronic autoimmune thyroiditis
subacute thyroiditis
postpartum thyroiditis
Graves' disease
myxedema
What will a blood hormone test reveal?
increased cortisol, decreased ACTH
increased cortisol and ACTH
decreased cortisol and ACTH
increased aldosterone and ACTH
decreased cortisol, increased ACTH
Laboratory blood tests will reveal:
decreased TSH, increased T4, TSH receptor antibodies
increased TSH and T4, thyroglobulin antibodies
decreased TSH and T4
increased ACTH and cortisol
increased ACTH and aldosterone
What will the patient's blood test reveal?
decreased cholesterol
increased glucose
increased TSH, decreased T3, T4
decreased TSH, decreased T3, T4
antibodies to TSH receptors
What will most likely be revealed by a study of blood hormones in this patient?
increased glucocorticoids and ACTH
decreased cortisol and ACTH
decreased cortisol, increased ACTH
increased thyroxine and TSH
increased aldosterone and ACTH
The leading link in the pathogenesis of ketoacidotic diabetic coma?
pronounced dehydration of cells
sharp hyperglycemia
hyperosmia of blood and intercellular fluid
significant accumulation of lactic acid
hyperketonemia and uncompensated acidosis
What is the most likely cause of the enlarged thyroid gland in this patient?
Excessive iodine intake
Lack of iodine in water and food
Hereditary disease
Thyroid tumor
Treatment with iodine
Which of the following laboratory values is most typical for hypothyroidism?
Low TSH and high T4
High TSH and low T4
High TSH and high T4
Low TSH and low T4
Normal TSH and T4
Which of the following sets of laboratory values is most consistent with the expected findings for this girl's disorder?
hypernatremia, low urine osmolarity and specific gravity
hypernatremia, high urine osmolarity and specific gravity
hyponatremia, low urine osmolarity and specific gravity
hyponatremia, high urine osmolarity and specific gravity
normal blood sodium, normal urine osmolarity and specific gravity
What changes in fat metabolism are possible in the patient?
Increased ketone body levels and normal cholesterol levels
Increased cholesterol and ketone bodies
Normal cholesterol and ketone bodies
Decreased cholesterol levels
Decreased ketone bodies
What caused the occurrence of these symptoms in this case?
diabetes insipidus
nephrogenic diabetes insipidus
insulin resistance
diabetes mellitus type 1
diabetes mellitus type 2
Which of the following is the MOST important non-immune mechanism of chronic renal failure progression?
reduced load on functioning nephrons
suppression of the kallikrein-kinin system activity
compensatory hyperfiltration in intact nephrons
reduced formation of cytokines and oxygen free radicals
production of autoantibodies against glomerular basement membrane antigens
Which of the following is the MOST important in the pathogenesis of uremia?
impaired filtration and removal of nitrogenous waste from the body
hyperosmolal hyperhydration
development of alkalosis
dehydration of the body
hypercalcemia
Which of the following is the MOST likely complication of hereditary renal phosphate diabetes?
hyperphosphatemia
decreased urinary phosphorus excretion
decreased urinary calcium excretion
demineralization of bone tissue
hyperglycemia
Which of the following is the MOST likely cause of proximal tubular acidosis?
increased ammoniogenesis
decreased tubular secretion of hydrogen ions
excessive reabsorption of sodium ions
decreased ammoniogenesis
impaired reabsorption of bicarbonates
Which laboratory indicator will MOST confirm this pathology?
decreased creatinine clearance
hyposthenuria
isosthenuria
cylindruria
glucosuria
