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pathphysio 2 20-35

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

The patient has a cough with a sputum of a rusty color, pain in the right side of the chest when breathing, tachypnea, fever. He fell ill acutely. On auscultation, moist rales are heard in the area of the projection of the right lower lobe of the lung. Which is the most frequent path of penetration of microorganisms into the lung tissue in this disease?

a)

inhalation of infected aerosols

b)

spread of infection through the bloodstream

c)

spread of infection through the lymph flow

d)

microaspiration of infected secretions from the oropharynx

e)

spread of infection from neighboring affected foci

2.

A 60-year-old man was hospitalized in the clinic with complaints of shortness of breath, episodes of suffocation. With spirometry: Yellow -3.0 l, Tiffno index - 50%. After the introduction of a bronchodilator, the Tiffno index increased by 15%. When examining sputum, strands of mucus are found- "spirals". Blood test: eosinophilic leukocytosis. What is most likely to have developed in the patient?

a)

pneumonia

b)

pulmonary fibrosis

c)

bronchial asthma

d)

tuberculosis of the lungs

e)

pleurisy

3.

A 59-year-old man was admitted to the hospital with complaints of shortness of breath, episodes of suffocation associated with excruciating cough and wheezing. A functional study of the lungs revealed: VC - 3.0 liters, Tiffno index -50%. In the sputum, Kurshman's spirals are found. What mediator has the most pronounced effect on the lumen of the bronchi in this disease?

a)

leukotrienes

b)

endothelin

c)

tumor necrosis factor

d)

components of the complement system

e)

lymphokines

4.

A 56-year-old man, after suffering a myocardial infarction 4 weeks ago, complains of progressive shortness of breath, accompanied by a cough with scanty sputum streaked with blood. Which of the following is the most likely cause of the patient's current problem?

a)

pre capillary pulmonary hypertension

b)

post capillary pulmonary hypertension

c)

pulmonary hypotension

d)

primary pulmonary hypertension

e)

pulmonary thromboembolism

5.

Patient Ch. 36 years old, a worker in the mining industry, was admitted to the clinic with complaints of shortness of breath, especially pronounced during walking and physical exertion, constant cough (dry, sometimes with a small amount of sputum), chest pain. Arterial blood gas composition and spirometry data: pO2 - 92 mm Hg, pCO2 - 40 mm Hg. Oxygen capacity - 19.2% by volume Spirometry: FVC - 2.6 liters, Tiffeneau's index - 54%, MVB (% of the due value) -124.What is most likely to have developed in the patient?

a)

obstructive hypoventilation

b)

restrictive hypoventilation

c)

impaired diffusion capacity of the lungs

d)

impaired pulmonary perfusion

e)

hyperventilation of the lungs

6.

A 35-year-old male was admitted to the clinic with complaints of shortness of breath, choking, and a painful cough. Spirometry revealed: VC -3.0 l, Tiffno index -50%. In the sputum, Kurshman's spirals were found. What type of respiratory failure according to pathogenesis developed in the patient?

a)

obstructive alveolar hypoventilation

b)

restrictive alveolar hypoventilation

c)

mixed respiratory failure

d)

respiratory failure with extrapulmonary disorders

e)

centrogenic respiratory failure

7.

A 17-year-old female was admitted to the clinic in a coma. There is a smell of acetone from the mouth, blood glucose is 30 mmol/l. Breathing is deep, rare, noisy. Which of the following respiratory rhythm disorders is typical for this condition?

a)

apneustic breathing

b)

Cheyne-Stokes breathing

c)

gasping breathing

d)

Kussmaul breathing

e)

Biot breathing

8.

A 60-year-old male, a heavy smoker, complains of shortness of breath, weight loss. On examination: a patient with low nutritional status, a cylindrical chest cell, a percussion sound over the entire surface of the lungs has a boxy tint. What disease can cause these changes?

a)

emphysema

b)

pulmonary tuberculosis

c)

pneumosclerosis

d)

pneumonia

e)

bronchitis

9.

During the examination of the patient's pulmonary ventilation function, the following changes in pulmonary volumes and capacities were revealed: DV↓, MV↓, RV↓, VCF↓, OEL↓, OVC↓, Tiffno index - 90%. For which forms of pathology are such changes in indicators most likely characteristic?

a)

obstructive hypoventilation

b)

impaired diffusion capacity of the lungs

c)

impaired pulmonary perfusion

d)

restrictive hypoventilation

e)

hyperventilation of the lungs

10.

Female patient, 40 years old, was admitted to the emergency room after a suicide attempt, taking a large dose of barbiturates. At the time of examination: BP 95/65 mm Hg. Art., pulse 105 per minute. What mechanisms of respiratory center regulation disorder leading to its suppression are characteristic of this case?

a)

deficit of inhibitory afferent influences

b)

excess of inhibitory afferent influences

c)

passive hyperventilation

d)

direct damage to the respiratory center

e)

excess of excitatory afferent influences

11.

A 34-year-old man consulted his family physician with complaints of heartburn and dull nagging pains in the pelvic region on an empty stomach or at night, which disappear after a meal. From the anamnesis, the above complaints have been bothering her for 3 years and occur more often in autumn and early spring. On examination, the patient was asthenic, with moderate pallor of the skin. On palpation of the abdomen, pronounced painfulness in the epigastric region, to the right of the white line of the abdomen. What mechanism of injury is most likely to lead to the development of this pathological condition?

a)

increased synthesis of prostaglandins due to activation of cyclooxygenase

b)

increase of exocrine function of pancreas

c)

increase in pH of gastric juice

d)

Decrease of conductivity of epithelial cell apical membrane

e)

high concentration of hydrochloric acid and pepsin

12.

A 52-year-old man with complaints of weakness, malaise and moderate intermittent right-subcostal pain and scleral jaundice has hyperbilirubinemia due to direct and indirect fractions in the blood test. What enzymes increase in blood has the greatest diagnostic value in this pathology?

a)

AST, ALT

b)

LDH, alkaline phosphatase

c)

Elastase, chymotrypsin

d)

lipase, amylase

e)

creatine phosphokinase

13.

A 48-year-old woman complained of epigastric pain in the epigastric region, which was of a bandage-like nature and was accompanied by repeated vomiting. Anamnesis: she considers herself ill for 3 days and associates it with fatty cake consumption. On coprological examination, undigested inclusions of neutral fat were found. What is the leading link in the pathogenesis of this disease?

a)

activation of the kallikrein-kinin system

b)

pancreatic collapse

c)

activation of pancreatic enzymes in pancreatic tissue

d)

protein precipitate formation in pancreatic ducts

e)

hypovolemia and disruption of systemic hemodynamics

14.

A 47-year-old man, a mechanic, who complained of decreased appetite, weakness, malaise, examination revealed enlarged abdomen, "medusa head" symptom, varices in the esophagus and cardiac area of the stomach were detected during gastrointestinal examination. Blood tests revealed a platelet count of 120x109/l, prolongation of bleeding time. What is the leading link in pathogenesis of the revealed changes?

a)

platelet sequestration

b)

destruction of platelets by antibodies

c)

replacement of red bone marrow by adipose tissue

d)

iron deficiency

e)

Vitamin B12 deficiency

15.

A 42-year-old woman consulted a family physician with complaints of unpleasant feeling of rapid stomach overfilling immediately after meals, constant belching of air, sometimes with unpleasant rotten odor, decreased appetite, periodic liquid stools. From anamnesis - these complaints have been bothering me for 5-6 years, recently nausea and bloating have joined in. On examination - nutrition slightly reduced, skin of usual color. Palpation of epigastric region was moderately painful.Which of the following is most likely to cause this pathology?

a)

excessive parasympathetic stimulation of the stomach

b)

decreased secretion of secretin

c)

decreased formation of gastrin

d)

increased histamine secretion

e)

Zollinger-Ellison syndrome