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Hypersensitivity Reactions Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Hypersensitivity reactions are defined as

a)

Protective immune responses

b)

Exaggerated immune responses causing tissue damage

c)

Failure of immune system

d)

Autoimmune tolerance

2.

Type I hypersensitivity is also known as

a)

Delayed hypersensitivity

b)

Cytotoxic hypersensitivity

c)

Immune complex hypersensitivity

d)

Immediate hypersensitivity

3.

Antibody involved in Type I hypersensitivity is

a)

IgG

b)

IgM

c)

IgA

d)

IgE

4.

Cells mainly involved in Type I hypersensitivity

a)

Neutrophils

b)

Macrophages

c)

Mast cells and basophils

d)

Lymphocytes

5.

Example of Type I hypersensitivity is

a)

Serum sickness

b)

Contact dermatitis

c)

Anaphylaxis

d)

Rheumatic fever

6.

Type II hypersensitivity is mediated by

a)

IgE antibodies

b)

Immune complexes

c)

IgG or IgM against cell surface antigens

d)

T cells

7.

Mechanism involved in Type II hypersensitivity includes all EXCEPT

a)

Complement activation

b)

Opsonization

c)

ADCC

d)

Immune complex deposition

8.

Example of Type II hypersensitivity is

a)

Systemic lupus erythematosus

b)

Goodpasture syndrome

c)

Serum sickness

d)

Contact dermatitis

9.

Type III hypersensitivity is caused by

a)

IgE mediated mast cell degranulation

b)

Cell mediated immunity

c)

Immune complex deposition

d)

Autoantibodies against receptors

10.

Example of Type III hypersensitivity is

a)

Anaphylaxis

b)

Myasthenia gravis

c)

Serum sickness

d)

Contact dermatitis

11.

Arthus reaction is an example of

a)

Type I hypersensitivity

b)

Type II hypersensitivity

c)

Type III hypersensitivity

d)

Type IV hypersensitivity

12.

Type IV hypersensitivity is also called

a)

Immediate hypersensitivity

b)

Cytotoxic hypersensitivity

c)

Immune complex hypersensitivity

d)

Delayed type hypersensitivity

13.

Type IV hypersensitivity is mediated by

a)

B cells and antibodies

b)

T cells only

c)

Immune complexes

d)

Complement proteins

14.

Example of Type IV hypersensitivity is

a)

Anaphylaxis

b)

Serum sickness

c)

Contact dermatitis

d)

Goodpasture syndrome

15.

Immunity is defined as

a)

Ability to produce antibodies only

b)

Resistance to infection or disease

c)

Absence of pathogens

d)

Only innate defense

16.

Innate immunity is characterized by

a)

Antigen specificity

b)

Immunological memory

c)

Immediate response

d)

Delayed response

17.

Cells involved in innate immunity include

a)

Plasma cells

b)

T lymphocytes

c)

NK cells and macrophages

d)

B lymphocytes

18.

Physical barrier of innate immunity is

a)

Spleen

b)

Skin and mucous membranes

c)

Lymph nodes

d)

Antibodies

19.

Major mediator of innate immunity includes

a)

Antibodies

b)

Complement system

c)

MHC molecules

d)

Immunoglobulin E

20.

Inflammation is a component of

a)

Adaptive immunity only

b)

Innate immunity only

c)

Both innate and adaptive immunity

d)

Humoral immunity only