WorksheetsHemostatic Function Test
Total questions: 100
Worksheet time: 50mins
Thrombocytopenia is defined as a platelet count less than:
50,000 /μL
100,000 /μL
150,000 /μL
300,000 /μL
Thrombocytopenia is defined as:
Increase in platelet count above normal
Decrease in platelet count below normal
Deficiency of clotting factors
Prolonged prothrombin time
Thrombasthenia is:
Decrease in platelet count
Defect in platelet function
Deficiency of clotting factors
Increase in fibrinolysis
Normal bleeding time is:
30 seconds – 1 minute
1 – 3 minutes
2 – 7 minutes
10 – 15 minutes
Normal coagulation time is:
1 – 3 minutes
3 – 6 minutes
3 – 10 minutes
Hemophilia is:
An acquired platelet disorder
An inherited deficiency of coagulation factors (VIII or IX)
A disorder of platelet adhesion
Due to vitamin K deficiency
Hemophilia occurs more frequently in:
Males
Females
Both equally
Newborns only
Haemophilia type A is characterized by defect in factor:
Factor VII
Factor IX
Factor VIII
Factor X
Haemophilia type B is characterized by defect in factor:
Factor VIII
Factor IX
Factor VII
Factor X
Haemophilia type C is characterized by defect in factor:
(a)
Which clotting factor requires vitamin K for its synthesis?
Factor I (Fibrinogen)
Factor II (Prothrombin)
Factor V
Factor VIII
Vitamin K deficiency can be caused by:
Sterile intestine due to prolonged use of antibiotics
Excessive vitamin C intake
Iron deficiency
Dehydration
The most commonly used method for hemoglobin estimation in laboratories is:
Sahli’s method
Cyanmethemoglobin method
Oxyhemoglobin method
Acid hematin method
Hemoglobin concentration is usually expressed in:
mg/dL
g/dL
mmol/L
%
Which of the following is Factor X?
Factor IX
Factor XI
Factor X
Factor X
Sahli’s method estimates hemoglobin based on the formation of:
Cyanmethemoglobin
Acid hematin
Methemoglobin
Carbaminohemoglobin
Normal hemoglobin level in adult females is approximately:
8–10 g/dL
10–12 g/dL
13–14 g/dL
16–18 g/dL
The main disadvantage of Sahli’s method is:
It is time-consuming
It is expensive
It depends on visual color comparison
It requires a spectrophotometer
Hemoglobin estimation is important in the diagnosis of:
Leukemia
Thrombocytopenia
Anemia
Hemophilia
Which sample is required for hemoglobin estimation?
Serum
Plasma
Whole blood
The normal hemoglobin level in adult males (by Sahli’s method) is:
10–12 g/dL
11–14 g/dL
15–16 g/dL
18–20 g/dL
The normal hemoglobin level in adult females (by Sahli’s method) is:
9–11 g/dL
10–12 g/dL
13–14 g/dL
16–18 g/dL
Which clotting factor requires vitamin K for its synthesis?
Factor I (Fibrinogen)
Factor II (Prothrombin)
Factor V
Factor VIII
Vitamin K deficiency can be caused by:
Sterile intestine due to prolonged use of antibiotics
Excessive vitamin C intake
Iron deficiency
Dehydration
The most commonly used method for hemoglobin estimation in laboratories is:
(a)
Which of the following is the most commonly used method for estimation of hemoglobin?
Sahli’s method
Cyanmethemoglobin method
Oxyhemoglobin method
Acid hematin method
Hemoglobin concentration is usually expressed in:
mg/dL
g/dL
mmol/L
%
Sahli’s method estimates hemoglobin based on the formation of:
Cyanmethemoglobin
Acid hematin
Methemoglobin
Carbanimohemoglobin
Normal hemoglobin level in adult females is approximately:
8–10 g/dL
10–12 g/dL
13–14 g/dL
16–18 g/dL
The main disadvantage of Sahli’s method is:
It is time-consuming
It is expensive
It depends on visual color comparison
It requires a spectrophotometer
Hemoglobin estimation is important in the diagnosis of:
Leukemia
Thrombocytopenia
Anemia
Hemophilia
Which sample is required for hemoglobin estimation?
Serum
Plasma
Whole blood
Urine
The normal hemoglobin level in adult males (by Sahli’s method) is:
10–12 g/dL
11–14 g/dL
15–16 g/dL
18–20 g/dL
The normal hemoglobin level in adult females (by Sahli’s method) is:
9–11 g/dL
10–12 g/dL
13–14 g/dL
16–18 g/dL
Which of the following hemoglobin values is considered normal for a child?
6–8 g/dL
8–10 g/dL
19 g/dL
14–16 g/dL
The normal hematocrit value in adult males is approximately:
30–35%
36–40%
47%
55–65%
The normal hematocrit value in adult females is approximately:
25–30%
30–35%
42%
48–55%
A hematocrit value of 28% is most suggestive of:
Polycythemia
Dehydration
Anemia
Normal finding
Hematocrit is defined as:
Total hemoglobin concentration in blood
Percentage of red blood cells in whole blood
Number of RBCs per microliter
Volume of plasma only
In anemia, both hemoglobin level and hematocrit are usually:
Increased
Normal
Decreased
An adult male with a hemoglobin level of 18 g/dL is most likely to have:
Iron deficiency anemia
Normal finding
Polycythemia
Acute blood loss
A hemoglobin level of 6 g/dL is classified as:
Normal
Mild anemia
Moderate anemia
Severe anemia
A hemoglobin value within normal limits usually suggests:
Normal oxygen-carrying capacity
Increased plasma volume
Thrombocytopenia
Clotting factor deficiency
A hematocrit value of 32% in an adult male indicates:
Normal hematocrit
Anemia
Polycythemia
Dehydration
An increased hematocrit value is commonly seen in:
Iron deficiency anemia
Polycythemia
Acute blood loss
Unrelated
A decreased hematocrit value is commonly seen in:
Iron deficiency anemia
Polycythemia
Decreased
Unrelated
A hematocrit value of 55% is most suggestive of:
Normal finding
Anemia
Polycythemia
Overhydration
In anemia, the hematocrit value is usually:
Increased
Normal
Decreased
Unchanged
Hemoglobin = 10 g/dL and Hematocrit = 30% suggest:
Normal blood picture
Anemia
Polycythemia
Dehydration
Hemoglobin = 17 g/dL and Hematocrit = 51% indicate:
Anemia
Normal finding
Polycythemia
Acute blood loss
Which of the following is most likely in the case of:
Acute hemorrhage
Dehydration
Hemodilution
Hemodilution
Hemoglobin = 12 g/dL and Hematocrit = 36% in an adult female indicate:
Anemia
Normal result
Severe anemia
Dehydration
ESR mainly depends on:
RBC count only
Plasma protein
Platelet function
WBC count
Which plasma protein increases ESR the most?
Albumin
Fibrinogen
Hemoglobin
Globin
ESR is increased in which condition?
Polycythemia
Sickle cell anemia
Acute inflammation
Microcytosis
Which factor decreases ESR?
Pregnancy
Anemia
Infection
Which plasma protein has the greatest effect on increasing ESR?
Albumin
Hemoglobin
Fibrinogen
Transferrin
ESR increases mainly due to fibrinogen because it:
Increases RBC count
Enhances rouleaux formation
Decreases plasma viscosity
Increases hemoglobin concentration
Increased fibrinogen levels are commonly seen in:
Nephrotic syndrome
Acute inflammation
Liver failure
Severe anemia
Albumin affects ESR by:
Increasing rouleaux formation
Neutralizing negative charge on RBCs
Decreasing ESR
Increasing RBC aggregation
A decrease in albumin level will result in:
(a)
Which disease is associated with increased fibrinogen leading to high ESR?
Acute inflammation
Hemophilia
Thrombocytopenia
Iron overload
In chronic inflammatory diseases, ESR is elevated mainly due to:
Decreased RBC production
Increased fibrinogen
Increased hemoglobin level
Increased albumin level
Albumin normally reduces ESR because it:
Promotes RBC aggregation
Increases plasma density
Maintains negative charge on RBCs
Increases fibrinogen synthesis
Which condition shows decreased ESR due to high albumin level?
Glomerulonephritis syndrome
Polycythemia
Sickle cell anemia
Dehydration
Increased ESR in pericarditis is mainly due to:
Increased albumin
Increased fibrinogen
Decreased globulins
Increased RBC count
In liver disease, ESR may be increased because of:
Increased albumin synthesis
Decreased fibrinogen
Altered albumin–fibrinogen ratio
Increased RBC lifespan
Which protein change leads to the highest ESR?
High albumin with low fibrinogen
Low albumin with high fibrinogen
Normal albumin and fibrinogen
High albumin only
Which statement is CORRECT regarding ESR?
Albumin increases ESR more than fibrinogen
Fibrinogen is the main protein increasing ESR
ESR depends only on RBC count
ESR is unaffected by plasma proteins
ESR is decreased when the RBC count is:
Low
Normal
High
Variable
Polycythemia affects ESR by:
Increasing ESR
Decreasing ESR
Not affecting ESR
Falsely elevating ESR
Which RBC size is associated with increased ESR?
Microcytes
Normal-sized RBCs
Macrocytes
Sickle cells
Microcytic anemia affects ESR by:
Increasing ESR
Decreasing ESR
Not affecting ESR
Making ESR zero
Which RBC morphology leads to reduced ESR?
Rouleaux formation
Macrocytosis
Sickle cells
Normal biconcave shape
ESR is increased when RBCs:
Are small and numerous
Are large and fewer
Have abnormal shapes
Reduced rouleaux formation results in:
Increased ESR
Decreased ESR
No change in ESR
Falsely high ESR
In severe anemia, ESR is usually:
Decreased
Normal
Increased
Zero
Increased hematocrit affects ESR by:
Increasing ESR
Decreasing ESR
No effect on ESR
Doubling ESR
Which RBC feature promotes faster sedimentation?
Smaller size
Irregular shape
Larger size
Increased surface charge
ESR is lowest when RBCs are:
(a)
Which of the following describes the appearance of RBCs in a certain condition?
Few and large
Numerous and small
Normal in number
Large and aggregated
ESR increases when the test is performed at:
Low temperature
Normal room temperature
High temperature
Freezing temperature
High room temperature affects ESR by:
Slowing RBC sedimentation
Increasing plasma viscosity
Decreasing rouleaux formation
Enhancing RBC sedimentation
Low temperature causes ESR to:
Increase
Decrease
Remain unchanged
Become zero
The optimal temperature for accurate ESR testing is:
4°C
10°C
18–25°C
35–40°C
ESR performed in a cold room may give:
Falsely high results
Falsely low results
Correct results
Zero sedimentation
Which mechanism explains increased ESR at high temperature?
Increased RBC count
Reduced plasma proteins
Decreased plasma viscosity
Increased hemoglobin level
Temperature affects ESR mainly by altering:
RBC number
Plasma viscosity
Hemoglobin structure
Platelet function
ESR should be avoided in which condition to prevent false elevation?
Testing at room temperature
Testing in a hot environment
Proper vertical tube placement
Correct anticoagulant ratio
ESR value obtained at 35°C is likely to be:
Lower than normal
Normal
ESR should be measured within the recommended temperature range to:
Increase sensitivity
Avoid temperature-related false results
Speed up the test
Increase rouleaux formation
Which statement is CORRECT?
Low temperature increases ESR
High temperature decreases ESR
High temperature increases ESR
Temperature has no effect on ESR
Cold exposure during ESR testing leads to:
Faster sedimentation
Slower sedimentation
Increased rouleaux formation
Increased fibrinogen effect
ESR measures the rate at which ___ settle in a vertical column of blood:
WBCs
Platelets
RBCs
Plasma proteins
Which plasma protein increases ESR by promoting rouleaux formation?
Albumin
Fibrinogen
Globulin
Hemoglobin
Increased plasma albumin concentration causes ESR to:
Increase
Decrease
Stay the same
Fluctuate
Which of the following factors decreases ESR?
Increased fibrinogen
Anemia
Polycythemia
Inflammation
The reference temperature for ESR measurement is:
0–5ºC
10–15ºC
18–25ºC
30–40ºC
The normal range of MCV (Mean Corpuscular Volume) is:
70–80 μm³
80–100 μm³
100–120 μm³
60–70 μm³
In microcytic anemia, MCV is:
Increased
Decreased
Normal
Variable
