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Hemostatic Function Test

Total questions: 100

Worksheet time: 50mins

Name
Class
Date
1.

Thrombocytopenia is defined as a platelet count less than:

a)

50,000 /μL

b)

100,000 /μL

c)

150,000 /μL

d)

300,000 /μL

2.

Thrombocytopenia is defined as:

a)

Increase in platelet count above normal

b)

Decrease in platelet count below normal

c)

Deficiency of clotting factors

d)

Prolonged prothrombin time

3.

Thrombasthenia is:

a)

Decrease in platelet count

b)

Defect in platelet function

c)

Deficiency of clotting factors

d)

Increase in fibrinolysis

4.

Normal bleeding time is:

a)

30 seconds – 1 minute

b)

1 – 3 minutes

c)

2 – 7 minutes

d)

10 – 15 minutes

5.

Normal coagulation time is:

a)

1 – 3 minutes

b)

3 – 6 minutes

c)

3 – 10 minutes

6.

Hemophilia is:

a)

An acquired platelet disorder

b)

An inherited deficiency of coagulation factors (VIII or IX)

c)

A disorder of platelet adhesion

d)

Due to vitamin K deficiency

7.

Hemophilia occurs more frequently in:

a)

Males

b)

Females

c)

Both equally

d)

Newborns only

8.

Haemophilia type A is characterized by defect in factor:

a)

Factor VII

b)

Factor IX

c)

Factor VIII

d)

Factor X

9.

Haemophilia type B is characterized by defect in factor:

a)

Factor VIII

b)

Factor IX

c)

Factor VII

d)

Factor X

10.

Haemophilia type C is characterized by defect in factor:

(a)  

11.

Which clotting factor requires vitamin K for its synthesis?

a)

Factor I (Fibrinogen)

b)

Factor II (Prothrombin)

c)

Factor V

d)

Factor VIII

12.

Vitamin K deficiency can be caused by:

a)

Sterile intestine due to prolonged use of antibiotics

b)

Excessive vitamin C intake

c)

Iron deficiency

d)

Dehydration

13.

The most commonly used method for hemoglobin estimation in laboratories is:

a)

Sahli’s method

b)

Cyanmethemoglobin method

c)

Oxyhemoglobin method

d)

Acid hematin method

14.

Hemoglobin concentration is usually expressed in:

a)

mg/dL

b)

g/dL

c)

mmol/L

d)

%

15.

Which of the following is Factor X?

a)

Factor IX

b)

Factor XI

c)

Factor X

d)

Factor X

16.

Sahli’s method estimates hemoglobin based on the formation of:

a)

Cyanmethemoglobin

b)

Acid hematin

c)

Methemoglobin

d)

Carbaminohemoglobin

17.

Normal hemoglobin level in adult females is approximately:

a)

8–10 g/dL

b)

10–12 g/dL

c)

13–14 g/dL

d)

16–18 g/dL

18.

The main disadvantage of Sahli’s method is:

a)

It is time-consuming

b)

It is expensive

c)

It depends on visual color comparison

d)

It requires a spectrophotometer

19.

Hemoglobin estimation is important in the diagnosis of:

a)

Leukemia

b)

Thrombocytopenia

c)

Anemia

d)

Hemophilia

20.

Which sample is required for hemoglobin estimation?

a)

Serum

b)

Plasma

c)

Whole blood

21.

The normal hemoglobin level in adult males (by Sahli’s method) is:

a)

10–12 g/dL

b)

11–14 g/dL

c)

15–16 g/dL

d)

18–20 g/dL

22.

The normal hemoglobin level in adult females (by Sahli’s method) is:

a)

9–11 g/dL

b)

10–12 g/dL

c)

13–14 g/dL

d)

16–18 g/dL

23.

Which clotting factor requires vitamin K for its synthesis?

a)

Factor I (Fibrinogen)

b)

Factor II (Prothrombin)

c)

Factor V

d)

Factor VIII

24.

Vitamin K deficiency can be caused by:

a)

Sterile intestine due to prolonged use of antibiotics

b)

Excessive vitamin C intake

c)

Iron deficiency

d)

Dehydration

25.

The most commonly used method for hemoglobin estimation in laboratories is:

(a)  

26.

Which of the following is the most commonly used method for estimation of hemoglobin?

a)

Sahli’s method

b)

Cyanmethemoglobin method

c)

Oxyhemoglobin method

d)

Acid hematin method

27.

Hemoglobin concentration is usually expressed in:

a)

mg/dL

b)

g/dL

c)

mmol/L

d)

%

28.

Sahli’s method estimates hemoglobin based on the formation of:

a)

Cyanmethemoglobin

b)

Acid hematin

c)

Methemoglobin

d)

Carbanimohemoglobin

29.

Normal hemoglobin level in adult females is approximately:

a)

8–10 g/dL

b)

10–12 g/dL

c)

13–14 g/dL

d)

16–18 g/dL

30.

The main disadvantage of Sahli’s method is:

a)

It is time-consuming

b)

It is expensive

c)

It depends on visual color comparison

d)

It requires a spectrophotometer

31.

Hemoglobin estimation is important in the diagnosis of:

a)

Leukemia

b)

Thrombocytopenia

c)

Anemia

d)

Hemophilia

32.

Which sample is required for hemoglobin estimation?

a)

Serum

b)

Plasma

c)

Whole blood

d)

Urine

33.

The normal hemoglobin level in adult males (by Sahli’s method) is:

a)

10–12 g/dL

b)

11–14 g/dL

c)

15–16 g/dL

d)

18–20 g/dL

34.

The normal hemoglobin level in adult females (by Sahli’s method) is:

a)

9–11 g/dL

b)

10–12 g/dL

c)

13–14 g/dL

d)

16–18 g/dL

35.

Which of the following hemoglobin values is considered normal for a child?

a)

6–8 g/dL

b)

8–10 g/dL

c)

19 g/dL

d)

14–16 g/dL

36.

The normal hematocrit value in adult males is approximately:

a)

30–35%

b)

36–40%

c)

47%

d)

55–65%

37.

The normal hematocrit value in adult females is approximately:

a)

25–30%

b)

30–35%

c)

42%

d)

48–55%

38.

A hematocrit value of 28% is most suggestive of:

a)

Polycythemia

b)

Dehydration

c)

Anemia

d)

Normal finding

39.

Hematocrit is defined as:

a)

Total hemoglobin concentration in blood

b)

Percentage of red blood cells in whole blood

c)

Number of RBCs per microliter

d)

Volume of plasma only

40.

In anemia, both hemoglobin level and hematocrit are usually:

a)

Increased

b)

Normal

c)

Decreased

41.

An adult male with a hemoglobin level of 18 g/dL is most likely to have:

a)

Iron deficiency anemia

b)

Normal finding

c)

Polycythemia

d)

Acute blood loss

42.

A hemoglobin level of 6 g/dL is classified as:

a)

Normal

b)

Mild anemia

c)

Moderate anemia

d)

Severe anemia

43.

A hemoglobin value within normal limits usually suggests:

a)

Normal oxygen-carrying capacity

b)

Increased plasma volume

c)

Thrombocytopenia

d)

Clotting factor deficiency

44.

A hematocrit value of 32% in an adult male indicates:

a)

Normal hematocrit

b)

Anemia

c)

Polycythemia

d)

Dehydration

45.

An increased hematocrit value is commonly seen in:

a)

Iron deficiency anemia

b)

Polycythemia

c)

Acute blood loss

d)

Unrelated

46.

A decreased hematocrit value is commonly seen in:

a)

Iron deficiency anemia

b)

Polycythemia

c)

Decreased

d)

Unrelated

47.

A hematocrit value of 55% is most suggestive of:

a)

Normal finding

b)

Anemia

c)

Polycythemia

d)

Overhydration

48.

In anemia, the hematocrit value is usually:

a)

Increased

b)

Normal

c)

Decreased

d)

Unchanged

49.

Hemoglobin = 10 g/dL and Hematocrit = 30% suggest:

a)

Normal blood picture

b)

Anemia

c)

Polycythemia

d)

Dehydration

50.

Hemoglobin = 17 g/dL and Hematocrit = 51% indicate:

a)

Anemia

b)

Normal finding

c)

Polycythemia

d)

Acute blood loss

51.

Which of the following is most likely in the case of:

a)

Acute hemorrhage

b)

Dehydration

c)

Hemodilution

d)

Hemodilution

52.

Hemoglobin = 12 g/dL and Hematocrit = 36% in an adult female indicate:

a)

Anemia

b)

Normal result

c)

Severe anemia

d)

Dehydration

53.

ESR mainly depends on:

a)

RBC count only

b)

Plasma protein

c)

Platelet function

d)

WBC count

54.

Which plasma protein increases ESR the most?

a)

Albumin

b)

Fibrinogen

c)

Hemoglobin

d)

Globin

55.

ESR is increased in which condition?

a)

Polycythemia

b)

Sickle cell anemia

c)

Acute inflammation

d)

Microcytosis

56.

Which factor decreases ESR?

a)

Pregnancy

b)

Anemia

c)

Infection

57.

Which plasma protein has the greatest effect on increasing ESR?

a)

Albumin

b)

Hemoglobin

c)

Fibrinogen

d)

Transferrin

58.

ESR increases mainly due to fibrinogen because it:

a)

Increases RBC count

b)

Enhances rouleaux formation

c)

Decreases plasma viscosity

d)

Increases hemoglobin concentration

59.

Increased fibrinogen levels are commonly seen in:

a)

Nephrotic syndrome

b)

Acute inflammation

c)

Liver failure

d)

Severe anemia

60.

Albumin affects ESR by:

a)

Increasing rouleaux formation

b)

Neutralizing negative charge on RBCs

c)

Decreasing ESR

d)

Increasing RBC aggregation

61.

A decrease in albumin level will result in:

(a)  

62.

Which disease is associated with increased fibrinogen leading to high ESR?

a)

Acute inflammation

b)

Hemophilia

c)

Thrombocytopenia

d)

Iron overload

63.

In chronic inflammatory diseases, ESR is elevated mainly due to:

a)

Decreased RBC production

b)

Increased fibrinogen

c)

Increased hemoglobin level

d)

Increased albumin level

64.

Albumin normally reduces ESR because it:

a)

Promotes RBC aggregation

b)

Increases plasma density

c)

Maintains negative charge on RBCs

d)

Increases fibrinogen synthesis

65.

Which condition shows decreased ESR due to high albumin level?

a)

Glomerulonephritis syndrome

b)

Polycythemia

c)

Sickle cell anemia

d)

Dehydration

66.

Increased ESR in pericarditis is mainly due to:

a)

Increased albumin

b)

Increased fibrinogen

c)

Decreased globulins

d)

Increased RBC count

67.

In liver disease, ESR may be increased because of:

a)

Increased albumin synthesis

b)

Decreased fibrinogen

c)

Altered albumin–fibrinogen ratio

d)

Increased RBC lifespan

68.

Which protein change leads to the highest ESR?

a)

High albumin with low fibrinogen

b)

Low albumin with high fibrinogen

c)

Normal albumin and fibrinogen

d)

High albumin only

69.

Which statement is CORRECT regarding ESR?

a)

Albumin increases ESR more than fibrinogen

b)

Fibrinogen is the main protein increasing ESR

c)

ESR depends only on RBC count

d)

ESR is unaffected by plasma proteins

70.

ESR is decreased when the RBC count is:

a)

Low

b)

Normal

c)

High

d)

Variable

71.

Polycythemia affects ESR by:

a)

Increasing ESR

b)

Decreasing ESR

c)

Not affecting ESR

d)

Falsely elevating ESR

72.

Which RBC size is associated with increased ESR?

a)

Microcytes

b)

Normal-sized RBCs

c)

Macrocytes

d)

Sickle cells

73.

Microcytic anemia affects ESR by:

a)

Increasing ESR

b)

Decreasing ESR

c)

Not affecting ESR

d)

Making ESR zero

74.

Which RBC morphology leads to reduced ESR?

a)

Rouleaux formation

b)

Macrocytosis

c)

Sickle cells

d)

Normal biconcave shape

75.

ESR is increased when RBCs:

a)

Are small and numerous

b)

Are large and fewer

c)

Have abnormal shapes

76.

Reduced rouleaux formation results in:

a)

Increased ESR

b)

Decreased ESR

c)

No change in ESR

d)

Falsely high ESR

77.

In severe anemia, ESR is usually:

a)

Decreased

b)

Normal

c)

Increased

d)

Zero

78.

Increased hematocrit affects ESR by:

a)

Increasing ESR

b)

Decreasing ESR

c)

No effect on ESR

d)

Doubling ESR

79.

Which RBC feature promotes faster sedimentation?

a)

Smaller size

b)

Irregular shape

c)

Larger size

d)

Increased surface charge

80.

ESR is lowest when RBCs are:

(a)  

81.

Which of the following describes the appearance of RBCs in a certain condition?

a)

Few and large

b)

Numerous and small

c)

Normal in number

d)

Large and aggregated

82.

ESR increases when the test is performed at:

a)

Low temperature

b)

Normal room temperature

c)

High temperature

d)

Freezing temperature

83.

High room temperature affects ESR by:

a)

Slowing RBC sedimentation

b)

Increasing plasma viscosity

c)

Decreasing rouleaux formation

d)

Enhancing RBC sedimentation

84.

Low temperature causes ESR to:

a)

Increase

b)

Decrease

c)

Remain unchanged

d)

Become zero

85.

The optimal temperature for accurate ESR testing is:

a)

4°C

b)

10°C

c)

18–25°C

d)

35–40°C

86.

ESR performed in a cold room may give:

a)

Falsely high results

b)

Falsely low results

c)

Correct results

d)

Zero sedimentation

87.

Which mechanism explains increased ESR at high temperature?

a)

Increased RBC count

b)

Reduced plasma proteins

c)

Decreased plasma viscosity

d)

Increased hemoglobin level

88.

Temperature affects ESR mainly by altering:

a)

RBC number

b)

Plasma viscosity

c)

Hemoglobin structure

d)

Platelet function

89.

ESR should be avoided in which condition to prevent false elevation?

a)

Testing at room temperature

b)

Testing in a hot environment

c)

Proper vertical tube placement

d)

Correct anticoagulant ratio

90.

ESR value obtained at 35°C is likely to be:

a)

Lower than normal

b)

Normal

91.

ESR should be measured within the recommended temperature range to:

a)

Increase sensitivity

b)

Avoid temperature-related false results

c)

Speed up the test

d)

Increase rouleaux formation

92.

Which statement is CORRECT?

a)

Low temperature increases ESR

b)

High temperature decreases ESR

c)

High temperature increases ESR

d)

Temperature has no effect on ESR

93.

Cold exposure during ESR testing leads to:

a)

Faster sedimentation

b)

Slower sedimentation

c)

Increased rouleaux formation

d)

Increased fibrinogen effect

94.

ESR measures the rate at which ___ settle in a vertical column of blood:

a)

WBCs

b)

Platelets

c)

RBCs

d)

Plasma proteins

95.

Which plasma protein increases ESR by promoting rouleaux formation?

a)

Albumin

b)

Fibrinogen

c)

Globulin

d)

Hemoglobin

96.

Increased plasma albumin concentration causes ESR to:

a)

Increase

b)

Decrease

c)

Stay the same

d)

Fluctuate

97.

Which of the following factors decreases ESR?

a)

Increased fibrinogen

b)

Anemia

c)

Polycythemia

d)

Inflammation

98.

The reference temperature for ESR measurement is:

a)

0–5ºC

b)

10–15ºC

c)

18–25ºC

d)

30–40ºC

99.

The normal range of MCV (Mean Corpuscular Volume) is:

a)

70–80 μm³

b)

80–100 μm³

c)

100–120 μm³

d)

60–70 μm³

100.

In microcytic anemia, MCV is:

a)

Increased

b)

Decreased

c)

Normal

d)

Variable