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WorksheetsAFTER LECTURE QUIZ
Total questions: 10
Worksheet time: 5mins
Dapagliflozin belongs to which antidiabetic drug class?
Biguanides
DPP-4 inhibitors
SGLT2 inhibitors
GLP-1 receptor agonists
What is the primary mechanism of action of dapagliflozin?
Increasing insulin secretion from pancreatic beta cells
Decreasing hepatic glucose production
Inhibiting glucose absorption in the intestines
Inhibiting renal glucose reabsorption, leading to glucose excretion
Dapagliflozin is mainly indicated for patients with type 2 diabetes who also have:
Asthma
Peptic ulcer disease
Heart failure and/or chronic kidney disease
Thyroid disorders
Which of the following is a common adverse effect of dapagliflozin?
Severe constipation
Urinary tract infection
Bradycardia
Visual disturbances
Which condition is a contraindication to dapagliflozin use?
Type 2 diabetes
Chronic kidney disease
Type 1 diabetes
Obesity
What is the recommended starting dose of dapagliflozin for glycemic control?
2.5 mg once daily
5 mg once daily
20 mg once daily
25 mg once daily
Which among the following drugs have the highest volume of distribution?
Ertugliflozin
Empagliflozin
Canagliflozin
Dapagliflozin
Which of the following benefits is associated with dapagliflozin therapy?
Increased LDL cholesterol only
Weight gain and fluid retention
Cardioprotection and nephroprotection
High risk of hypoglycemia
Which drug interaction may increase the risk of volume depletion when used with dapagliflozin?
Antacids
Diuretics
Proton pump inhibitors
H2 blockers
Compared with DPP-4 inhibitors such as sitagliptin, dapagliflozin is more notable for its:
Gastrointestinal tolerability
Neutral effect on body weight
Significant cardiorenal benefits
Shorter duration of action
