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Vaccines and Immunology Quiz

Total questions: 20

Worksheet time: 10mins

Name
Class
Date
1.

Live vaccines are characterized by

a)

No replication in host

b)

Require multiple boosters

c)

Replication in host

d)

Only humoral immunity

2.

Killed vaccines differ from live vaccines because they

a)

Can revert to virulence

b)

Induce weaker immunity

c)

Are contraindicated in pregnancy

d)

Require cold chain less

3.

Example of live attenuated vaccine is

a)

IPV

b)

Inactivated influenza

c)

BCG

d)

Tetanus toxoid

4.

Example of killed/inactivated vaccine is

a)

MMR

b)

OPV

c)

IPV

d)

BCG

5.

Live vaccines are contraindicated in

a)

Healthy adults

b)

Children

c)

Immunocompromised patients

d)

Non-pregnant women

6.

Universal Immunization Programme (UIP) in India was launched in

a)

1978

b)

1985

c)

1992

d)

2000

7.

BCG vaccine in National Immunization Schedule is given at

a)

Birth

b)

6 weeks

c)

10 weeks

d)

14 weeks

8.

OPV zero dose is given at

a)

Birth

b)

6 weeks

c)

10 weeks

d)

14 weeks

9.

Pentavalent vaccine protects against

a)

DPT only

b)

DPT + Hep B + Hib

c)

DPT + Polio + Measles

d)

BCG + DPT

10.

Measles/MR vaccine is given first at age of

a)

6 weeks

b)

9 months

c)

12 months

d)

5 years

11.

Vitamin A first dose is given at

a)

6 weeks

b)

9 months

c)

12 months

d)

18 months

12.

Anaphylaxis is a type of hypersensitivity

a)

Type II

b)

Type III

c)

Type I

d)

Type IV

13.

Antibody involved in anaphylaxis is

a)

IgG

b)

IgM

c)

IgA

d)

IgE

14.

Cells primarily responsible for anaphylaxis

a)

Neutrophils

b)

Macrophages

c)

Mast cells and basophils

d)

T lymphocytes

15.

Immediate mediator released in anaphylaxis

a)

Prostaglandins

b)

Leukotrienes

c)

Histamine

d)

Bradykinin

16.

Drug of choice in anaphylaxis

a)

Antihistamine

b)

Hydrocortisone

c)

Adrenaline

d)

Noradrenaline

17.

Acute phase reactant proteins are synthesized mainly by

a)

Spleen

b)

Bone marrow

c)

Liver

d)

Lymph nodes

18.

C-reactive protein (CRP) is increased in

a)

Only chronic inflammation

b)

Only acute inflammation

c)

Both acute and chronic inflammation

d)

Allergic reactions only

19.

CRP is mainly induced by cytokine

a)

IL-1

b)

IL-6

c)

IL-10

d)

TNF-β

20.

CRP functions include all EXCEPT

a)

Opsonization

b)

Complement activation

c)

Anti-inflammatory action only

d)

Marker of inflammation