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benign and malignant of ovaries

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

Which ovarian malignancy is most strongly associated with BRCA mutation and often shows psammoma bodies on histology?

a)

Mucinous carcinoma

b)

Dysgerminoma

c)

High-grade serous carcinoma

d)

Granulosa cell tumour

2.

Which benign ovarian tumour commonly contains hair and teeth due to differentiation of all three germ layers?

a)

Serous cystadenoma

b)

Endometrioma

c)

Dermoid cyst (mature teratoma)

d)

Follicular cyst

3.

Which of the following is a risk factor for ovarian cancer?

a)

Multiparity

b)

Late menopause

c)

Use of combined oral contraceptive pills

d)

Early first pregnancy

4.

High-grade serous ovarian carcinoma is believed to originate primarily from which site according to the fallopian tube theory?

a)

Ovarian cortex

b)

Fimbrial end of fallopian tube

c)

Endometrium

d)

Peritoneum

5.

A woman presents with sudden severe lower abdominal pain and vomiting; ultrasound shows an ovarian cyst. What is the most likely complication?

a)

Endometriosis

b)

Ovarian torsion

c)

PID

d)

Ruptured ectopic pregnancy

6.

Which investigation is most accurate for characterising an ovarian cyst?

a)

CT abdomen

b)

MRI pelvis

c)

Transvaginal ultrasound

d)

Abdominal X-ray

7.

Which surgery is part of standard staging operation for ovarian cancer?

a)

Cystectomy only

b)

Total abdominal hysterectomy with bilateral salpingo-oophorectomy and omentectomy

c)

Myomectomy

d)

Appendectomy only

8.

Which tumour marker is most useful in follow-up of granulosa cell tumours?

a)

CA-125

b)

hCG

c)

Inhibin

d)

AFP

9.

Which of the following clinical features is most suggestive of ovarian malignancy rather than a benign cyst?

a)

Unilateral small cyst

b)

Mobile, smooth mass

c)

Ascites with fixed irregular mass

d)

Mild lower abdominal discomfort

10.

Which combination is commonly used as first-line chemotherapy in epithelial ovarian cancer?

a)

Methotrexate + 5-FU

b)

Carboplatin + Paclitaxel

c)

Doxorubicin + Cyclophosphamide

d)

Cisplatin + Vincristine