Font size
WorksheetsAsthma Management (GINA) – Worksheet Questions
Total questions: 13
Worksheet time: 7mins
Which statements regarding preferred reliever therapy according to GINA are CORRECT?
As-needed low-dose ICS–formoterol is preferred in adults and adolescents at all treatment steps
As-needed ICS–formoterol is universally preferred in children 6–11 years
Formoterol is suitable as a reliever due to its rapid onset of action
SABA-only reliever therapy increases risk of severe exacerbations
Salmeterol may be used as a reliever if combined with ICS
Why is montelukast considered inferior to ICS as monotherapy in asthma?
Poor oral bioavailability
Lack of bronchodilator effect
Limited anti-inflammatory spectrum
Short half-life
Which pharmacodynamic property makes formoterol suitable for both maintenance and reliever therapy in asthma?
High intrinsic activity with slow onset
Partial agonism at β2-receptors
Rapid onset with long receptor residence time
Non-selective β-agonism
Increasing the dose of inhaled corticosteroids during an acute asthma exacerbation is preferred over initiating systemic corticosteroids.
True
False
Leukotriene receptor antagonists (e.g., montelukast) are less effective than inhaled corticosteroids in preventing asthma exacerbations.
True
False
In GINA Step 2 treatment, what is the preferred dosing strategy for adults and adolescents?
Daily SABA plus as-needed ICS
As-needed low-dose ICS–formoterol
Daily high-dose ICS
Daily LABA monotherapy
A patient using budesonide–formoterol as maintenance and reliever therapy (MART) exceeds the recommended daily inhalations. What is the primary concern?
Loss of bronchodilator efficacy
Increased risk of β2-agonist adverse effects
Acute adrenal suppression
Reduced inhaled corticosteroid absorption
According to GINA, which of the following represents a low daily dose of inhaled budesonide in children aged 6–11 years, compared with adults?
Children: 100–200 mcg/day; Adults: 200–400 mcg/day
Children: 200–400 mcg/day; Adults: 400–800 mcg/day
Children: 50–100 mcg/day; Adults: 100–200 mcg/day
Children and adults have the same low-dose range
Which of the following are appropriate step-up options for a patient uncontrolled on low-dose ICS–LABA? Select ALL that apply.
Increase to medium-dose ICS–LABA
Add tiotropium (LAMA)
Switch to LABA monotherapy
Assess adherence and inhaler technique before stepping up
Add a leukotriene receptor antagonist
Which conditions must be met before stepping down asthma treatment? Select ALL that apply.
Good control maintained for ≥3 months
No recent exacerbations
Patient has good inhaler technique and adherence
Gradual dose reduction rather than abrupt stopping
According to GINA, which statements regarding reliever therapy and Step 1–2 treatment in adults/adolescents and children aged 6–11 years are CORRECT? Select ALL that apply.
In adults and adolescents, as-needed low-dose ICS–formoterol is preferred over SABA because it reduces severe exacerbations even in patients with infrequent symptoms.
In children aged 6–11 years, taking low-dose ICS whenever SABA is taken is preferred to daily ICS at Step 1.
SABA-only therapy remains acceptable in adolescents who have normal lung function and no history of exacerbations.
As-needed ICS–formoterol is not recommended as a reliever option in children aged 6–11 years at Steps 1–2.
Which statements regarding controller escalation and Maintenance-and-Reliever Therapy (MART) are CORRECT according to GINA? Select ALL that apply.
MART is preferred at Step 3 for adults and adolescents using low-dose ICS–formoterol.
Only ICS–LABA combinations containing formoterol are suitable for MART.
MART may be considered in children aged 6–11 years at Step 4 under specialist supervision.
Which of the following represents a high daily dose of fluticasone propionate in adults?
200 mcg/day
400 mcg/day
500 mcg/day
100 mcg/day
