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WorksheetsOrion 60-76
Total questions: 129
Worksheet time: 1hrs 5mins
Acute heart failure patient with shortness of breath and peripheral edema: which Forrester classification applies?
dry and cold
wet and cold
dry and warm
wet and warm stage
Which of the following is a vasopressor that is given in a fixed dose without titration for patients with septic shock?
dopamine
vasopressin
epinephrine
norepinephrine
Septic shock patient unresponsive to fluid: what will you give?
vasopressin
dopamine
norepinephrine
Diagnosis of STEMI: which finding best supports the diagnosis?
elevated ST segment with increased troponin
elevated ST segment with increased BNP
elevated ST segment with increased CK
A patient has allergic rhinitis and was prescribed pseudoephedrine. You find a history of hypertension. What should you do?
Do not dispense the prescription
Use pseudoephedrine with caution if hypertension is controlled
Use pseudoephedrine with caution if hypertension is not controlled
A patient taking lisinopril and many other medicines (HTN, DM, dyslipidemia) is prescribed prazosin 1 mg for BPH. He develops orthostatic hypotension. What is the best action?
Discontinue lisinopril
Discontinue prazosin
Discontinue prazosin and give alfazosin
Start finasteride
What resting heart rate target should be used for a patient taking metoprolol who has atrial fibrillation?
60 beat/min
90 beat/min
120 beat/min
200 beat/min
What is the main advantage of losartan over lisinopril?
less induction of cough
higher oral bioavailability
Duration of treatment for aspirin in a cardiovascular patient: choose the best option.
1 year
2 years
3 years
5 years
Blood pressure in a neonate compared with an adult is
the same as adult
higher than adult
lower than adult
A patient with angina and MI who takes an ACE inhibitor and many other medicines presents with high blood pressure. What should be given?
spironolactone
carvedilol
diltiazem
ARBs
Which of the following can cause digoxin toxicity?
hypomagnesemia
hypercalcemia
hypophosphate
A patient with hypotension and a high heart rate: what should be given?
hypertonic NaCl
Ringer’s lactate RL
albumin
Female patient with food poisoning presented with elevated troponin and NSTEMI. What is the appropriate management?
aspirin 81 mg + ticagrelor
aspirin 325 mg + ticagrelor
aspirin 81 mg + prasugrel
aspirin 325 mg + prasugrel
Patient on furosemide 40 mg IV: change to an oral dose. (Conversion: 2 mg PO = 1 mg IV)
20 mg PO
40 mg PO
80 mg PO
120 mg PO
Which of the following is a loop diuretic?
furosemide
acetazolamide
spironolactone
hydrochlorothiazide
Which of the following is a potential side effect of chlorothiazide?
hyperkalemia
hypocalcemia
hypouricemia
hypokalemia
A man is started on a new medication to control elevated blood pressure. After one month he notes his breasts have become enlarged and tender. Which medication was most likely prescribed?
acetazolamide
chlorthalidone
spironolactone
hydrochlorothiazide
Which of the following diuretics is an aldosterone antagonist?
furosemide
acetazolamide
spironolactone
hydrochlorothiazide
Which loop diuretic is safe to use in a patient with a sulfa allergy?
ethacrynic acid
furosemide
bumetanide
torsemide
Which of the following is a loop diuretic?
furosemide
acetazolamide
spironolactone
hydrochlorothiazide
Which of the following medications is an osmotic diuretic?
mannitol
furosemide
spironolactone
hydrochlorothiazide
A 75-year-old man with NYHA IV heart failure is started on furosemide 120 mg intravenous infusion to improve pulmonary edema. What is the recommended duration for the infusion?
10 minutes
20 minutes
30 minutes
40 minutes
A patient taking some drugs develops hyperkalemia. Which of the following drugs can cause this?
theophylline
spironolactone
gentamicin
Which pharmacoeconomic study is the simplest because outcomes are assumed equivalent and only intervention costs are compared?
cost-utility analysis
cost-benefit analysis
cost-minimization analysis
Which of the following pharmacoeconomic studies is the simplest to conduct?
cost-utility analysis
cost-benefit analysis
cost-minimization analysis
cost-effectiveness analysis
From a pharmacoeconomic perspective, what type of cost is traveling from Jeddah to Riyadh to obtain health care?
indirect
intangible
direct nonmedical
non-direct medical
What kind of outcomes can be determined by cost-minimization?
monetary units (e.g., dollars)
quality-adjusted life-years (QALYS)
natural units (e.g., life-years saved)
comparing the cost of two identical products (e.g., generic brand)
Which statement best describes the incremental cost-effectiveness ratio?
the cost per extra benefit of a new strategy, independent
the extra cost to obtain an extra benefit when switching from one alternative to another
the cost per quality-adjusted life year gained
a summary measurement of efficiency
A P&T committee requests monetary (dollar) valuation for including a product in the hospital formulary. Which pharmacoeconomics tool should the pharmacy use?
cost-utility analysis
cost-benefit analysis
cost-minimization analysis
cost-effectiveness analysis
In pharmacoeconomics and outcomes research, QALYs are used as utilities. QALY is the quality-adjusted life year. Which of the following is an interpretation of an individual with perfect health?
death
coma
illness
perfect health
Case about one using two drugs of cancer, one with less side effect to choose. What is cost?
Cost-Effectiveness
Cost-Minimization
Case Study
Cohort Study
Case about one using two drugs of cancer, one with less side effect to choose. What is cost?
Cost-Effectiveness
Cost-Minimization
Case Study
Cohort Study
Question How to prepare a budget for the new year?
Close stock + open stock + seller products
Open stock - close stock + Seller product
Open stock + Seller Product - close stock
Which of the following perspectives incorporates all the costs and regardless of who incurs or obtains them?
Patient
Hospital
Societal
Ministry of Health
A 34-year-old woman who is still experiencing symptoms of hyperthyroidism despite treatment with carbimazole. Which medication can be added to provide additional symptomatic relief?
Lisinopril
Ibuprofen
Propranolol
Prednisolone
Which of following play a role in calcium homeostasis?
1,25-dihydroxycholecalciferol and calcitonin
1,25-dihydroxycholecalciferol and insulin
Parathyroid hormone and glucagon
Insulin and lipase
Which of the following is the timeline when symptoms start to occur in type 1 diabetes mellitus?
as early when destruction of the islets of Langerhans of the pancreas is starting
when 50% of the islets of Langerhans of the pancreas are destroyed
when 70% of the islets of Langerhans of the pancreas are destroyed
when destruction of the islets of Langerhans of the pancreas is complete
Which of the following conditions use "the plate method" as lifestyle modification?
asthma
dyslipidemia
hypertension
diabetes mellitus
Which of the following conditions use the plate method as a lifestyle modification?
hypertension
thyroid disorder
diabetes mellitus
myocardial infraction
Which of the following describe glucose uptake and usage by brain cells as compared to other tissues of the body?
Brain cell can uptake and use glucose only in the presence
Brain cells can uptake and use glucose without being stimuli insulin
Brain cells can uptake and use glucose when glucose is about 100 mg/dL in the blood
Brain cells can uptake and use glucose when the insulin is at high level in the body
Which of the following group of drugs can prevent the progression of micro-albuminuria to macro-albuminuria in patients with diabetic mellitus?
Angiotensin-converting enzyme inhibitors
B-blockers
Diuretics
Digitalis
A 65-year-old man was diagnosed with type 2 diabetes five years ago, maintained on metformin. Which of the following need to be monitored?
Vitamin C level
Vitamin D level
Vitamin B1 level
Vitamin B12 level
Which of the following insulins has the longest duration of action?
Aspart
Detemir
Glargine
Degludec (42 hr)
A 33-year-old woman who presents with complaints of fatigue and weight gain. She is planning to become pregnant. She reported that she starts taking multivitamin and supplements her current medication of levothyroxine 100 mcg daily. Based on the lab results provided, which of the following is the dosage recommendation in mcg to take daily for thyroid medication when she became pregnant?
levothyroxine-50
levothyroxine-75
levothyroxine-100
levothyroxine-125
A patient with DM type 2, with uncontrolled high blood glucose for years. The patient complains of burning and stabbing pain in his extremities started for years. Which of the following types of pain is this patient experiencing?
Acute pain
Costochondritis
Neuropathic pain
inflammatory pain
A 50-year-old Saudi woman with hypertension and dyslipidemia presents today to her follow up visit with family medicine clinic. Her sister has type 1 diabetes mellitus. No alcohol or cigarette use is reported. She is physically active for 2 minutes a week. Weight 51 kg and height 160 cm. Which of the following is a risk factor for developing diabetes type 2 in this patient?
Age
BMI
Gender
Family History
Which of the following is the mechanism of action of liraglutide?
Dipeptidyl peptidase 4 inhibitor
Glucagon like peptide-1 receptor agonist
Sodium/glucose co-transporter 2 inhibitor
Activate peroxisome proliferator-activated receptor
Which of the following describes the mechanism of action of sitagliptin?
Inhibit alpha glucosidase enzyme
Inhibit dipeptidyl peptidase 4 enzyme
Activate peroxisome proliferator-activated receptors
Closes ATP-dependent potassium channels in the B-cells
Which anti-hyperthyroidism drug could cause agranulocytosis?
Xylocaine
Metoprolol
Sodium Iodide
Propylthiouracil
Which anti-hyperthyroidism drug could cause agranulocytosis?
Xylocaine
Metoprolol
Sodium Iodide
Propylthiouracil
Preventing diabetic foot ulcers?
Proper footwear
Daily foot inspection
monitor blood sugar level
Weight losses
DM patient on insulin but he is not taking his dose, his HbA1c is 12%, he refuses taking insulin right dose because of weight gain. What do you do as a pharmacist?
Refer to physician to decrease his insulin dose
decrease his doses
try to change his beliefs on insulin
tell him it's ok to not take his dose
Which of the following to be used with caution in renal failure?
Glipizide
Rosiglitazone
Sitagliptin
Linagliptin
One of hyperthyroidism
Weight gain
Sensitivity to cold
Nervousness
Depression
Medication given for hyperthyroidism causes permanent decline in thyroid hormones?
PTU
methimazole
RAI radio active iodine
To decrease side effects of metformin on GI?
Divide doses
take dose after two hours of eating
take it with antihistamine
take it with PPI
Longest duration of action?
Degludec
Glargine
Aspart
NPH
Case about a diabetic patient type 2, he takes metformin but his blood sugar is so high and uncontrolled and Hb1Ac was very high. What to take?
insulin glargine + insulin asprt
insulin glargine + glyburide
Main features of Graves' disease include:
diffuse goiter
thyroid eye disease
pretibial myxoedema
thyroid acropathy
DM 1 patient, give what?
Sulfonylurea
GLP1 (liraglutide)
DDP
Pioglitazone
Which pattern of thyroid function tests is most consistent with hyperthyroidism?
Elevated TSH, increased T4
Increased T4, elevated TSH
Elevated TSH, decreased T4
Elevated T4, decreased TSH
A 48-year-old woman with diabetes on metformin 850 mg twice daily has hemoglobinated sugar increased by 1% compared with her last result. What will you advise?
Increase metformin dose
Decrease metformin dose
Do nothing
Shift to another type insulin
Which of the following is not a secondary cause of dyslipidemia?
Hypothyroidism
Hyperthyroidism
Diabetes
Protease inhibit
Why is propylthiouracil (PTU) the antithyroid therapy of choice in pregnant patients with Graves disease?
It is less hepatotoxic than methimazole (MMI)
It may be less teratogenic than MMI
It has less risk of causing fetal hypothyroidism than MMI
It causes less agranulocytosis in these patients than MMI
Untreated hyperthyroidism in the elderly can result in
Mania
Atrial fibrillation
Deafness
Hirsutism
A patient with hypertension, heart failure, and diabetes: what is the first line after metformin?
Pioglitazone
Gliclazide
Empagliflozin
Insulin
A patient on TPN and nothing by oral (NOP) with A1C blood glucose of 11: Which drug should be added?
Gliclazide
NPH insulin
Glargine
Regular insulin
Best antipsychotic drug for diabetic patient
Clozapine
Aripiprazole
Quetiapine
Which of the following lab results supports a diagnosis of primary hyperthyroidism?
Low TSH and a low free T4
Low TSH and elevated free T4
Elevated TSH and low free T4
Elevated TSH and elevated T4
A prescription shows Xalatan drops 1 drop o.n.m., 1 bottle. Which of the following is the most likely condition?
Cataract
Glaucoma
Blepharitis
Conjunctivitis
A prescription shows Xalatan drops 1 drop o.n.m., 1 bottle. Which of the following is the most likely condition?
Cataract
Glaucoma
Blepharitis
Conjunctivitis
A 62-year-old woman with open-angle glaucoma accidentally applies excessive pilocarpine to her eyes. Which of the following is the most likely expected result?
Mydriasis
Dilation of blood vessels
Bronchial smooth muscle dilation
Decreased gastrointestinal motility
Which of the following is the most practical method for sterilizing ophthalmic solution?
Autoclave for 15 minutes
Autoclave for 30 minutes
Membrane filtration through 0.2-μm filter
Membrane filtration through 5-μm filter
Which of the following prostaglandin analogs is used specific for the treatment of glaucoma?
Alprostadil
Latanoprost
Carboprost
Dinoprostone
Epoprostenol
Xalatan drops used for
Glaucoma
Fungal infection
Bacterial infection
Viral infection
Approximately 415 million people have been diagnosed with diabetes. Which of the following terms is referred to in the mentioned statement?
Endemic
Epidemic
Incidence
Prevalence
What is the Latin abbreviation for after meals?
A.C.
A.A.
P.C.
I.C.
What is the estimated amount of plasma in a 70-kg male (50–55 ml/kg)?
3.5 liter
1.1 liter
35 liter
11 liter
Which of the following is the abbreviation for drug to be taken by mouth?
P.O
p.R
PRN
U.D
An adult female patient with weight 80 kg and 160 cm height: How do you categorize this patient’s weight based on the classification shown (BMI: <18.5 under weight; 18.5–24.9 normal; 25–29.9 over weight; >30 obese)?
Obese
Normal
Overweight
Underweight
Which of the following describes the best patient instruction regarding the proper way to dispose of needles?
Discard the needle in garbage
Return the needles to their original package
Discard the needles in a rigid and resistant container
If the needles are for personal use, you can use them two times to reduce environment contamination
Which of the following studies could establish the drug shelf-life?
Bioavailability
Bioequivalence
Stability studies
Pharmacodynamic
What is the age range of a neonate?
Birth to one week
Birth to one month
One month to six months
One month to twelve months
Which of the following statements best represents the intravenous (IV) medications in hospital facilities?
IV drugs transmit the highest risk of infection
IV drugs are associated with lowest risk of undesirable side effects
IV solutions must be hypotonic to ensure compatibility with blood osmolality
IV solutions must be hypertonic to ensure compatibility with blood osmolality
Which of the following type of water should be used for reconstitution of parenteral preparations?
Sterile water
Distilled water
Sterile water for injection
Bacteriostatic water for injection
Which of the following solutions is required for the reconstitution of parenteral formulations?
USP standard sterile water
USP standard purified water
USP standard highly purified water
USP standard sterile water for injection
Which of the following food supplement is rich in omega-3 fatty acids?
Fish oil
Palm oil
Peanut oil
Coconut oil
Which of the following is an alternative name for vitamin B6?
Biotin
Thiamine
Pyridoxine
Cyanocobalamin
Which of the following routes of drug administration provide 100% bioavailability?
intradermal injection
intravenous injection
intramuscular injection
subcutaneous injection
Which of the following statements best describes drug dependence?
Discontinuation of the drug will produce withdrawal symptoms
action of one drug is dependent on the presence of another drug
discontinuation of the drug will not produce withdrawal symptoms
patients progressively require increasingly larger doses of a drug to achieve the same effect
An elderly man with hypothyroidism was started on thyroxin. The drug has a half-life of 72 hours. How long will it take to produce full effect?
two days
one week
two weeks
two months
Which of the following studies could establish the drug shelf-life?
bioavailability
bioequivalence
stability studies
pharmacodynamics
An extemporaneous drug label says to store the drug between 15 and 25 degrees centigrade. Which of the following is the most appropriate place where this drug should be stored?
freezer
refrigerator
cool room
warm room
Which of the following describes the best patient instruction regarding the proper way to dispose of needles?
Discard the needles in garbage
Return needles to their original package
Discard the needles in a rigid and resistant container
If the needle is for personal use, you can use it for two times to reduce environment contamination
Cleaning is a very important step when working with laminar flow hoods. Which of the following disinfectants is most suitable for cleaning the hood before compounding a sterile preparation?
70% Ethanol
90% Ethanol
70% Isopropanol
90% Isopropanol
Which of the following is the source for standards for compounding sterile preparations to be followed in the hospital pharmacy?
World Health Organization (WHO) website
Food and Drug Administration (FDA) website
United States Pharmacopeia (USP) chapter 797
Institute for Safe Medication Practices (ISMP) publication
What is the Latin abbreviation for "after meals"?
A.C
A.A
P.C
I.C
Which following best describes the "bio-psychological approach of health"?
Broad view that attributes disease outcome to the variable interaction of biological factors, psychological factors, and social factors
Health constitutes the freedom from disease, pain, or defect, making the normal human condition "healthy"
The scientific measure of health and regards disease as the human body having a breakdown due to a biological reason
The biological component seeks to understand how the cause of the illness stems from the functioning of the individual's body
What is the meaning of off-label drug use?
use of drug without prescription
use of drug expiration date
use of drug outside the hospital
use of drug for unapproved indications
Which of the following statements best represents the intravenous (IV) medication in the hospital facilities?
IV drugs transmit the highest risk of infection
IV drugs are associated with lowest risk of undesirable side effects
IV solutions must be hypotonic to ensure compatibility with blood osmolality
IV medications are free from infection risk
What kind of association between the variables if you want an association between age and depression pre/post drug A use?
two continuous variables
a continuous variable and a binary variable
a continuous variable and an ordinal variable
a continuous variable and a categorical variable
A 23-year-old man has recently been started on phenytoin for the treatment of epilepsy. He is taking no other medication. He has noted recent swelling and bleeding of the gum and wants to know if this might be drug related. Which reference would best address this?
Drug interaction facts
The Harriet Lane handbook
Meyler's Side Effects of Drugs
A pharmacology textbook
Which drug is banned in sport competitions by the international Olympics?
Furosemide
Atenolol
Celecoxib
Diclofenac
Which one is considered a physical examination?
Regulatory
Percussion
Laboratory testing
Administrative screening
A patient on enteral nutrition presents with low phosphate and low magnesium on lab tests. What is the most likely condition?
Refeeding syndrome
Hypocalcemia
Metabolic alkalosis
Dehydration
Using Schilling test to detect amount of which vitamin?
B9
B12
B6
C
When the patient is at rest, the volume of the blood is found more in which location?
vein
arterial
heart
pulmonary circulation
Which IV container needs a filtered needle?
Vial
Bag
Ampoule
All IV preparations need filtered needles
Boxed warning when using for teeth pain in an infant may lead to seizure and death. Which product is implicated?
Clove oil
Ibuprofen suspension
Gel
Acetaminophen drops
What does dose "2 in 1" mean?
Dextrose and amino acids
Water and dextrose
Dextrose and lipoamino acid
Dextrose and amino acids and lipid
Amount of body water in an adult?
60%
70%
80%
90%
Amount of body water in a neonate?
60%
75%
80%
90%
Intra-synovial means?
in spinal
muscle
joint
nerve
A drug that acts via a non-receptor mechanism is which of the following?
Deferoxamine
Desloratadine
Atenolol
None of the above
The place on the body that gives the most accurate temperature is which?
front head
mouth
rectal
axillary
Which of the following can assist in regulation of sleeping pattern?
eating before sleeping by 10 minutes
doing aerobic exercises for 10 minutes
taking several naps during the day
drinking coffee late at night
HIV, TB, and AIDS are best classified as which type of disease?
Chronic disease
Communicable disease
Non-communicable disease
Genetic disease
Carrier of vitamin B12?
Intrinsic factor
Transcobalamin II
Albumin
Hemoglobin
A patient taking Orlistat seeks counseling. Which advice regarding vitamins is appropriate?
Take fat-soluble vitamins at a time separated from Orlistat (before or after)
Take vitamins together with Orlistat to improve absorption
Stop taking all vitamins while on Orlistat
Only take water-soluble vitamins with Orlistat
A woman has signs of vitamin A deficiency. What is one of its natural forms?
Olive oil
Liver oil
Argan oil
Sunflower oil
ISO 7 corresponds to which particle class?
10
100
1,000
10,000
A patient with type 2 diabetes wants to lose weight, has hypertension and heart failure, and has made lifestyle changes and exercises. Which drug choice for DM2 is appropriate?
Insulin
Liraglutide
Metformin
Glyburide
Where is Phase II metabolism found?
Mitochondria
Endoplasmic reticulum
Cytoplasm
Nucleus
Which is the larger lymphoid organ?
intestine
liver
muscle
spleen
Which of the following solutions is used in a central vein?
D5W
0.9% normal saline
3% normal saline
D10W
Affinity refers to which property?
How long a drug binds to receptors
How strongly a drug binds to receptors
How many receptors a drug can bind
How quickly a drug dissociates
Best source of essential fatty acids?
Seafood
Plant
Dairy
Grains
Moderate physical activity is best exemplified by which?
swimming
basketball
brisk walking
heavy weightlifting
