WorksheetsTest review epidemiology
Total questions: 105
Worksheet time: 55mins
What is the definition of Epidemiology ?
Science of looking at health of individuals
Study of distribution and determinants of health-related states among specified individuals
Study of occurence, distribution and determinants of health and disease among specified populations
Study of distribution and determinants of health-related states in order to form treatment options for populations
What do you call something that is likely to be transmitted to people through the environment?
carcinogen
infectious
hazardous
congenital
A reservoir of an infectious agent can be
bugs
An animal
The environment
All of the above
The ______of a particular disease is the number of new cases in a population in a given time period
prevelance
incidence
morbidity
mortality
Which of the following could be used to prevent food-borne illness? Choose all that apply
Wash hands
Cook food thoroughly
Use the same cutting board for uncooked meat and produce
Refrigerate perishable food in two hours
The _____of a given disease is the total number of new and existing disease cases in a population in a given time period
prevalence
incidence
morbidity
mortality
Which among the following is not example of morbidity
Number of people who have cancer
Number of people who have hypertension
Number of patients suffered with Acute Lower Respiratory Tract Infection
Number of people who died from cancer
A toxin or other substance that produces an immune response by the body
Antigen
Antibody
Vaccine
Inanimate objects that can carry pathogens
Fomites
Morbidity
Mortality
Mosquitos
Pathogens that are spread via animals and insects. The animal or insect passes the pathogen to people.
Direct Contact
Indirect Contact
Airborne Transmission
Foodborne Tranmission
Vector-Borne Transmission
The leading causes of death are NOT the leading causes of disability
True
False
When a pathogen is moved from person to person through physical touch (kissing, hugging, close-up sneezing, shaking hands).
Transmission
Translation
Emission
Direct Contact
Indirect Contact
Common vectors for pathogen dispersal include food, water, and air
True
False, "vectors" should be "vehicles"
False, air should not be included
False, but IDK why
___ is the use of microbial agents to incapacitate or kill a military or civilian population in an act of war or terrorism.
Terrorism
Biological warfare
pandemic
none of the above
A person who has a disease without signs and symptoms is a
carrier
resevoir
both
neither
_____ of a pathogen gives a relative picture of its seriousness
number needed to treat (NNT)
Classification
basic reproduction number
(R0)
all of the above
Infectious diseases account for about ___ of all mortality worldwide
20%
25%
30%
35%
Which among the following is not example of morbidity
Number of people who have cancer
Number of people who have hypertension
Number of patients with Acute Lower Respiratory Tract Infection
Number of people who died from cancer
Study of what is upon the people is called
demography
epidemiology
AYUSH
Healthcare
Epidemiologists are interested in learning about --------
the cause of diseases
the frequency and geographic distribution of diseases
how to cure or control them
all of the above
Epidemiology deals with all except
incidence of disease
pathology of diseases
distribution of disease
control of disease
The aim of epidemiology is to---------------health problems and --------------health
eliminate, promote
eradicate, decrease
reduce and promote
eliminate and protect
Which of the following is true about epidemology
improves diagnosis and treatment of disease
eliminate health problems and promote health
monitor health changes over a period of time
all of the above
Which of the following study help in determining the health status of the individual
demography
epidemiology
AYSUH
HSCDS
Epidemiology is the study of the composition of the human population that helps in evaluating effective heath services and programs
part a is right but part b is wrong
part a is wrong but part b is right
both are right
both are wrong
Epidemiology plays an important role in clinical research by periodic assessment of community health
part a is right but part b is wrong
part a is wrong but part b is right
both are right
both are wrong both are wrong
The epidemiological triad consist of an external agent, a susceptible host and an environment where host and agent interact with each other to cause a disease with no role of environent in it.
part a is right but part b is wrong
part b is wrong but part a is right
both are right
both are wrong
Agent in the epidemiological triad can be all except
bacteria
mosquito
virus
parasites
Which of the following environmental factor determine the occurrence of disease.
physical factor
social factor
biological factor
all of these
Physical environment factor includes all except
education
employment level
vector
dietary habits
An organism that carries the disease is called--------
host
agent
environment
all of these
A person or organism infected with an infectious disease agent, but displays no symptoms is called
carrier
agent
vector
all of the above
The epidemiological triad consist of an ; 1.Host, 2. Agents 3. Healthcare facilities 4. Environment , responsible for the occurence of any disease
1 &2
1, 2,3
2, 4th
1, 2, 4
Epidemiology study
causation of disease
Natural history of the diseases
Health status of pipulation
Evaluation of intervention
all of the above
Which of the following factors plays an key role in likelihood of infectious disease acquisition
genetic profile
human behavior
environmental conditions
all of these
The incubation period is the interval between
the time of infection and death
appearance of clinical symptoms
the time of infection and appearance of clinical symptoms
time of infection and appearance ;of antibodies.
Stage of sub clinical diseases, extending from the time of exposure to onset of disease symptoms in chronic disease is called
incubation period
latent period
infection
all of them
Progression of a disease process in an individual over time in the absence of treatment is called
causation of disease
Natural history of disease
Health status of disease
all of them
Epidemiology help us to evaluate the health status of the population to estimate whether time and resources should be spent on particular diseases.
part a is right but part b is wrong
part a is wrong but part b is right
both are right
both are wrong
Epidemiology helps in identifying disease burden in a population. It also determines the priority health programs for prevention and care.
statement 1 is correct but statement 2nd is wrong
statement 1 is wrong but statement 2nd is right
both statement are correct
both the statement are wrong.
Epidemiology helps in assessing the effectiveness of any interventions
True
False
Epidemiological studies are done
making comparisons
asking questions
both of them
none of them
Questions asked during an epidemiological triad include all except
what s the event
what action should be taken by community
what is magnitude
what treatment should be given
What kind of disease can be spread from person to person
communicable
non-communicable
all diseases can be spread
no disease are spread from person to person
What is the difference between communicable and non communicable disease.
a communicable disease can spread from person to person, a non communicable disease comfort
a communicable diseases cannot be passed from person to person while a non communicable disease can be
Both types of disease can be passed from person to person, but communicable diseases require direct contact with bodily fluids.
There will be no difference because both still result in disease.
A pathogen is----------------when it is spread from one person or thing to another
communicable
non-communicable
Diseases
infection
If one got skin cancer from sitting out and tanning in the sun for too long, would that be communicable or non-communicable
non-communicable
communicable
can be anything
none of them
Which of the following is NOT an example of a communicable disease
cold
flu
small pox
asthma
Major changes in the rates of a disease within a population over time provide evidence for which of the following?
Nongenetic factors play an important role in the etiology of that disease
An unknown environmental toxin is triggering the physiological change to the diseased state
Epigenetic factors are playing an outsized role in the development of the disease
Which describes studies that are generally done on healthy people, with an outcome of a disease occurring, and has lower rates?
Prognosis
Risk Factor
Which describes studies that are generally done on sick people, with an outcome of a complications/death/disability/suffering, and has higher rates?
Prognosis
Risk Factor
Hazard ratios are equivalent to which of the following?
Relative risk
Absolute risk
Cohen's d
Attributable risk
Which of the following is a possible explanation for why a condition may not come under medical care? (Note: Choose all that apply.)
The condition is asymptomatic
The symptoms of the condition are considered "normal"
The majority of natural history prognoses are attributable to the decreased availability of service centers in rural areas
If observation begins at different points in the course of disease for the various patients in a cohort, the description of their prognosis will lack precision, and the timing of recovery, recurrence, death, and other outcome events will be difficult to interpret or will be misleading.
True
False
In this study, which of the following is correct population of interest?
Consider the following abstract from the study "Protective effect of myo-inositol hexaphosphate (phytate) on bone mass loss in postmenopausal women".
Introduction: The objective of this paper was to evaluate the relationship between urinary concentrations of InsP6, bone mass loss and risk fracture in postmenopausal women.
Materials and Methods: A total of 157 postmenopausal women were included in the study: 70 had low (≤0.76 μM), 42 intermediate (0.76-1.42 μM) and 45 high (≥1.42 μM) urinary phytate concentrations. Densitometry values for neck were measured at enrollment and after 12 months (lumbar spine and femoral neck), and 10-year risk fracture was calculated using the tool FRAX(®).
Results: Individuals with low InsP6 levels had significantly greater bone mass loss in the lumbar spine (3.08 ± 0.65 % vs. 0.43 ± 0.55 %) than did those with high phytate levels. Moreover, a significantly greater percentage of women with low than with high InsP6 levels showed more than 2 % of bone mass loss in the lumbar spine (55.6 vs. 20.7 %). The 10-year fracture probability was also significantly higher in the low-phytate group compared to the high-phytate group, both in hip (0.37 ± 0.06 % vs 0.18 ± 0.04 %) and major osteoporotic fracture (2.45 ± 0.24 % vs 1.83 ± 0.11 %).
Discussion: It can be concluded that high urinary phytate concentrations are correlated with reduced bone mass loss in lumbar spine over 12 months and with reduced 10-year probability of hip and major osteoporotic fracture, indicating that increased phytate consumption can prevent development of osteoporosis.
All menopausal women
The 157 postmenopausal women included in the study
What type of sampling method was used in this research?
Consider the following extract from "Genetic and Environmental Factors Contributing to Parkinson's Disease: A Case-Control Study in the Cypriot Population. (Links to an external site.)"
A cohort of 235 PD patients and 464 control subjects were recruited from multiple medical and community centers across Cyprus as described previously (16). Patients were included in the study after clinical diagnosis of PD by a board certified neurologist. Diagnosis was followed by a clinical evaluation, using the UPDRS rating scale by a board certified CING neurologist. Patients that had clinical signs suggestive of Parkinsonian syndromes were excluded.
Probability Sample
Random Sample
Convenience Sample
Which of the following is true about the external validity of this study?
Consider the following abstract from "Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib. (Links to an external site.)"
Objectives: To compare the efficacy and safety of chondroitin sulfate plus glucosamine hydrochloride (CS+GH) versus celecoxib in patients with knee osteoarthritis and severe pain.
Methods: Double-blind Multicentre Osteoarthritis interVEntion trial with SYSADOA (MOVES) conducted in France, Germany, Poland and Spain evaluating treatment with CS+GH versus celecoxib in 606 patients with Kellgren and Lawrence grades 2–3 knee osteoarthritis and moderate-to-severe pain (Western Ontario and McMaster osteoarthritis index (WOMAC) score ≥301; 0–500 scale). Patients were randomised to receive 400 mg CS plus 500 mg GH three times a day or 200 mg celecoxib every day for 6 months. The primary outcome was the mean decrease in WOMAC pain from baseline to 6 months. Secondary outcomes included WOMAC function and stiffness, visual analogue scale for pain, presence of joint swelling/effusion, rescue medication consumption, Outcome Measures in Rheumatology Clinical Trials and Osteoarthritis Research Society International (OMERACT-OARSI) criteria and EuroQoL-5D.
Results: The adjusted mean change (95% CI) in WOMAC pain was −185.7 (−200.3 to −171.1) (50.1% decrease) with CS+GH and −186.8 (−201.7 to −171.9) (50.2% decrease) with celecoxib, meeting the non-inferiority margin of −40: −1.11 (−22.0 to 19.8; p=0.92). All sensitivity analyses were consistent with that result. At 6 months, 79.7% of patients in the combination group and 79.2% in the celecoxib group fulfilled OMERACT-OARSI criteria. Both groups elicited a reduction >50% in the presence of joint swelling; a similar reduction was seen for effusion. No differences were observed for the other secondary outcomes. Adverse events were low and similarly distributed between groups.
Conclusions: CS+GH has comparable efficacy to celecoxib in reducing pain, stiffness, functional limitation and joint swelling/effusion after 6 months in patients with painful knee osteoarthritis, with a good safety profile.
The external validity of this study may be limited due to the study design - RCTs require such a high level of control that their wide applicability may be limited
This study has a high degree of external validity due to the controls imposed by the study design
Which type of bias occurs when comparisons are made between groups of patients that differ in ways other than the main factors under study, ones that affect the outcome of the study
Selection Bias
Measurement Bias
Confounding
Which type of bias is present when the way in which a measurement is taken leads to errors in the results on a systematic level.
Selection Bias
Measurement Bias
Confounding
Which of the following research papers could be used to demonstrate a causal relationship?
"A double-blind placebo-controlled randomized trial..."
"A population based study..."
Which of the following studies is the type of study that is really good at providing broad information on a non-specific topic?
The relationship between mercury and autism: A comprehensive review and discussion (Links to an external site.) (Kern, 2016)
Quinine for muscle cramps (Links to an external site.) (El-Tawil, 2015)
Meta-analysis: chondroitin for osteoarthritis of the knee or hip (Links to an external site.) (Reichenbach, 2007)
Kern, 2016
El-Tawil, 2015
Reichenbach, 2007
Which describes an error that resutls in a false positive?
Type 1
Type 2
Which of the following is not an advantage of a recall or record method of data collection?
Allows considerable flexibility in data analysis
Can be easily employed to validate FFQ data
Useful to capture long periods of accurate dietary data for large numbers of people
They are open-ended, allowing for a detailed collection of diverse consumption habits
Which of the following is a major source of errors in 24-hr recall data collection methods?
The use of open-ended questions
The participant's memory
The use of automated computer systems
The use of portion size estimate tools
Which of the following is a method used in dietary records to reduce data collection errors?
Record all foods for the week at one time
Record all foods as they are prepared/consumed
Which of the following is the utility of the FFQ?
Collect precise dietary intakes over a few days
Capture medium- to long-term dietary habits
The use of detailed, long-form questionnaires as eligibility assessments for dietary trials
Which of the following is not a use of a dietary biomarker?
Used as a surrogate for actual dietary intake in studies of disease occurrence
Used as a validation tool for other forms of dietary assessment
Used as a gold-standard intake for all consumed nutrients
Used as a measure of nutrient status
Which of the following is a limitation for recovery biomarkers? (Note: Choose all that apply)
Available for only a very limited number of dietary factors
Recovery biomarkers reflect dietary intakes over a short time period
Reflect absolute intakes of nutrients, whereas we are generally interested in energy-adjusted intakes in nutritional epidemiology
Which of the following is the best option framework for a rapid review of the article Vitamin D status, gender and cardiovascular diseases: a systematic review of prospective epidemiological studies (Links to an external site.)
Amstar
MOOSE
QUARUM
-
Which would be used for a systematic review?
Amstar
MOOSE
QUARUM
-
Which would be used for an RCT?
Amstar
MOOSE
QUARUM
CONSORT
Which of the following would be the preferred method of randomization for an RCT?
Color coded forms
Allocation based upon patient file number
Centralized computer-generated allocation
Which would be used for an observational study?
STROBE
MOOSE
QUARUM
CONSORT
Why is the question of whether a study is retrospective vs. prospective pertinent to the evaluation of cohort studies?
Retrospective studies have a much higher degree of selection bias than do prospective studies.
It is more difficult to control for confounding in prospective studies because new confounding factors come up during the completion of the study.
Prospective studies have a much higher degree of selection bias than do retrospective studies
It is more difficult to control for confounding in retrospective studies because it is impossible or difficult to address missing data.
Which of the following should be given special attention in the evaluation of case-control studies?
Recall bias
Measurement bias
Selection bias
Selection bias
Which of the following is one of the questions that should be considered specifically in the case of evaluating a cross-sectional study?
Were participants and researchers 'blinded' to participants' treatment group?
Were participants and researchers 'blinded' to participants' treatment group?
Is the study retrospective or prospective?
Was a representative sample achieved (e.g. was the response rate sufficiently high)?
Which of the following is a special consideration in case series studies due to the limited size and non-representative nature of the sample?
External validity
Measurement bias
Method of randomization
What is the function of using a gold-standard test in a study of diagnostic accuracy?
They are used to assess specificity but not sensitivity
Provide a standard against which the new diagnostic test can be measured
They are used to assess sensitivity but not specificity
Gold-standard tests are not needed for tests of diagnostic accuracy
Which of the following is not one of the studies of economic evaluation discussed in the reading?
Cost-utility
Cost-profit
Cost-effectiveness
Cost-benefit
Random variation due to chance is as likely to result in measurements above the true value as it is to result in measurements below the true value.
True
False
Why should chance always be a consideration in your evaluation of the research data?
Random variation can be estimated or reduced via improved design, but never eliminated
Chance is more concerning than bias, so it should be the exclusive focus of critical evaluation of research
Random variation can never be estimated for so it represents an unknown factor that must be considered.
Measurements that can be verified physically are difficult to assess for validity, no matter how many times the measurement is repeated.
True
False
Why is the question of relevance so important to establishing content validity for the tool in question?
Content validity does not generally require tight control over included components but the tool in question does due to its procedural components
Content validity requires that all of the dimensions of a particular factor or condition be present in the measurement and most importantly, that dimensions not involved are not included
Content validity seeks to establish a large set of assessments and should include items that are components of the condition and items that are not components of the condition in order to reduce the chance of bias.
Why does the measurement of construct validity sometimes seem less pertinent to clinicians than other physically verifiable measurements?
Construct validity relies up on measures that can not be physically verified;
Third party payors do not like to pay for test that can not be physically verified.
Construct validity has largely been disproven as an effective measure of tools that can not be physically verified.
epidemiological trait composed of
agent ,host,environment
agent,host ,risk factor
agent host,causes
agent ,host,incidence
agent ,host,environment
incidence means
new cases and old case
new cases
new cases and clinical cases
clinical cases band old cases
prevalence
new case and old cases
new cases
old case and clinical cases
old cases
Primary prevention
Early diagnosis and treatment
Health promotion and High risk protection
Disability limitation and rehabilitation
Early diagnosis and health promotion
secondary prevention
early diagnosis and treatment
health promotion and high risk protection
disability limitation and rehabilitation
health promotion and treatment
Tertiary prevention
Early diagnosis and treatment
disability limitation and rehabilitation
health promotion high risk protection
health promotion and prevention
Study proceeds backwards from effect to cause
Case control studies
Cohort Studies
Ecological studies
Prevalence studies
Identified as having particular disease, health disorder or
condition Under investigation is called
case
control
carrier
sub clinical case
Disease agent multiply in the host but does
not manifest by signs and symptoms
Sub clinical cases
clinical cases
case
incubation period
Person who acquires the disease from an exposure to the primary case is called
Secondary Case
Index Case
Primary Case
Tertiary Case
Which of the following recent widespread disease is considered pandemic?
Ebola virus disease
H1N1 flu virus (swine flu)
SARS CoV-2
Measles
Endemic means that a disease:
Occurs clearly in excess of normal expectancy
Is habitually present in human populations
Affects a large number of countries simultaneously
Exhibits a seasonal pattern
Is prevalent among animals
The first table shows the total number of persons who ate each of two specified food items that were possibly infective with group A streptococci. The second table shows the number of sick persons (with acute sore throat) who ate each of the various specified combinations of the food items.
What is the sore throat attack rate in persons who ate both egg salad and tuna?
60/75
60/275
70/200
60/135
None of the above
The first table shows the total number of persons who ate each of two specified food items that were possibly infective with group A streptococci. The second table shows the number of sick persons (with acute sore throat) who ate each of the various specified combinations of the food items.
According to the results shown in the preceding tables, which of the following food items (or combination of food items) is most likely to be infective?
Tuna only
Egg salad only
Neither tuna nor egg salad
Both tuna and egg salad
Cannot be calculated from the data given
In the study of an outbreak of an infectious disease, plotting an epidemic curve is useful because:
It helps to determine what type of outbreak (e.g., single-source, person-to-person) has occurred
It shows whether herd immunity has occurred
It helps to determine the median incubation period
a and c
a, b, and c
Which of the following is characteristic of a single-exposure, common-vehicle outbreak?
Frequent secondary cases
Increasing severity with increasing age
Explosive
Cases include both people who have been exposed and those who were not exposed
All of the above
