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Recombinant DNA technology

Total questions: 20

Worksheet time: 20mins

Name
Class
Date
1.

What is a recombinant DNA?

a)

DNA from 2 different organisms combined

b)

DNA from 2 different ribosomes

c)

DNA that is separated out from a vector

2.

Which of the following could be used as a vector for a human gene?

a)

Bacterial Plasmid

b)

Bacteria

c)

A mitochondria

d)

mRNA

3.

A circular piece of DNA, found in bacteria, is called:

a)

A plasmid

b)

mRNA

c)

Ribosome

d)

Nucleotide

4.
Plasmids, yeast, and viruses are known as ____________.
a)
restriction enzymes
b)
vectors
c)
genetically modified organisms
d)
bacteria
5.
Which is used to cut DNA molecules at specific points?
a)
gel electrophoresis
b)
PCR analysis
c)
a restriction enzyme
d)
recombinant DNA
6.

Bacteria cells can be used to produce insulin for the treatment of diabetes in humans. Which best explains how the bacteria cells are able to produce insulin for humans?

a)

The bacteria have been grown on a petri dish containing insulin.

b)

The bacteria have been genetically engineered to contain the DNA needed to produce insulin.

c)

The bacteria have been exposed to radioactivity to create mutant strains capable of producing insulin.

d)

The bacteria have been grown on a petri dish containing sugar; the bacteria produce insulin in response to the sugar.

7.

Which of the following is a protein that acts as DNA "scissors"?

a)

plasmid

b)

restriction enzyme

c)

ligase

d)

protein expression

8.
mRNA is converted to cDNA by ………………
a)
Ligase enzyme
b)
Reverse Transcriptase enzyme
c)
Restriction Endonuclease enzyme
d)
RNA polymerase enzyme
9.

Which of the following terms describes the process of the uptake of recombinant plasmids into bacteria cells?

a)

amplification

b)

insertion

c)

transformation

d)

screening

10.

Restriction enzymes found in bacterial cells are naturally used:

a)

During DNA replication.

b)

To degrade the bacterial cell's DNA.

c)

To degrade viral DNA that enters the cell.

d)

To attach pieces of DNA together.

11.

What is the purpose of amplification?

a)

To screen for recombinant bacteria.

b)

To join the rDNA with the host cell.

c)

To produce multiple copies of the desired gene.

d)

To prevent the bacteria from reproducing.

12.

Restriction endonucleases cut DNA at a specific site called

a)

ligation site

b)

ori

c)

recognition sequence

d)

replication site

13.

In genetic engineering, DNA ligase is used as:

a)

a probe

b)

a sealing enzyme

c)

a restriction enzyme

d)

a mutagen

14.

An organism that has had its genes manipulated by genetic engineering is considered as ___.

a)

transgenic

b)

crossbred

c)

transmutant

d)

culitvars

15.

Which of the following is used as selectable marker?

a)

Ampicillin resistance gene

b)

Plasmid resistance gene

c)

Salmonella resistance gene

d)

Penicillin resistance gene

16.

What is the significance of the lacZ gene in cloning?

a)

It provides antibiotic resistance

b)

It is involved in DNA replication

c)

It allows for blue-white screening

d)

It encodes a fluorescent protein

17.

What is the main function of PCR in recombinant DNA technology?

a)

To ligate DNA

b)

To sequence DNA

c)

To isolate DNA

d)

To amplify DNA

18.
What type of macromolecule are restriction enzymes?
a)
nucleic acid
b)
carbohydrate
c)
protein
d)
lipid
19.
What substance is used to "stain" the DNA for viewing under a UV light?
a)
ethidium bromide
b)
bromothymol blue
c)
TBE buffer
d)
agarose gel
20.

bacteriophages (bacterial viruses) participate in this gene transfer

a)

transformation

b)

conjugation

c)

transduction

d)

translation