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Pathology Quiz

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

A 68-year-old male suffers an ischemic stroke. Histological examination of the brain tissue weeks later would most likely reveal which type of necrosis?

a)

Coagulative necrosis

b)

Liquefactive necrosis

c)

Fibrinoid necrosis

d)

Fat necrosis

2.

The accumulation of "Lipofuscin" pigment in the heart of an elderly patient is a marker of:

a)

Acute radical damage

b)

Recent myocardial infarction

c)

Past lipid peroxidation and "wear-and-tear"

d)

Iron overload (Hemosiderosis)

3.

A "Paradoxical Embolus" is an embolus that:

a)

Originates in the arteries and lodges in the veins

b)

Originates in the venous circulation but enters the systemic arterial circulation via a heart defect

c)

Is composed of amniotic fluid

d)

Travels retrograde against the blood flow

4.

Which of the following is a component of Virchow’s Triad regarding the pathogenesis of thrombosis?

a)

Hypercalcemia

b)

Endothelial injury

c)

Hypoproteinemia

d)

Thrombocytopenia

5.

The term "Desmoplasia" in a malignant tumor refers to:

a)

The degree of cellular undifferentiation

b)

Abundant collagenous stroma induced by the tumor

c)

The spread of tumor to regional lymph nodes

d)

The formation of new blood vessels

6.

Which of the following is a "Tumor Suppressor Gene" that acts as the "Guardian of the Genome" by inducing cell cycle arrest?

a)

RAS

b)

MYC

c)

TP53

d)

HER2/neu

7.

A "Paraneoplastic Syndrome" characterized by Hypercalcemia is most commonly associated with the secretion of:

a)

ACTH

b)

Erythropoietin

c)

Parathyroid hormone-related protein (PTHrP)

d)

Antidiuretic hormone

8.

Which of the following is the most common route for the metastasis of "Carcinomas"?

a)

Hematogenous spread

b)

Lymphatic spread

c)

Seeding of body cavities

d)

Retrograde axonal transport

9.

"Dystrophic" granulation tissue consists primarily of:

a)

Dense collagen and few vessels

b)

New capillaries, fibroblasts, and inflammatory cells

c)

Areas of caseous necrosis

d)

Mature elastic fibers

10.

Which cytokine is the "Master Regulator" of the acute phase response, inducing the liver to produce C-reactive protein (CRP)?

a)

IL-1

b)

TNF-alpha

c)

IL-6

d)

Interferon-gamma