WorksheetsGLP-1 Analogue
Total questions: 20
Worksheet time: 3mins
Incretins are
Steroid hormones
Peptide hormones
Enzymes
Neurotransmitters
Main incretin hormones are
Insulin and Glucagon
GLP-1 and GIP
Cortisol and Aldosterone
T3 and T4
GIP is secreted from
L cells of ileum
K cells of duodenum
Alpha cells of pancreas
Beta cells of pancreas
GLP-1 is secreted from
K cells
L cells
D cells
Acinar cells
GLP-1 stands for
Glucose like protein
Glucagon like peptide-1
Growth like peptide
Glycogen lowering peptide
GIP full form is
Gastric inhibitory peptide
Glucose independent peptide
Glucose dependent insulinotropic peptide
Growth inducing peptide
GLP-1 mainly increases secretion of
Glucagon
Insulin
Cortisol
Growth hormone
GLP-1 reduces
Appetite
Heart rate
Blood pressure
Body temperature
Incretin effect means
More insulin after oral glucose than IV glucose
Less insulin after oral glucose
Equal insulin after oral and IV glucose
No insulin release
GLP-1 slows
Renal filtration
Gastric emptying
Lung ventilation
Bile secretion
GLP-1 analogues are used in
Type 1 diabetes
Type 2 diabetes
Hypothyroidism
Cushing’s syndrome
GLP-1 also helps in
Weight gain
Weight loss
Fluid retention
Bone loss
GLP-1 suppresses
Insulin
Glucagon
Growth hormone
Prolactin
GLP-1 receptors are present in
Pancreas only
Brain only
Pancreas and brain
Liver only
Natural GLP-1 is rapidly destroyed by
Amylase
DPP-4 enzyme
Lipase
Pepsin
GLP-1 analogues are resistant to
Insulin
DPP-4
Trypsin
Renin
GIP mainly acts on
Alpha cells
Beta cells
Delta cells
PP cells
Incretins are released after
Exercise
Stress
Meal intake
Sleep
GLP-1 has how many amino acids (active form)?
15
21
31
50
Major clinical benefit of GLP-1 analogues is
Hypoglycemia
Weight gain
Better glycemic control with weight loss
Hypertension
