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Tumor Markers and Cancer Quiz

Total questions: 21

Worksheet time: 11mins

Name
Class
Date
1.

Tumor markers are primarily used for

a)

Definitive diagnosis of cancer

b)

Screening all cancers

c)

Monitoring therapy and detecting recurrence

d)

Treating cancer

2.

Most specific tumor marker for prostate carcinoma is

a)

AFP

b)

CEA

c)

PSA

d)

CA-125

3.

AFP is a tumor marker for

a)

Hepatocellular carcinoma and yolk sac tumor

b)

Colon cancer

c)

Prostate cancer

d)

Ovarian serous carcinoma

4.

CEA is commonly elevated in

a)

Cervical cancer

b)

Colorectal carcinoma

c)

Prostate carcinoma

d)

Renal carcinoma

5.

CA-125 is a marker for

a)

Ovarian carcinoma

b)

Thyroid carcinoma

c)

HCC

d)

Gastric carcinoma

6.

CA 19-9 is associated with

a)

Breast carcinoma

b)

Pancreatic carcinoma

c)

Prostate carcinoma

d)

Testicular tumor

7.

Beta-hCG is elevated in

a)

Seminoma only

b)

Choriocarcinoma and germ cell tumors

c)

Colon carcinoma

d)

HCC

8.

Paraneoplastic syndrome is best defined as

a)

Direct tumor invasion effects

b)

Symptoms due to metastasis

c)

Symptom complexes not explained by local or metastatic tumor spread

d)

Infection due to tumor

9.

Paraneoplastic hypercalcemia is commonly due to secretion of

a)

PTH

b)

PTHrP

c)

Calcitonin

d)

Vitamin D

10.

Paraneoplastic Cushing syndrome is due to ectopic production of

a)

ACTH

b)

TSH

c)

PTH

d)

GH

11.

Cancer grading is based on

a)

Extent of spread

b)

Histologic degree of differentiation

c)

Presence of metastasis

d)

Patient age

12.

Cancer staging indicates

a)

Tumor differentiation

b)

Extent of spread and prognosis

c)

Cellular atypia only

d)

Genetic mutation type

13.

TNM staging system includes

a)

Tumor size

b)

Node involvement

c)

Metastasis

d)

All of the above

14.

Neuroblastoma arises from

a)

Neural crest cells

b)

B cell lineage

c)

Epithelial cells

d)

Endothelial cells

15.

Common site of neuroblastoma is

a)

Thyroid

b)

Adrenal medulla

c)

Pancreas

d)

Testis

16.

Neuroblastoma commonly shows which histologic feature?

a)

Reed-Sternberg cells

b)

Psammoma bodies

c)

Homer-Wright rosettes

d)

Aschoff bodies

17.

Benign neoplasms are typically

a)

Invasive

b)

Well circumscribed and encapsulated

c)

Poorly differentiated

d)

Metastatic

18.

Benign tumors usually show

a)

High mitotic activity

b)

Anaplasia

c)

Slow growth

d)

Early metastasis

19.

Oncogenic viruses contribute to cancer by

a)

Directly forming granulomas

b)

Inducing chronic inflammation only

c)

Incorporating oncogenes or inactivating tumor suppressors

d)

Producing toxins only

20.

High-risk HPV causes cancer mainly by

a)

E6 and E7 oncoproteins

b)

E1 and E2 proteins

c)

gp120

d)

Reverse transcriptase

21.

EBV is associated with all EXCEPT

a)

Burkitt lymphoma

b)

Nasopharyngeal carcinoma

c)

Some Hodgkin lymphoma

d)

Cervical carcinoma