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Microbiology Quiz

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

A 25-year-old student presents with a dry cough and "walking pneumonia." The laboratory report states the causative organism lacks a peptidoglycan cell wall. Which antibiotic would be inherently ineffective?

a)

Azithromycin

b)

Doxycycline

c)

Benzylpenicillin

d)

Levofloxacin

2.

Which of the following bacterial toxins is a superantigen that binds directly to Class II MHC molecules and T-cell receptors, leading to a massive cytokine storm?

a)

Tetanospasmin

b)

Toxic Shock Syndrome Toxin-1 (TSST-1)

c)

Diphtheria toxin

d)

Cholera toxin

3.

A Gram-negative, comma-shaped rod is isolated from the stool of a patient with profuse "rice-water" diarrhea. The organism is oxidase-positive and grows on TCBS agar. What is the most likely organism?

a)

Escherichia coli

b)

Salmonella typhi

c)

Vibrio cholerae

d)

Shigella dysenteriae

4.

Which specific component of the Gram-negative cell wall is synonymous with "Endotoxin"?

a)

Teichoic acid

b)

Peptidoglycan

c)

Lipid A

d)

Periplasmic space

5.

A patient presents with a painless, hard ulcer on the glans penis. Dark-field microscopy of the lesion exudate shows motile spirochetes. What is the causative agent?

a)

Borrelia burgdorferi

b)

Leptospira interrogans

c)

Treponema pallidum

d)

Haemophilus ducreyi

6.

Which of the following organisms is a "strictly anaerobic," spore-forming Gram-positive rod that causes gas gangrene?

a)

Clostridium perfringens

b)

Bacillus anthracis

c)

Listeria monocytogenes

d)

Corynebacterium diphtheriae

7.

In the lab, a "Satellitism" test is performed where Haemophilus influenzae grows only around colonies of Staphylococcus aureus. What factor is S. aureus providing to allow this growth?

a)

Factor X (Hemin)

b)

Factor V (NAD)

c)

Factor IX

d)

Cysteine

8.

Which pigment, produced by Pseudomonas aeruginosa, is responsible for the blue-green color often seen in burn wound infections?

a)

Pyocyanin

b)

Prodigiosin

c)

Staphyloxanthin

d)

Melanin

9.

A patient with suspected Tuberculosis has a positive Acid-Fast stain. Which molecule in the cell wall is responsible for this staining characteristic?

a)

Ergosterol

b)

Mycolic acid

c)

Lipopolysaccharide

d)

Dipicolinic acid

10.

A diabetic patient presents with a rapidly progressing necrotic infection of the nose and orbit (Rhinocerebral mucormycosis). Microscopy shows broad, non-septate hyphae branching at 90-degree angles. Which genus is likely responsible?

a)

Aspergillus

b)

Rhizopus

c)

Candida

d)

Cryptococcus

11.

Which fungus exists as an encapsulated yeast and is typically identified using an India Ink preparation of cerebrospinal fluid?

a)

Candida albicans

b)

Cryptococcus neoformans

c)

Histoplasma capsulatum

d)

Blastomyces dermatitidis

12.

A "Germ Tube Test" is positive if the organism produces true hyphae without constriction when incubated in serum. This test is diagnostic for:

a)

Candida glabrata

b)

Candida albicans

c)

Aspergillus fumigatus

d)

Sporothrix schenckii

13.

A patient presents with Tinea versicolor, showing "Spaghetti and meatballs" appearance on KOH mount. Which fungus is the culprit?

a)

Microsporum canis

b)

Trichophyton rubrum

c)

Malassezia furfur

d)

Epidermophyton floccosum

14.

Which dimorphic fungus is endemic to the Ohio and Mississippi River Valleys and is characterized by small intracellular yeasts found inside macrophages?

a)

Coccidioides immitis

b)

Histoplasma capsulatum

c)

Paracoccidioides brasiliensis

d)

Blastomyces dermatitidis

15.

A gardener develops a chain of subcutaneous nodules on his arm after a rose-thorn prick. This clinical presentation is characteristic of:

a)

Sporothrix schenckii

b)

Madurella mycetomatis

c)

Fonsecaea pedrosoi

d)

Candida tropicalis