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WorksheetsPharmacology Week 3 Part 3
Total questions: 23
Worksheet time: 12mins
A patient diagnosed with ocular rosacea requires management. Based on the classification of rosacea subtypes, which clinical presentation would you expect to find?
Thickening of the skin on the nose (rhinophyma)
Blepharitis or conjunctival injection
Central facial flushing triggered by spicy foods
Recurrent honey-colored crusting on the perioral region
A pharmacy receives a prescription for oral isotretinoin. According to the iPLEDGE REMS requirements, what is the maximum day supply that can be dispensed at one time?
7-day supply
14-day supply
30-day supply
90-day supply
Which of the following describes the mechanism of action for the antiviral agents acyclovir and valacyclovir?
Inhibition of bacterial protein synthesis
Inhibition of viral DNA polymerase and DNA chain termination
Blockade of the androgen receptor
Inhibition of fungal ergosterol synthesis
According to the objectives, what is the primary mechanism of action for the antibacterial agents used in treating skin and soft tissue infections (SSTIs)?
Inhibition of cell wall synthesis or protein synthesis
Disruption of the fungal cell membrane
Competitive inhibition of viral protease
Vasoconstriction of superficial blood vessels
Which of the following statements regarding the newer acne agent clascoterone (Winlevi) is correct?
It is an oral antibiotic used for severe acne
It is a topical androgen receptor inhibitor used when initial topical therapies fail
It is the preferred treatment for Ramsay–Hunt syndrome
It is a Pregnancy Category X systemic medication
A patient is being treated for acne with a topical retinoid. Which of the following agents is classified as Pregnancy Category X?
Benzoyl peroxide
Topical clindamycin
Tazarotene
Azelaic acid
A patient with rosacea is instructed to keep a symptom diary. What is the primary purpose of this clinical recommendation?
To monitor for systemic signs of infection such as fever
To track the progression of comedone formation
To identify specific triggers such as spicy foods, alcohol, heat, or caffeine
To document the timing of monthly pregnancy tests
Which of the following medications used for the persistent redness of erythematotelangiectatic rosacea works specifically through vasoconstriction?
Ivermectin
Brimonidine
Metronidazole
Minocycline foam
In addition to tazarotene, which of the following topical retinoids is specifically identified in the objectives as Pregnancy Category X?
Adapalene
Trifarotene
Tretinoin
Clascoterone
According to the treatment sequencing for moderate acne, which of the following is a recommended first-line combination strategy?
Retinoid + benzoyl peroxide + topical antibiotic
Oral isotretinoin + topical retinoid
Topical mupirocin + oral cephalexin
Oral penicillin VK + benzoyl peroxide
A patient is prescribed oral terbinafine for a systemic fungal infection. In addition to liver function tests, what other parameter must be monitored?
Serum electrolytes
Renal function
Complete blood count with differential
Fasting blood glucose
Which characteristic feature of acne vulgaris is notably absent in the clinical presentation of rosacea?
Pustules
Papules
Comedones
Erythema
In addition to Streptococcus pyogenes, which organism is explicitly listed in the objectives as a common pathogen in necrotizing infections?
Pasteurella multocida
Clostridium species
Eikenella corrodens
Cutibacterium acnes
Which pathogen must be specifically considered for diabetic foot infections, particularly when those infections are moderate to severe?
Pseudomonas aeruginosa and anaerobes
Varicella-zoster virus
Staphylococcus epidermidis only
Candida albicans
According to Objective 6, which clinical step is critical for a patient on acyclovir to prevent crystal-induced renal injury?
Maintaining adequate hydration
Routine fasting lipid panels
Monthly pregnancy tests
Monitoring for hepatotoxicity
Which medication is indicated for the treatment of severe recalcitrant acne or treatment-resistant moderate acne and requires a 30-day maximum supply?
Oral isotretinoin
Oral doxycycline
Topical mupirocin
Topical clascoterone
A patient presents with a single, small, honey-colored crusted lesion on the arm. According to the objectives, which is the most appropriate first-line treatment for this mild, localized impetigo?
Oral cephalexin
Oral dicloxacillin
Topical mupirocin
IV vancomycin
A patient with extensive impetigo and a known severe beta-lactam allergy requires oral therapy. Which of the following is an appropriate alternative listed in the objectives?
Oral cephalexin
Oral penicillin VK
Oral doxycycline
Topical retapamulin
Which of the following fungal infections can be appropriately managed with over-the-counter (OTC) topical antifungal agents?
Tinea capitis
Tinea unguium
Tinea corporis
Onychomycosis
A patient is being treated for a severe varicella-zoster complication with IV acyclovir. What is the primary reason for maintaining adequate hydration in this patient?
To prevent drug-induced hepatotoxicity
To prevent crystal-induced renal injury
To reduce the risk of Ramsay–Hunt syndrome
To ensure the drug reaches therapeutic levels in the CSF
Which of the following medications is uniquely identified as a topical androgen receptor inhibitor for the treatment of acne?
Tazarotene
Clascoterone
Trifarotene
Isotretinoin
A patient with rosacea presents with thickening of the skin and a bulbous appearance of the nose (phymatous subtype). If the area is currently inflamed, which of the following is a recommended systemic treatment?
Oral tetracycline
Topical brimonidine
Topical metronidazole
Laser therapy
In the management of diabetic foot infections (DFIs), which clinical presentation typically involves a monomicrobial infection requiring narrow-spectrum oral therapy?
Severe infection
Moderate infection
Mild infection
Necrotizing infection
