Glycolysis and Citric Acid Cycle flashcards

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Glycolysis location

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Cytoplasm

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Net gain from glycolysis

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2 ATP, 2 NADH

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Key enzymes in glycolysis

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Hexokinase, Phosphofructokinase-1 (PFK-1), Pyruvate kinase

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Oxygen requirement for glycolysis

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Anaerobic (no oxygen needed)

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Location of Pyruvate Dehydrogenase Complex (PDC)

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Mitochondrial Matrix

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Conversion in Pyruvate Dehydrogenase Complex

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2 Pyruvate to 2 Acetyl-CoA + 2 CO2

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NADH production in PDC

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2 NADH (1 per pyruvate)

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Key enzyme in PDC

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Pyruvate dehydrogenase (multi-enzyme complex)

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Cofactors required for PDC

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TPP (from Vitamin B1), Lipoic acid, CoA (from Vitamin B5), FAD (from Vitamin B2), NAD+ (from Vitamin B3)

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Location of Citric Acid Cycle

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Mitochondrial Matrix