Steroid Hormones

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All steroid hormones are derived from cholesterol and differ only in the ring structure and side chains attached to it.

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Steroid hormones share a common origin from cholesterol, with variations in their ring structures and side chains.

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Steroid hormones are soluble in fat.

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The solubility of steroid hormones in fat allows them to easily pass through cell membranes.

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Diagram of the basic steroid structure.

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The diagram illustrates the core structure of steroids, highlighting the carbon positions in the rings.

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Cortisol and hydrocortisone are interchangeable terms in some contexts.

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Hydrocortisone is another name for cortisol, the primary glucocorticoid in humans.

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Prednisolone is the drug of choice for systemic application.

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Prednisolone is preferred for systemic treatments due to its effectiveness.

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Chemical structure of cortisol (hydrocortisone) showing its molecular arrangement.

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This diagram represents the molecular structure of cortisol, a naturally occurring corticosteroid.

Front

Prednisone and prednisolone differ in their functional groups at position 11.

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Prednisone has a ketone group at position 11, while prednisolone has a hydroxyl group at the same position.

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Chemical structure of Dexamethasone.

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Dexamethasone's chemical structure shows modifications that make it 30 times more potent than cortisol and eliminate sodium-retaining effects.

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Clinical uses of estrogens include replacement therapy for conditions like Turner syndrome and menopause.

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Estrogens are used in contraception as one of their clinical applications.

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Testosterone's role in spermatogenesis.

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Testosterone plays a significant role in the production and development of sperm cells.