Chapter 3 In-Class Problems

Chapter 3 In-Class Problems

If uncoiled, the DNA in all the cells in your body to Pluto and back. True or False?

• One cell’s DNA stretched out is ~2 m long

• One bp is 0.34 nm (3.4 Å)
  

• ~6 billion bp in the human genome

• ~10^13 cells in the human body

• 7.5 billion km to Pluto

Multiple Choice

Consider the following data regarding double-stranded DNA:

Type of supercoil: positive

Twist number: 50

Writhe number: 4

Calculate the linking number for this DNA.

• 46

• 50

• 54

• Not enough information provided

Multiple Choice

Consider a relaxed, closed-circular 210-bp DNA molecule. What is the linking number? What is the linking number if the DNA is cleaved, two turns are removed, and sealed together again?

• 20, 18

• 20, 22

• 617, 18

• 617, 22

• None of these