SI Session 4/4

Multiple Choice

Given the picture of the T-cell receptor, what is is the brown, red, and blue regions respectively?

• Antigen, antibody, antigen-antibody complex

• Antigen, constant, variable

• Antibody, variable, constant

• Antigen, variable, constant

Multiple Choice

What is FALSE about T cells?

• Mature T cells are naive until they are activated by antigen presentation

• Once activated, they proliferate into effector and memory cells

• T cells are born and matured in the bone marrow

• 3 types: T helper, cytotoxic T lymphocytes, regulatory T cells

Multiple Choice

What is FALSE about T-helper cells?

• TH0 is an undifferentiated precursor of the other types of T cells, excluding T reg

• One of the types, T reg, recognizes foreign antigens

• There are 5 types

• Activated by antigens presented on MHC Class II

Multiple Choice

What is FALSE about cytotoxic T cells?

• Naive CD4+ T-cells

• Expresses an antigen-specific T-cell receptor

• Mature into CTL upon antigen recognition

• Has Perforin & Fas-FasL Pathways

Multiple Choice

Which of the following does not contribute to antibody diversity?

• Class switching

• Splice-site variability

• Somatic hypermutation

• Antigen receptors

Multiple Choice

What is TRUE about Staphylococcus aureus Protein A?

• Non-specifically binds antigens

• Does not bind the Fc region usually

• Rod shaped

• Virulence determinant deposited on cell surface

Multiple Choice

What is the definition of somatic hypermutation of V regions?

• Region of DNA that can have a high rate of induced mutation. V regions are susceptible to this.

• During splicing, the junction between the V and D and J segments can be changed

• Antibody genes are split into many gene segments

• None of the above <3