Basal Nuclei

Multiple Choice

A 56-year-old woman presents with a stroke involving the medial striate artery (of Heubner). Which of the following areas are likely to be affected?

• Areas A and B

• Areas B and C

• Areas C and D

• Areas D and E

• Areas E and F

Multiple Choice

The caudate and putamen are collectively known as:

• Striatum

• Globus pallidus

• Subthalmic nucleus

• Substantia nigra

Multiple Choice

A 36-year-old woman presents with a tumor affecting the lateral wall of

the anterior horn of the lateral ventricle. Which of the following structures

might be affected?

• Caudate nucleus, head

• Caudate nucleus, tail

• Putamen

• Globus pallidus

• Dorsomedial nucleus of thalamus

Multiple Choice

A 52-year-old female patient presents with violent and flinging movements of his left upper limb. The abnormal movements started about a week ago and seem to primarily affect his proximal limb muscles. Which of the following structures is the origin of this patient's abnormal movement?

• Caudate

• Subthalamic nucleus

• Substantia nigra

• Motor cortex

• Globus pallidus internal

Multiple Choice

At rest, the globus pallidus internus (GPi) ____the thalamus

• •Excites

• •Inhibits

• •Both of the above

Multiple Choice

Which of the following is the correct sequence of structures in the direct pathway of movement?

• Cortex, striatum, globus pallidus pars externa, subthalamic nucleus, thalamus, cortex

• Cortex, striatum, globus pallidus pars interna, subthalamic nucleus, thalamus, cortex

• Cortex, striatum, globus pallidus pars interna, thalamus, cortex

• Cortex, striatum, globus pallidus pars interna, subthalamic nucleus, globus pallidus, pars externa, thalamus, cortex

• Cortex, globus pallidus pars externa, striatum, subthalamic nucleus, thalamus, cortex

Multiple Choice

Fill in the blank: The basal ganglia indirect

pathway involves _______________ and then the

_______________.

• The globus pallidus externa and then the subthalamic

  nucleus

• The globus pallidus interna and then the subthalamic

  nucleus

• The substantia nigra pars compacta and then the substantia

  nigra pars reticularis

• The raphe nucleus and then the substantia nigra pars

  compacta

Multiple Choice

The substantia nigra activates the D1/2 pathway via the

• Nigrostriatal pathway

• Corticostriatal pathway

• Thalamocortical pathway

• None of the above

Multiple Choice

D1 and D2 receptors are located where in the basal ganglia?

• Putamen

• Substantia nigra

• Subthalamic nucleus

• Thalamus

Multiple Choice

An increase in D1/direct pathway will lead to

• Slower movements

• Faster movements

• More finer/coordinated movement

• •None of the above