Human Genetics pedigree 24-25

Half colored symbols represent a heterozygous genotype.
These people are often called carriers, as they have the gene of the trait or disease, but do not present the phenotype.
They have a 50% chance of passing on the gene to their offspring.

Carriers

Multiple Choice

What is this?

• Pedigree
• Karyotype
• Venn diagram
• Punnett Square

Multiple Choice

What do we use pedigrees for?

• To look at families
• To make determinations about the offspring
• To track traits in families
• Nothing

Multiple Choice

In a pedigree, what shape represents a male?

• circle
• square
• triangle
• diamond

Multiple Choice

How many generations are shown in this pedigree?

• 1
• 2
• 3
• 4

Multiple Choice

What does an open circle represent?

• Not Affected Male
• Not Affected Female
• Affected Male
• Affected Female

Multiple Choice

What does a filled in square represent?

• Not affected Female
• Not affected Male
• Affected Male
• Affected Female

Multiple Choice

What does a horizontal line between a square and a circle mean?

• They are siblings
• They are cousins
• They are married ("together") or crossed

• They are the children

Multiple Choice

What does a vertical line coming down from a square and circle that are connected by horizontal line indicate?

• They are cousins
• The children
• Aunts and Uncles

Multiple Choice

AA and Aa always show up as

• dominant
• recessive

Multiple Choice

aa always shows up as

• dominant
• recessive

Multiple Choice

In the second generation-how many people are carriers of the trait?

• 2
• 3
• 5
• 6

Multiple Choice

In the second generation of this pedigree, how many people are carriers of the trait? *Remember: a carrier does not have the disorder/disease, but can pass it on to his/her children.

• 1

• 2

• 3

• 5

Multiple Choice

The trait this pedigree traces is recessive because it skips a generation and individuals can be carriers. What is the most likely genotype for person III-3?

• GG

• Gg

• gg

Multiple Choice

This trait is recessive.  What is the genotype for person II-1?

• GG
• Gg
• gg
• can't be determined

Multiple Choice

How many kids did the mother and father from the first generation have?

• 2

• 4

• 5

• 6

Multiple Choice

How many children did I-3 and I-4 have?

• 2
• 3
• 4
• 5

Multiple Choice

Why is it important to study patterns of inheritance in human genetics?

• To understand how traits and diseases are passed down in families

• To predict the weather

• To learn about animal behavior

• To improve computer technology

Multiple Choice

Which symbol is used to represent a male with the phenotype of interest in a pedigree chart?

• A filled square

• A filled circle

• A half-filled square

• A diamond

Multiple Choice

In a pedigree chart, what do Roman numerals typically represent?

• Individuals

• Generations

• Phenotypes

• Siblings

Multiple Select

Which of the following clues indicate that a disease is autosomal dominant according to the pedigree chart for Huntington’s Disease?

• It is present in every generation

• It affects both males and females

• It affects only males

• It skips generations

Open Ended

Explain how you would determine if a trait is sex-linked or autosomal by analyzing a pedigree chart.

Multiple Choice

What is the inheritance pattern shown in the pedigree chart for Hemophilia in the Royal Families?

• Autosomal dominant

• Autosomal recessive

• Sex-linked recessive

• Mitochondrial

Multiple Choice

Which of the following clues indicate that a disease is inherited in an autosomal recessive manner?

• It affects both males and females and can skip a generation.

• It only affects males.

• It is always present in every generation.

• It only affects females.

Multiple Choice

In an autosomal recessive pedigree, individuals who are carriers are:

• Heterozygous for the trait

• Homozygous dominant

• Homozygous recessive

• Not affected and do not carry the gene

Open Ended

Explain the significance of carriers in an autosomal recessive pedigree and how they contribute to the inheritance of the trait.

Open Ended

What is one question you still have about pedigree charts or how they are used in genetics?

Open Ended

How does a pedigree chart help in understanding genetic inheritance patterns within a family?