Mutation Practice

Multiple Choice

Changes is DNA sequences that affect genetic information are known as

• replications

• mutations

• transformations

• translations

Multiple Choice

Which of the following best describes a mutation?

• A change in the genetic material

• A normal process of cell division

• A type of protein synthesis

• A method of energy production

Multiple Choice

Which of the following best describes the difference between gene mutations and chromosomal mutations?

• Gene mutations affect a single gene, while chromosomal mutations involve changes in the number or structure of chromosomes.

• Gene mutations only occur in chromosomes, while chromosomal mutations occur in genes.

• Gene mutations always cause diseases, while chromosomal mutations do not.

• Gene mutations are always inherited, while chromosomal mutations are not.

THE CAT ATE THE RAT

THE CAT ACE THE RAT

Multiple Choice

A point mutation occurs when a single base is changed in a DNA sequence. What is the main type of point mutation?

• Substitution

• Insertion

• Deletion

• Duplication

Multiple Choice

Which of the following statements about silent mutations is correct?

• A silent mutation changes the amino acid sequence of a protein.

• A silent mutation results in a stop codon.

• A silent mutation does not change the amino acid sequence of a protein.

• A silent mutation deletes a base from the DNA sequence.

Fill in the Blanks

Substitution mutations can be classified as

mutations when they result in a premature stop codon.

Multiple Select

Which of the following are examples of frameshift mutations? (select 2)

• Insertion

• Deletion

• Substitution

• Duplication

Multiple Choice

Which type of frameshift mutation involves the addition of a base into the DNA sequence?

• Insertion

• Deletion

• Substitution

• Translocation

Multiple Choice

How does a deletion frameshift mutation affect the resulting amino acid sequence compared to an insertion frameshift mutation?

• It causes a different shift in the reading frame, leading to a different sequence of amino acids.

• It does not change the amino acid sequence at all.

• It always produces the same amino acids as insertion mutations.

• It only affects the first amino acid.

Fill in the Blanks

A deletion mutation

a base.

Fill in the Blanks

An insertion mutation

a base.

Fill in the Blanks

Mutations may be harmful and may be the cause of many genetic disorders and

.

Multiple Select

Which of the following are possible benefits of mutations as described in the lesson? (select 3)

• Production of proteins with new or altered activities

• Increased usefulness to organisms in changing environments

• Advantageous traits for plant and animal breeders

• All mutations are harmful

Multiple Choice

What is a mutation in genetic material most commonly caused by?

• Mistake in transcription

• Balanced diet

• Physical exercise

• Environmental temperature

Multiple Choice

Which of the following is NOT a type of gene mutation shown in the diagram?

• Point Mutations

• Frameshift Mutations

• Insertion

• Translocation

Multiple Choice

Sickle cell anemia is caused by what type of mutation?

• deletion

• Frameshift

• substitution mutation

• insertion

Multiple Choice

If a point mutation does not change the order of the amino acid sequence, this is called a:

• nonsense mutation

• silent mutation

• missense mutation

• frameshift mutation

Multiple Choice

What type of gene mutation has occurred here? 
T-G-A-C-C-A
T-G-A-C-C-A-A

• Base Substitution
• Base Deletion
• Base Insertion
• Frameshift 

Multiple Choice

What type of gene mutation has occurred here? Normal-
AGA-TTC-ATA-GCG
Mutant-
AGA-TTC-AAT-AGC-G

• deletion frameshift
• insertion frameshift
• substitution
• nonsense

Multiple Choice

A mutation that does NOT show up through protein function is called

• deletion mutation
• inversion mutation
• silent mutation
• transverse mutation

Multiple Choice

A substitution mutation that has no effect

on amino acids sequence

• Insertion Mutation

• Translocation

• Silent Mutation

• Deletion Mutation

Multiple Choice

A nucleotide base is inserted or deleted shifting the entire DNA sequence. Entire protein will be changed.

• Substitution Mutation

• Silent Mutation

• Frameshift Mutation

• Translocation

Multiple Choice

Are all mutations bad?

• Yes
• No

Multiple Choice

Why are insertion and deletion mutations so harmful?

• They change all of the codons from the mutation on down the line, which changes the amino acid sequence

• They insert things that an organism doesn't need.

• They often delete things that organisms need.

• Insertion and deletions are not any more harmful than substitution mutations.

Multiple Choice

What type of mutation involves substituting a DNA base with a different base?

• point mutation

• frameshift mutation

• silent mutation

• chromosomal mutation