Pharmacokinetics

ABSORPTION: Absorption refers to the amount of drug that enters the ____________

• bloodstream

• liver

• pancreas

• target tissue

ABSORPTION: If 30% of a drug loses it's efficacy, the Bioavailability will be ___________

• negative

• 70%

• 30%

• 15%

Alternative routes of administration like suppository, intravenous, intramuscular, inhalational aerosol, transdermal and sublingual avoid the first-pass effect because they allow drugs to be absorbed directly into the systemic circulation.

• True

• False

ABSORPTION: Intravenous drugs have __________ bioavailability.

• zero

• 50%

• full

• 100%

ABSORPTION: _________ is an example of an antibiotic that is normally used IV to treat serious infections because it is so poorly absorbed orally.

• vancomycin

• clindamycin

• azithromycin

• gentamycin

DISTRIBUTION: One class of drugs that we discussed that requires therapy management for appropriate measurements includes:

• topical agents

• aerosol inhalers

• seizure meds

• antidepressants

DISTRIBUTION: A drug bound to a protein is _____________

• active

• mobile

• free

• inactive

DISTRIBUTION: ___________is the main protein that binds medications in the blood.

• albumin

• thrombin

• insulin

• oxytocin

DISTRIBUTION: Medications with a large volume of distribution generally have a ___________ blood concentration.

• larger

• lower

• similar

• stable

DISTRIBUTION: Most medications require a loading dose TRUE or FALSE

• True

• FALSE