AP Bio Mitosis Review

During mitosis in animal cells, at which phase do centrioles begin to move apart?

• prophase
• prometaphase
• metaphase
• anaphase

Where do the microtubules of the spindle originate during mitosis in animal cells?

• centromere
• centrosome
• centriole
• chromatid

Which of the following are primarily responsible for cytokinesis in plant cells but not in animal cells?

• tubulin and dynein
• actin and myosin
• centrioles and centromeres
• Golgi derived vesicles

Movement of the chromosomes during anaphase would be most affected by a drug that prevents

• nuclear envelope breakdown
• elongation of microtubules
• shortening of microtubules
• formation of a cleavage furrow

Measurements of the amount of DNA per nucleus were taken on a large number of cells from a growing fungus. The measured DNA levels ranged from 3 to 6 picograms per nucleus. In which stage of the cell cycle would the nucleus contain 6 picograms of DNA?

• G_o
• G₁
• S
• G₂

At which phase of mitosis do the sister chromatids become daughter chromosomes?

• prophase
• metaphase
• anaphase
• telophase

Diatoms and some yeasts are unicellular eukaryotes that have mechanisms of nuclear division that may resemble intermediate steps in the evolution of mitosis. Which of the following is a characteristic feature of nuclear division in these organisms?

• They have circular chromosomes that are segregated by attachment to the plasma membrane.
• They have circular chromosomes that are segregated by attachment to spindle microtubules.
• Chromosomes are not condensed during nuclear division.
• The nuclear envelope remains intact during division.

Cells from advanced malignant tumors frequently have very abnormal chromosomes as well as an abnormal number of chromosomes. What might explain the association between malignant tumors and chromosomal abnormalities?

• Cancer cells replicate chromosomes multiple times per cell cycle
• Cancer cells are no longer anchorage dependent
• Cell cycle checkpoints are not in place to stop cells with chromosome abnormalities
• Cells with abnormal chromosomes have increased metabolism

Which is the first checkpoint in the cell cycle where a cell will be caused to exit the cycle if this point is not passed

• G_o
• G₁
• G₂
• M

The cell cycle is regulated at the molecular level by a set of proteins known as

• ATPases.
• separase proteins
• cohesions
• cyclins