Quizizz Review (Mutations only)

Sickle-shaped red blood cells result from a mutation in the gene that codes for hemoglobin. This mutation results in sickle-cell anemia. A partial sequence of bases from a normal hemoglobin gene and a sequence that results in sickle-cell anemia are shown below.

What type of mutation is depicted in this sequence?

• Substitution

• Insertion

• Deletion

• Frameshift

Tags

NGSS.HS-LS3-2

A segment of DNA produces methionine, threonine, histidine, aspartate, and glycine when translated. A substitution mutation occurs and causes the synthesis of the segment as shown. Which is the new peptide chain when the new DNA segment is translated?

• Methionine, leucine, histidine, aspartate, glycine

• Methionine, phenylalanine, histidine, aspartate, glycine

• Methionine, proline, histidine, aspartate, glycine

• Methionine, serine, histidine, aspartate, glycine

Tags

NGSS.HS-LS3-2

NGSS.HS-LS1-1

The chart below illustrates the amino acids that a specific triplet creates. Which of the following mutations would result in a different protein being synthesized?

• AUA is mutated into AUU

• AGA is mutated into AGG

• AUU is mutated into ACU

• ACC is mutated into ACA

Tags

NGSS.HS-LS3-2

NGSS.HS-LS1-1

The survival of a species depends on its ability to adapt to changes in the environment. A species must be capable of surviving and reproducing despite changes to food sources, climate, or threats from predators. Which statement correctly describes a way that mutations increase the likelihood that a species will survive in a changing environment?

• Mutations are a source of variation in the species

• Mutations are the cause of disease in the species

• Mutations are not harmful when they occur in somatic cells of the species

• Mutations are always passed on to subsequent generations of the species

Tags

NGSS.HS-LS3-2

NGSS.HS-LS4-2

NGSS.HS-LS4-4

A certain mutation in the gene for hemoglobin results in the red blood cells becoming sticky, rigid, and irregularly shaped. These irregularly shaped red blood cells block the flow of blood throughout the body. A single base mutation is responsible for these irregularly shaped blood cells. Which of these mutations most likely results in the mutated hemoglobin gene?

• Insertion

• Deletion

• Duplication

• Substitution

Tags

NGSS.HS-LS3-2

NGSS.HS-LS1-1

A mutation is least likely to affect a cell when the mutation —

• reverses the order of bases in a DNA strand

• allows the total number of bases in a DNA sequence to remain the same

• replaces a base with its complementary base

• produces a triplet that codes for the same amino acid as the original triplet

Tags

NGSS.HS-LS3-2

NGSS.HS-LS4-2

Early-onset Alzheimer’s disease affects people under the age of 65. Less than five percent of people who are diagnosed with Alzheimer’s disease have this type. Many cases of early-onset Alzheimer’s disease are inherited, a type known as familial Alzheimer’s disease (FAD). Which statement is best supported by this information?

• FAD is the result of a genetic change in one or more chromosomes.

• Natural selection will continue to reduce the incidence of FAD.

• FAD affects only the genes of middle-aged people.

• Deletion of one amino acid causes FAD.

Tags

NGSS.HS-LS3-2

NGSS.HS-LS3-1

In the 1960s the molecular biologist George Streisinger developed the strand-slippage hypothesis. Streisinger noticed that mutations occurred in areas of DNA that contained many repeated sequences. When a strand-slippage error occurs, an insertion mutation can result. How does the insertion mutation affect the DNA?

• Nitrogenous bases are added.

• Nitrogenous bases are exchanged.

• Nitrogenous bases are damaged.

• Nitrogenous bases are deleted.

Tags

NGSS.HS-LS3-2

The table shows a DNA sequence and three types of mutations that can change the DNA sequence.

Which mutation will cause translation to stop?

• Mutations 1 and 3 only

• Mutation 1 only

• Mutation 2 only

• Mutations 1, 2, and 3

Tags

NGSS.HS-LS3-2

NGSS.HS-LS1-1

Different types of mutations can occur in DNA. The diagram represents a type of mutation.

Which statement describes the mutation in the diagram?

• A silent mutation results in the insertion of a different amino acid.

• A substitution occurs with the adenine base.

• A deletion of a cytosine base occurs.

• A base is inserted into one strand of the DNA.

Tags

NGSS.HS-LS3-2