Principles of Drug Action

Which of the following is the process involving the movement of drug molecules from the site of entry into the body to the circulation

• Bioavailability

• Distribution

• Absorption

• Solubility

Which of the following is the process through which the body inactivates a drug after the drug has been used in order to eliminate the drug from the body?

• Synergism

• Meatabolism

• Pontentiation

• Bioavailability

What are three general properties of drugs?

• Modify existing function

• Exert multiple actions

• Single effect

• Reaction between physiochemical interaction and molecule in the body

Protein binding decreases the amount of free drug circulation

• True

• False

The _______ of absorption depends on the route of administration.

• rate

• slowliness

• mass

• none of the above

Two routes of drug administration are?

• injection and oral

• absorption and distribution

• tissue and excretion

• plasma and binding

Drugs do not confer any new functions on a _________?

• ears and nose

• tissue and organs

• bones and tissue

• none of the above

To produce its optimal effect a drug must reach appropriate concentrations at its site of action.

• true

• false

Lipid soluble drugs have a high affinity for?

• subcutaneous tissue

• bones

• dissolved tissue

• adipose tissue

Compounds that are strongly ionized and poorly soluble fat can enter the brain.

• True

• False