Herpesviruses

The following are the characteristic features of Herpesviridae family EXCEPT

• Replication in the host cell cytoplasm

• Establish latent infections

• Persists indefinitely and undergoes periodic reactivation

• Reactivated infection may be clinically different

The glycoprotein that is type-specific for differentiation of HSV1 and HSV2 is

• Glycoprotein G

• Glycoprotein C

• Glycoprotein B

• Glycoprotein D

The following are B herpes viruses EXCEPT

• CMV

• HHV6

• HHV7

• HHV8 or KSHV

Recurrences of genital herpes are

• More with HSV-2 than HSV-1

• Same in both HSV-1 and HSV-2

• More in HSV-1 than HSV-2

• Variable and insignificant with either type of HSV

Oral Acyclovir therapy in the treatment of chickenpox leads to the following EXCEPT

• Prevents the development of Zoster

• Shortens the duration of lesion formation

• Reduces the total number of new lesions by 25 %

• Diminishes constitutional symptoms in one-third of patients

For the diagnosis of generalized herpes infection was studied blood serum to detect specific antibodies of specific class. Antibodies of which class indicate the acute phase of viral infection?

• Ig M

• Ig A

• Ig E

• Ig D

• Ig. G

The main route of transmission of herpes simplex virus:

• Alimentary

• Contact

• Parenteral

• Air and dust

• Transplacental

As a rapid diagnosis of herpes infection apply:

• Enzyme Immunoassay

• The reaction of neutralization

• Immunofluorescence method

• Radioimmunoassay

• The reaction of hemagglutination

A patient has fever and the appearance of vesicles, which are located on the edge of the skin and mucous membranes. Through which research methods can confirm the presence in the patient of herpes simplex virus?

• Microscopic and allergic

• Virological and serological

• Virological and biological

• Serological and biological

• Microscopy and biological

Patient appealed to the dentist complained of vesicular rash around the mouth. Which method should be applied to confirm the diagnosis "herpes"?

• Microscopic examination of smears

• Heamagglutinin

• Seeding on blood agar

• Seeding to Kitt Tarotstsi medium

• Immunofluorescence reaction