PHAR 7613 - Exam III, Pt. 1

Select all of the following false statements regarding BP regulation.

• Changes in cardiac output will affect blood pressure

• Changes in peripheral vascular resistance will affect blood pressure

• Mean arterial pressure is equal to heart rate x peripheral resistance

• Alterations in baroreceptor activity will affect blood pressure

• Activation of Beta-3 receptors will affect SV and CO; therefore, it will affect blood pressure.

Increased sympathetic output is associated with which of the following? Select all of that apply.

• Increased PVR

• Increased HR

• Increased contractility of cardiac muscles

• Increased SV

• Increased CO

All of the following statements concerning the baroreceptor reflex are true except ____ (Select all of the incorrect statements)

• A decrease in baroreceptor activity leads to an increase in parasympathetic activity

• A decrease in baroreceptor activity leads to an increase in sympathetic activity

• Increased parasympathetic activity leads to increased cardiac output

• Baroreceptor activity increases when BP drops

• Increased sympathetic activity leads to increased cardiac output

Which of the following statements concerning the beta blockers is false?

• They can lower blood pressure

• They can increase heart rate

• They can decrease cardiac muscle contractility

• They can reduce PVR with long-term use

• Non-selective beta blockers may be harmful to asthmatic patients

Which of the following antihypertensive drugs is most likely to cause orthostatic hypotension?

• Doxazosin

• Methyldopa

• Metoprolol

• Clonidine

• Propranolol

Which of the following beta blockers has an additional Alpha-1 blockade property that can enhance its effect on lowering blood pressure?

• Propranolol

• Timolol

• Metoprolol

• Carvedilol

• Nadolol

Alpha-1 blockers can be used as antihypertensives because they can:

• Decrease HR

• Decrease SV

• Decrease PVR

• Decrease CO

• Act centrally (on the CNS)

Beta blockers can be used as antihypertensives because they can ____ (select all that apply)

• Decrease HR

• Decrease SV

• Decrease PVR

• Decrease CO

• Act centrally (on the CNS)

Which of the following antihypertensives may be used in patients with bronchial asthma? Select all that apply.

• Bisoprolol

• Carvedilol

• Atenolol

• Nadolol

• Timolol

Which of the following antihypertensive MOAs is shared by clonidine and alpha-methyldopa?

• Stimulation of alpha-1 receptors in blood vessels

• Inhibiting alpha-2 receptors in the CNS

• Blocking beta-1 receptors in the heart

• Stimulating alpha-2 receptors in the CNS

• Blocking beta-2 receptors in the bronchioles