Diabetes: Oral Meds

Which of the following classes is first line for T2DM?

• Biguanides

• TZDs

• DPP-4 Inhibitors

• SGLT-2 Inhibitors

TZDs (Pioglitazone + Rosiglitazone) carry the following risks, EXCEPT

• Weight Gain

• Bladder Cancer

• Anovulation

• Fluid Retention / Heart Failure

T/F: Glimepiride, Glipizide, and Glyburide are the Sulfonylureas available to patients with an allergy to sulfa

• True

• False

A patient on Nateglinide or Repaglinide (Metglinide class) should only skip a dose if ….

• Their BG is <150

• They are fasting

• They consumed two slices of pizza

Which one of the following DPP-4 Inhibitors does not require renal dose adjustment?

• Sitagliptin (Januvia)

• Saxagliptin (Onglyza)

• Linagliptin (Tradjenta)

• Alogliptin (Nesina)

This class of medications is required to be taken with the first bite of food.

• SGLT-2 (ex. Canagliflozin)

• AGIs (ex. Acarbose)

• SURs (ex. Glyburide)

• TZDs (ex. Pioglitazone)

SGLT-2 Inhibitors [Invokana, Farxiga, Jardiance, Steglarto] carry the following risks, EXCEPT

• BP elevation

• UTIs

• Lower Limb Amputation

• Dehydration

T/F: Bile Acid Sequestrants (Welchol) reduce A1c ~0.4% and should be separated from medications like glyburide, levothyroxine, digoxin, warfarin by about 4 hours.

• True

• False

What is the brand name for Sitagliptin?

• Farxiga

• Glucotrol

• Januvia

• Invokana

Which sulfonylurea is preferred in those with impaired renal function?

• Glyburide

• Glipizide

• Glimiperide